P0C9H9 (1106L_ASFM2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein MGF 110-6L

Gene names

Ordered Locus Names:

Mal-011

Organism

African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV) [Complete proteome]

Taxonomic identifier

10500 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Asfarviridae › Asfivirus › African swine fever virus

Virus host

Ornithodoros (relapsing fever ticks) [TaxID: 6937]
Phacochoerus aethiopicus (Warthog) [TaxID: 85517]
Phacochoerus africanus (Warthog) [TaxID: 41426]
Potamochoerus larvatus (Bushpig) [TaxID: 273792]
Sus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length	118 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages By similarity.
Sequence similarities	Belongs to the asfivirus MGF 110 family.

Ontologies

Keywords
Developmental stage	Early protein
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 118	100	Protein MGF 110-6L		PRO_0000373201
Regions
	Motif	115 – 118	4	Prevents secretion from ER Potential

Sequences

	Sequence		Length	Mass (Da)
	P0C9H9 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 2F0E5828D5695932	FASTA	118	13,791
	10 20 30 40 50 60 MLVTFLGILG LLASQVSSQL VGQLRPTEDP PEEELEYWCA YMESCQFCWD CQDGNCINKI 70 80 90 100 110 DGSVIYKNEY VRPCSVSRSM DKCMYDLNKG IYHSMSCSDP KAWNPYKYFR KEWKKDEL

References

[1]	"African swine fever virus genomes." Kutish G.F., Rock D.L. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY261361 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR004848. V110_vir. [Graphical view]
Pfam	PF01639. v110. 1 hit. [Graphical view]
PROSITE	PS00014. ER_TARGET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

1106L_ASFM2

Accession

Primary (citable) accession number: P0C9H9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	January 11, 2011
This is version 5 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program