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P0CD61 (GPT_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

EC=2.7.8.15
Alternative name(s):
GlcNAc-1-P transferase
Short name=G1PT
Short name=GPT
N-acetylglucosamine-1-phosphate transferase
Gene names
Name:alg7
ORF Names:DDB_G0290751
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides By similarity.

Catalytic activity

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the glycosyltransferase 4 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
PRO_0000391334

Regions

Transmembrane6 – 2621Helical; Potential
Transmembrane32 – 5221Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane120 – 14021Helical; Potential
Transmembrane147 – 16721Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane221 – 24121Helical; Potential
Transmembrane258 – 27821Helical; Potential
Transmembrane297 – 31721Helical; Potential
Transmembrane351 – 37121Helical; Potential
Transmembrane376 – 39621Helical; Potential
Motif95 – 10713Dolichol recognition
Motif259 – 27113Dolichol recognition
Compositional bias243 – 2508Poly-Ser

Sequences

Sequence LengthMass (Da)Tools
P0CD61 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: 98CBC6C4BCFB5602

FASTA40845,452
        10         20         30         40         50         60 
MIFDKSLLGF IGICCLPPIL LLIYLPNVSL QWIIVQSGFF SFGAGLLTYK LIPSVADLTS 

        70         80         90        100        110        120 
QANLTGMDLN KKGDPKFSGK KIPESLGICV AVVYLVCVIL FQTFQWFSFP ETIQLSEYNA 

       130        140        150        160        170        180 
ALTSICFMIL LGFGDDVLNL RWRYKLILPM FASLPLLVAY AGGTTVVVPD INFPVPLREW 

       190        200        210        220        230        240 
LGVVFDLGIF YRIYLLMLAI FCTNSINILA GINGLEVGQS VVIATSIIIH NLIELTIASS 

       250        260        270        280        290        300 
VPSSSSFSSS ALSSVSPHLF SLILMIPFLF TTISLLFYNW YPSRVFVGDT YTYFSGMCFA 

       310        320        330        340        350        360 
VVAILCHFSK TLLLFFIPQI LNFLYSVPQL FGIIPCPRHR VPKFNPETGK MEAIPTNLTI 

       370        380        390        400 
INLLLMITGP LTERQLCVYL LIFQGLCSCV GFGIRYHHLH HNPTLIFI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000168 Genomic DNA. No translation available.
AAFI02000169 Genomic DNA. No translation available.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

dictyBaseDDB_G0290751. alg7.

Phylogenomic databases

OMAHEEKLTW.
PhylomeDBP0CD61.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR000715. Glycosyl_transferase_4.
[Graphical view]
PfamPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP0CD61.

Entry information

Entry nameGPT_DICDI
AccessionPrimary (citable) accession number: P0CD61
Entry history
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: February 9, 2010
Last modified: April 16, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase