P0C8N0 (14KL_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lectin-like protein BA14k

Gene names

Ordered Locus Names:

BruAb2_0497

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport By similarity.
Subcellular location	Cell membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the BA14k family.

Ontologies

Keywords
Biological process	Virulence
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane helix
Ligand	Lectin
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pathogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential
	Chain	27 – 147	121	Lectin-like protein BA14k		PRO_0000361297
Regions
	Transmembrane	80 – 100	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P0C8N0 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: 7CEE6F1FB2BB38DB	FASTA	147	16,823
	10 20 30 40 50 60 MNSFRKTCAG ALALIFGATS IVPTVAAPMN MDRPAINQNV IQARAHYRPQ NYNRGHRPGY 70 80 90 100 110 120 WHGHRGYRHY RHGYRRHNDG WWYPLAAFGA GAIIGGAISQ PRPVYRAPAG SPHVQWCYSR 130 140 YKSYRASDNT FQPYNGPRKQ CRSPYSR

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017224 Genomic DNA. Translation: AAX75916.1.
PIR	AG3578.
RefSeq	YP_223277.1. NC_006933.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb2_0497.
Proteomic databases
PRIDE	P0C8N0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX75916; AAX75916; BruAb2_0497.
GeneID	3342101.
KEGG	bmb:BruAb2_0497.
PATRIC	17827256. VBIBruAbo15061_2806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG08130.
HOGENOM	HOG000274446.
OMA	YRPGYRP.
ProtClustDB	CLSK898873.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-2709-MONOMER.
Family and domain databases
InterPro	IPR012413. BA14K. [Graphical view]
Pfam	PF07886. BA14K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

14KL_BRUAB

Accession

Primary (citable) accession number: P0C8N0
Secondary accession number(s): Q44701, Q578L8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 20, 2009
Last sequence update:	January 20, 2009
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program