P0C9D4 (PAP1_ASFWA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative poly(A) polymerase catalytic subunit
EC=2.7.7.19

Gene names

Ordered Locus Names:

War-077

Organism

African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV) [Complete proteome]

Taxonomic identifier

561444 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Asfarviridae › Asfivirus › African swine fever virus

Virus host

Ornithodoros (relapsing fever ticks) [TaxID: 6937]
Phacochoerus aethiopicus (Warthog) [TaxID: 85517]
Phacochoerus africanus (Warthog) [TaxID: 41426]
Potamochoerus larvatus (Bushpig) [TaxID: 273792]
Sus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Polymerase that creates the 3'-poly(A) tail of mRNA's Potential.
Catalytic activity	ATP + RNA(n) = diphosphate + RNA(n+1).
Sequence similarities	Belongs to the poxviridae poly(A) polymerase catalytic subunit family. Highly divergent.

Ontologies

Keywords
Biological process	Transcription mRNA processing
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW polynucleotide adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 475	475	Putative poly(A) polymerase catalytic subunit		PRO_0000373150

Sequences

	Sequence		Length	Mass (Da)
	P0C9D4 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 175DF065754C59FA	FASTA	475	54,719
	10 20 30 40 50 60 MSSLLKPDFN VSKYRLIAQK REANAVEIEA ALEVVREFII KKKLILYGGI AIDYALHLKG 70 80 90 100 110 120 SSIYPEGERP DFDMFSPNHV EDAYELADIL YEKGFKQVGT VRAIHVQTMR VRTDFVWVAD 130 140 150 160 170 180 LSYMPPNIFD TIPTLTYKNL KIIHPDYQRA GLHLAFCFPF DNPPREDVFS RFKKDLQRYN 190 200 210 220 230 240 LIEKYYPIPV VPVKSTYESK TFSIPFKQVA IHGFAAYALL YQTLNELRIT CKVPEWKTEF 250 260 270 280 290 300 PQPSYSYHKN DKNITLTIDM PRAYPALVLA TYNPEGVIKE MGLHLTEICE PYMDYSPPIF 310 320 330 340 350 360 KTNDIHFFST MFKELAISII QDNLIVVSPQ YLLLYFLYGA FATPADKSLF LFYYNATLWI 370 380 390 400 410 420 LEKADSLLNI IQKQTSPEEF TRFANTSPFV LTTRVLSCSQ ERCTFSPAYR ISLANDVQQS 430 440 450 460 470 QLPLPKTHFL SNSLPDISTL PYNYYPGKGK EKPTNFSYEK NLLFNIGGKC TPSAM

References

[1]	"African swine fever virus genomes." Kutish G.F., Rock D.L. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY261366 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PAP1_ASFWA

Accession

Primary (citable) accession number: P0C9D4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	May 31, 2011
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program