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P0CAW5 (RNPH_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease PH
Short name=RNase PH
EC=2.7.7.56
Alternative name(s):
tRNA nucleotidyltransferase
Gene names
Name:rph
Ordered Locus Names:CC_0152
OrganismCaulobacter crescentus (Caulobacter vibrioides)
Taxonomic identifier155892 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP MF_00564

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP MF_00564

Sequence similarities

Belongs to the RNase PH family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Ribonuclease PH HAMAP MF_00564
PRO_0000139880

Sequences

Sequence LengthMass (Da)Tools
P0CAW5 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 8DC29753AD7EFE58

FASTA23825,549
        10         20         30         40         50         60 
MRPSERAPDQ LRAVTLETGV NRYAEGSCLI GFGHTKVLVT ATVEENVPGW MRNKGAGWVT 

        70         80         90        100        110        120 
AEYGMLPRAT HTRGRREAAA GKQTGRTQEI QRLIGRSLRA VVDLKALGER QITLDCDVVQ 

       130        140        150        160        170        180 
ADGGTRTAAI TGAWVALRLA TKYLLDEGVL KTDPILGQVA AVSCGVFNGV PVLDLDYEED 

       190        200        210        220        230 
SNAEADSNFV LTGVGDIVEI QATGEKRGFT RAEFESLYGL AEKGINELFA LQRAAIGG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005673 Genomic DNA. Translation: AAK22139.1.
PIRG87267.
RefSeqNP_418971.1. NC_002696.2.

3D structure databases

ProteinModelPortalP0CAW5.
SMRP0CAW5. Positions 2-236.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID944212.
GenomeReviewsGene locus CC_0152 in contig AE005673_GR.
KEGGccr:CC_0152.
PATRIC21297220. VBICauCre124313_0149.
TIGRCC_0152.

Phylogenomic databases

OMAMLPRATG.
ProtClustDBPRK00173.

Family and domain databases

HAMAPMF_00564. RNase_PH.
[Tree]
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
KOK00989.
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF55666. 3_ExoRNase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPH_CAUCR
AccessionPrimary (citable) accession number: P0CAW5
Secondary accession number(s): P48196
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: June 16, 2009
Last modified: January 25, 2012
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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