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P0C8E9 (EVA4_RHISA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Shows chemokine neutralizing activity. Binds to chemokines CCL5 and CCL11. Ref.1

Subunit structure

Monomer. Ref.1

Subcellular location

Secreted Potential.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   PTMGlycoprotein
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 127104Evasin-4
PRO_0000354059

Amino acid modifications

Glycosylation541N-linked (GlcNAc...) Potential
Glycosylation641N-linked (GlcNAc...) Potential
Glycosylation701N-linked (GlcNAc...) Potential
Glycosylation771N-linked (GlcNAc...) Potential
Glycosylation831N-linked (GlcNAc...) Potential
Glycosylation1061N-linked (GlcNAc...) Potential
Glycosylation1141N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P0C8E9 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: EF315B8BFE23E602

FASTA12714,126
        10         20         30         40         50         60 
MAFKYWFVFA AVLYARQWLS TKCEVPQMTS SSAPDLEEED DYTAYAPLTC YFTNSTLGLL 

        70         80         90        100        110        120 
APPNCSVLCN STTTWFNETS PNNASCLLTV DFLTQDAILQ ENQPYNCSVG HCDNGTCAGP 


PRHAQCW 

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References

[1]"Ticks produce highly selective chemokine binding proteins with antiinflammatory activity."
Deruaz M., Frauenschuh A., Alessandri A.L., Dias J.M., Coelho F.M., Russo R.C., Ferreira B.R., Graham G.J., Shaw J.P., Wells T.N.C., Teixeira M.M., Power C.A., Proudfoot A.E.I.
J. Exp. Med. 205:2019-2031(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBUNIT, FUNCTION.
Tissue: Salivary gland.

Web resources

Protein Spotlight

Hidden powers - Issue 99 of November 2008

Cross-references

3D structure databases

ProteinModelPortalP0C8E9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR007110. Ig-like_dom.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEVA4_RHISA
AccessionPrimary (citable) accession number: P0C8E9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: February 19, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries