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Protein

JmjC domain-containing protein 7

Gene

Jmjd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
JmjC domain-containing protein 7
Alternative name(s):
Jumonji domain-containing protein 7
Gene namesi
Name:Jmjd7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3845785. Jmjd7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003493751 – 316JmjC domain-containing protein 7Add BLAST316

Proteomic databases

EPDiP0C872.
MaxQBiP0C872.
PRIDEiP0C872.

PTM databases

PhosphoSitePlusiP0C872.

Expressioni

Gene expression databases

BgeeiENSMUSG00000098789.
ExpressionAtlasiP0C872. baseline and differential.
GenevisibleiP0C872. MM.

Structurei

Secondary structure

1316
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi1 – 23Combined sources23
Beta strandi31 – 34Combined sources4
Helixi38 – 44Combined sources7
Turni45 – 49Combined sources5
Beta strandi52 – 56Combined sources5
Helixi63 – 66Combined sources4
Helixi69 – 76Combined sources8
Beta strandi79 – 89Combined sources11
Beta strandi92 – 95Combined sources4
Beta strandi98 – 101Combined sources4
Beta strandi103 – 108Combined sources6
Helixi109 – 117Combined sources9
Beta strandi118 – 120Combined sources3
Beta strandi123 – 128Combined sources6
Turni131 – 133Combined sources3
Helixi134 – 138Combined sources5
Helixi140 – 145Combined sources6
Helixi151 – 157Combined sources7
Beta strandi162 – 169Combined sources8
Beta strandi175 – 178Combined sources4
Beta strandi181 – 191Combined sources11
Beta strandi193 – 198Combined sources6
Helixi200 – 205Combined sources6
Beta strandi209 – 218Combined sources10
Beta strandi224 – 228Combined sources5
Beta strandi235 – 237Combined sources3
Beta strandi242 – 244Combined sources3
Turni247 – 249Combined sources3
Helixi251 – 255Combined sources5
Beta strandi259 – 263Combined sources5
Beta strandi267 – 271Combined sources5
Beta strandi276 – 281Combined sources6
Beta strandi285 – 293Combined sources9
Helixi298 – 312Combined sources15

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4QSZX-ray2.86A/B2-312[»]
4QU2X-ray2.70A/B1-316[»]
ProteinModelPortaliP0C872.
SMRiP0C872.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 307JmjCPROSITE-ProRule annotationAdd BLAST180

Sequence similaritiesi

Contains 1 JmjC domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000062914.
HOGENOMiHOG000264513.
HOVERGENiHBG054447.
InParanoidiP0C872.
KOiK19219.
OMAiCIIRNAF.
OrthoDBiEOG091G0G26.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C872-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAALEAVR RALQEFPAAA RDLNVPRVVP YLDEPPSPLC FYRDWVCPNR
60 70 80 90 100
PCIIRNALQH WPALQKWSLS YLRATVGSTE VSVAVTPDGY ADAVRGDRFV
110 120 130 140 150
MPAERRLPIS HVLDVLEGRA QHPGVLYVQK QCSNLPTELP QLLSDIESHV
160 170 180 190 200
PWASESLGKM PDAVNFWLGD ASAVTSLHKD HYENLYCVVS GEKHFLLHPP
210 220 230 240 250
SDRPFIPYNL YTPATYQLTE EGTFRVVDEE AMEKVPWIPL DPLAPDLTQY
260 270 280 290 300
PSYSQAQALH CTVRAGEMLY LPALWFHHVQ QSHGCIAVNF WYDMEYDLKY
310
SYFQLMDTLT RATGLD
Length:316
Mass (Da):35,917
Last modified:September 2, 2008 - v1
Checksum:i710E3887F066353E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016255 mRNA. Translation: AAH16255.1.
CCDSiCCDS50676.1.
RefSeqiNP_001108109.1. NM_001114637.1.
UniGeneiMm.482417.

Genome annotation databases

EnsembliENSMUST00000044675; ENSMUSP00000041220; ENSMUSG00000098789.
GeneIDi433466.
KEGGimmu:433466.
UCSCiuc008luy.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016255 mRNA. Translation: AAH16255.1.
CCDSiCCDS50676.1.
RefSeqiNP_001108109.1. NM_001114637.1.
UniGeneiMm.482417.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4QSZX-ray2.86A/B2-312[»]
4QU2X-ray2.70A/B1-316[»]
ProteinModelPortaliP0C872.
SMRiP0C872.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSitePlusiP0C872.

Proteomic databases

EPDiP0C872.
MaxQBiP0C872.
PRIDEiP0C872.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044675; ENSMUSP00000041220; ENSMUSG00000098789.
GeneIDi433466.
KEGGimmu:433466.
UCSCiuc008luy.2. mouse.

Organism-specific databases

CTDi100137047.
MGIiMGI:3845785. Jmjd7.

Phylogenomic databases

GeneTreeiENSGT00530000062914.
HOGENOMiHOG000264513.
HOVERGENiHBG054447.
InParanoidiP0C872.
KOiK19219.
OMAiCIIRNAF.
OrthoDBiEOG091G0G26.

Miscellaneous databases

PROiP0C872.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000098789.
ExpressionAtlasiP0C872. baseline and differential.
GenevisibleiP0C872. MM.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiJMJD7_MOUSE
AccessioniPrimary (citable) accession number: P0C872
Secondary accession number(s): A2AP62
, Q4QQM1, Q80VV8, Q91W88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Caution

This sequence was first thought to be an alternatively spliced isoform of Pla2g4b. It is derived from Jmjd7 which is located upstream of Pla2g4b. Most tissues also express read-through transcripts from Jmjd7 into the downstream Pla2g4b gene, some of which may encode fusion proteins combining the N-terminus of this protein with PLA2G4B protein.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.