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Protein

Rusticyanin

Gene

rus

Organism
Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Electron carrier from cytochrome c552 to the A-type oxidase.

Cofactori

Cu cationNote: Binds 1 copper ion per subunit.

Redox potential

E0 is +680 mV.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi117Copper1
Metal bindingi170Copper1
Metal bindingi175Copper1
Metal bindingi180Copper1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Copper, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16161.

Names & Taxonomyi

Protein namesi
Recommended name:
Rusticyanin
Gene namesi
Name:rus
Synonyms:rusTA
OrganismiAcidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)
Taxonomic identifieri920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32By similarityAdd BLAST32
ChainiPRO_000000287233 – 187RusticyaninAdd BLAST155

Expressioni

Inductioni

Expressed during growth on Fe2+, sulfur and thiosulfate.1 Publication

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

STRINGi380394.Lferr_2743.

Structurei

Secondary structure

1187
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi40 – 42Combined sources3
Helixi44 – 51Combined sources8
Beta strandi57 – 59Combined sources3
Beta strandi62 – 64Combined sources3
Beta strandi67 – 77Combined sources11
Beta strandi86 – 88Combined sources3
Beta strandi91 – 93Combined sources3
Beta strandi95 – 99Combined sources5
Beta strandi103 – 110Combined sources8
Beta strandi120 – 123Combined sources4
Beta strandi139 – 141Combined sources3
Beta strandi151 – 159Combined sources9
Beta strandi163 – 169Combined sources7
Turni173 – 175Combined sources3
Helixi176 – 178Combined sources3
Beta strandi181 – 187Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A3ZX-ray1.90A33-187[»]
1A8ZX-ray2.10A39-187[»]
1CURNMR-A38-187[»]
1E30X-ray1.50A/B38-187[»]
1GY1X-ray1.65A/B38-187[»]
1GY2X-ray1.82A/B38-187[»]
1RCYX-ray1.90A38-187[»]
2CAKX-ray1.27A38-187[»]
2CALX-ray1.10A38-187[»]
SMRiP0C918.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0C918.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini85 – 187Plastocyanin-likeAdd BLAST103

Sequence similaritiesi

Contains 1 plastocyanin-like domain.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR000923. BlueCu_1.
IPR028871. BlueCu_1_BS.
IPR033138. Cu_oxidase_CS.
IPR008972. Cupredoxin.
IPR001243. Rusticyanin.
[Graphical view]
PfamiPF00127. Copper-bind. 1 hit.
[Graphical view]
PRINTSiPR00158. RUSTICYANIN.
SUPFAMiSSF49503. SSF49503. 1 hit.
TIGRFAMsiTIGR03095. rusti_cyanin. 1 hit.
PROSITEiPS00196. COPPER_BLUE. 1 hit.
PS00079. MULTICOPPER_OXIDASE1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C918-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTQNTMKKN WYVTVGAAAA LAATVGMGTA MAGTLDSTWK EATLPQVKAM
60 70 80 90 100
LEKDTGKVSG DTVTYSGKTV HVVAAAVLPG FPFPSFEVHD KKNPTLEIPA
110 120 130 140 150
GATVDVTFIN TNKGFGHSFD ITKKGPPYAV MPVIDPIVAG TGFSPVPKDG
160 170 180
KFGYTDFTWH PTAGTYYYVC QIPGHAATGM FGKIIVK
Length:187
Mass (Da):19,857
Last modified:April 14, 2009 - v1
Checksum:iBA1DA44A5BE95981
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ006456 Genomic DNA. Translation: CAA07038.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ006456 Genomic DNA. Translation: CAA07038.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A3ZX-ray1.90A33-187[»]
1A8ZX-ray2.10A39-187[»]
1CURNMR-A38-187[»]
1E30X-ray1.50A/B38-187[»]
1GY1X-ray1.65A/B38-187[»]
1GY2X-ray1.82A/B38-187[»]
1RCYX-ray1.90A38-187[»]
2CAKX-ray1.27A38-187[»]
2CALX-ray1.10A38-187[»]
SMRiP0C918.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi380394.Lferr_2743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16161.

Miscellaneous databases

EvolutionaryTraceiP0C918.

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR000923. BlueCu_1.
IPR028871. BlueCu_1_BS.
IPR033138. Cu_oxidase_CS.
IPR008972. Cupredoxin.
IPR001243. Rusticyanin.
[Graphical view]
PfamiPF00127. Copper-bind. 1 hit.
[Graphical view]
PRINTSiPR00158. RUSTICYANIN.
SUPFAMiSSF49503. SSF49503. 1 hit.
TIGRFAMsiTIGR03095. rusti_cyanin. 1 hit.
PROSITEiPS00196. COPPER_BLUE. 1 hit.
PS00079. MULTICOPPER_OXIDASE1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRUS2_ACIFR
AccessioniPrimary (citable) accession number: P0C918
Secondary accession number(s): P24930
, P74919, Q56297, Q56298
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: November 2, 2016
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

The two different versions of rusticyanins are most probably due to strain variations.Curated

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.