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P0CD72 (G6PI_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:CT_378
OrganismChlamydia trachomatis (strain D/UW-3/Cx) [Reference proteome] [HAMAP]
Taxonomic identifier272561 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length525 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 525525Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180620

Sites

Active site3471Proton donor By similarity
Active site3781 By similarity
Active site4931 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0CD72 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: 41F37FEDFC4C233E

FASTA52557,771
        10         20         30         40         50         60 
MMGKGFLDCE SLVALQEMAL HPIDLTASGC LSEERIQKNS LSAEGFTYSY ATERVDDRCL 

        70         80         90        100        110        120 
EALQGLTEER ELIKQMECMQ QGAIMNRIEG FQSESRPVLH TATRAWVRDQ DLHEEAAAIA 

       130        140        150        160        170        180 
RHSKEEALRL AEFLYIARAK FSTLVQMGIG GSELGPKAMY FAMQGSCPSD KRIFFVSNID 

       190        200        210        220        230        240 
PDNAAEVLRE IDLEQTLVVV VSKSGTTLEP AANEELFRQA YQNKGLSIAE HFVAVTSQGS 

       250        260        270        280        290        300 
PMDDKSRYLE VFHLWDSIGG RFSATSMVGG VVLGFAFGYE AFIEFLQGAA AIDAHALTPK 

       310        320        330        340        350        360 
MRENLPLLSA MLGVWNRNLL GYPTTAVIPY STGLKYFTAH LQQCGMESNG KSISREGKEI 

       370        380        390        400        410        420 
SFRTSPIIWG DVGTNCQHSF FQSLHQGTDI VPVEFIGFLH NQRGLDCVLS GSSSSQKLFA 

       430        440        450        460        470        480 
NLVAQSLALA QGRDNANSNK RFKGNRPSSI LVAQQLSPRI AGSLLAFYEH KFAFQGFCWG 

       490        500        510        520 
INSFDQEGVS LGKELATQII GIMSGNAPVE FSEARGMLRL FNVLT 

« Hide

References

[1]"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."
Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.
Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: D/UW-3/Cx.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001273 Genomic DNA. Translation: AAC67974.1.
PIRF71521.
RefSeqNP_219887.1. NC_000117.1.

3D structure databases

ProteinModelPortalP0CD72.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC67974; AAC67974; CT_378.
GeneID884740.
KEGGctr:CT_378.
PATRIC20380305. VBIChlTra43535_0407.

Phylogenomic databases

KOK01810.
OMAISIYESN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CHLTR
AccessionPrimary (citable) accession number: P0CD72
Secondary accession number(s): O84382, Q46402
Entry history
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 11, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways