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P0C8N0

- 14KL_BRUAB

UniProt

P0C8N0 - 14KL_BRUAB

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Protein
Lectin-like protein BA14k
Gene
BruAb2_0497
Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport By similarity.

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Keywords - Ligandi

Lectin

Enzyme and pathway databases

BioCyciBABO262698:GJC2-2709-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lectin-like protein BA14k
Gene namesi
Ordered Locus Names:BruAb2_0497
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei80 – 10021Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626 Reviewed prediction
Add
BLAST
Chaini27 – 147121Lectin-like protein BA14k
PRO_0000361297Add
BLAST

Proteomic databases

PRIDEiP0C8N0.

Interactioni

Protein-protein interaction databases

STRINGi262698.BruAb2_0497.

Family & Domainsi

Sequence similaritiesi

Belongs to the BA14k family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG08130.
HOGENOMiHOG000274446.
OMAiHVAWCAN.
OrthoDBiEOG6358FW.

Family and domain databases

InterProiIPR012413. BA14K.
[Graphical view]
PfamiPF07886. BA14K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C8N0-1 [UniParc]FASTAAdd to Basket

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MNSFRKTCAG ALALIFGATS IVPTVAAPMN MDRPAINQNV IQARAHYRPQ    50
NYNRGHRPGY WHGHRGYRHY RHGYRRHNDG WWYPLAAFGA GAIIGGAISQ 100
PRPVYRAPAG SPHVQWCYSR YKSYRASDNT FQPYNGPRKQ CRSPYSR 147
Length:147
Mass (Da):16,823
Last modified:January 20, 2009 - v1
Checksum:i7CEE6F1FB2BB38DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75916.1.
PIRiAG3578.
RefSeqiYP_223277.1. NC_006933.1.

Genome annotation databases

EnsemblBacteriaiAAX75916; AAX75916; BruAb2_0497.
GeneIDi3342101.
KEGGibmb:BruAb2_0497.
PATRICi17827256. VBIBruAbo15061_2806.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75916.1 .
PIRi AG3578.
RefSeqi YP_223277.1. NC_006933.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb2_0497.

Proteomic databases

PRIDEi P0C8N0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX75916 ; AAX75916 ; BruAb2_0497 .
GeneIDi 3342101.
KEGGi bmb:BruAb2_0497.
PATRICi 17827256. VBIBruAbo15061_2806.

Phylogenomic databases

eggNOGi NOG08130.
HOGENOMi HOG000274446.
OMAi HVAWCAN.
OrthoDBi EOG6358FW.

Enzyme and pathway databases

BioCyci BABO262698:GJC2-2709-MONOMER.

Family and domain databases

InterProi IPR012413. BA14K.
[Graphical view ]
Pfami PF07886. BA14K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry namei14KL_BRUAB
AccessioniPrimary (citable) accession number: P0C8N0
Secondary accession number(s): Q44701, Q578L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 20, 2009
Last modified: May 14, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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