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P0C8E8 (EVA3_RHISA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length86 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Shows chemokine neutralizing activity. Binds to chemokines CXCL1 and CXCL8. Ref.1

Subunit structure

Monomer. Ref.1

Subcellular location

Secreted Probable.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Ref.1
Chain21 – 8666Evasin-3
PRO_0000354058

Amino acid modifications

Glycosylation451N-linked (GlcNAc...) Potential
Glycosylation761N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P0C8E8 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 7FD0823DD19450D4

FASTA869,145
        10         20         30         40         50         60 
MRALLARLLL CVLVVSDSKG LVSTIESRTS GDGADNFDVV SCNKNCTSGQ NECPEGCFCG 

        70         80 
LLGQNKKGHC YKIIGNLSGE PPVVRR 

« Hide

References

[1]"Ticks produce highly selective chemokine binding proteins with antiinflammatory activity."
Deruaz M., Frauenschuh A., Alessandri A.L., Dias J.M., Coelho F.M., Russo R.C., Ferreira B.R., Graham G.J., Shaw J.P., Wells T.N.C., Teixeira M.M., Power C.A., Proudfoot A.E.I.
J. Exp. Med. 205:2019-2031(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF N-TERMINUS, SUBUNIT, FUNCTION.
Tissue: Salivary gland.

Web resources

Protein Spotlight

Hidden powers - Issue 99 of November 2008

Cross-references

3D structure databases

ProteinModelPortalP0C8E8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameEVA3_RHISA
AccessionPrimary (citable) accession number: P0C8E8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: February 19, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries