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P0C8N0

- 14KL_BRUAB

UniProt

P0C8N0 - 14KL_BRUAB

Protein

Lectin-like protein BA14k

Gene

BruAb2_0497

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (20 Jan 2009)
      Previous versions | rss
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    Functioni

    Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport By similarity.By similarity

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Virulence

    Keywords - Ligandi

    Lectin

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-2709-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lectin-like protein BA14k
    Gene namesi
    Ordered Locus Names:BruAb2_0497
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome II

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 147121Lectin-like protein BA14kPRO_0000361297Add
    BLAST

    Proteomic databases

    PRIDEiP0C8N0.

    Interactioni

    Protein-protein interaction databases

    STRINGi262698.BruAb2_0497.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei80 – 10021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the BA14k family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG08130.
    HOGENOMiHOG000274446.
    OMAiHVAWCAN.
    OrthoDBiEOG6358FW.

    Family and domain databases

    InterProiIPR012413. BA14K.
    [Graphical view]
    PfamiPF07886. BA14K. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P0C8N0-1 [UniParc]FASTAAdd to Basket

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    MNSFRKTCAG ALALIFGATS IVPTVAAPMN MDRPAINQNV IQARAHYRPQ    50
    NYNRGHRPGY WHGHRGYRHY RHGYRRHNDG WWYPLAAFGA GAIIGGAISQ 100
    PRPVYRAPAG SPHVQWCYSR YKSYRASDNT FQPYNGPRKQ CRSPYSR 147
    Length:147
    Mass (Da):16,823
    Last modified:January 20, 2009 - v1
    Checksum:i7CEE6F1FB2BB38DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017224 Genomic DNA. Translation: AAX75916.1.
    PIRiAG3578.
    RefSeqiYP_223277.1. NC_006933.1.

    Genome annotation databases

    EnsemblBacteriaiAAX75916; AAX75916; BruAb2_0497.
    GeneIDi3342101.
    KEGGibmb:BruAb2_0497.
    PATRICi17827256. VBIBruAbo15061_2806.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017224 Genomic DNA. Translation: AAX75916.1 .
    PIRi AG3578.
    RefSeqi YP_223277.1. NC_006933.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb2_0497.

    Proteomic databases

    PRIDEi P0C8N0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX75916 ; AAX75916 ; BruAb2_0497 .
    GeneIDi 3342101.
    KEGGi bmb:BruAb2_0497.
    PATRICi 17827256. VBIBruAbo15061_2806.

    Phylogenomic databases

    eggNOGi NOG08130.
    HOGENOMi HOG000274446.
    OMAi HVAWCAN.
    OrthoDBi EOG6358FW.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-2709-MONOMER.

    Family and domain databases

    InterProi IPR012413. BA14K.
    [Graphical view ]
    Pfami PF07886. BA14K. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry namei14KL_BRUAB
    AccessioniPrimary (citable) accession number: P0C8N0
    Secondary accession number(s): Q44701, Q578L8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: January 20, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3