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P0C856 (UREG1_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Urease accessory protein UreG 1
Gene names
Name:ureG1
Ordered Locus Names:BruAb1_0299
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG By similarity. HAMAP MF_01389

Subunit structure

Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.

Subcellular location

Cytoplasm By similarity HAMAP MF_01389.

Sequence similarities

Belongs to the UreG family.

Ontologies

Keywords
   Biological processNickel insertion
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: InterPro

GTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

nickel cation binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208Urease accessory protein UreG 1 HAMAP MF_01389
PRO_0000347354

Regions

Nucleotide binding14 – 218GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C856 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 39FF82812CA4FDE2

FASTA20822,705
        10         20         30         40         50         60 
MTQKNGPLRV GIGGPVGSGK TTLTEKLCKA MRDKYSVAVI TNDIYTQEDA LILARRQALS 

        70         80         90        100        110        120 
EDRIIGVETG GCPHTAIRED ASINLQAVVE MTRRFPDLDV VFIESGGDNL AATFSPDLAD 

       130        140        150        160        170        180 
LTLYVISVCQ GEEIPRKGGP GITRSDFLVI NKSDLAPYVH VDLEVMEADA MRMRAKRPFG 

       190        200 
FTDLHRGKGV QEIIDFIVEN GGLEPRSN 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX73702.1.
PIRAC3458.
RefSeqYP_221063.1. NC_006932.1.

3D structure databases

ProteinModelPortalP0C856.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3340616.
GenomeReviewsGene locus BruAb1_0299 in contig AE017223_GR.
KEGGbmb:BruAb1_0299.
PATRIC17822178. VBIBruAbo15061_0327.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG364734.
OMAPFIFTNL.
PhylomeDBP0C856.
ProtClustDBCLSK864148.

Family and domain databases

HAMAPMF_01389. UreG.
[Tree]
InterProIPR003495. Cbl_biosynth_CobW-like.
IPR012202. NiFe-hyd/urease_mat_GTPase.
IPR004400. Urease_accessory_UreG.
[Graphical view]
KOK03189.
PfamPF02492. cobW. 1 hit.
[Graphical view]
PIRSFPIRSF005624. Ni-bind_GTPase. 1 hit.
TIGRFAMsTIGR00101. UreG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUREG1_BRUAB
AccessionPrimary (citable) accession number: P0C856
Secondary accession number(s): Q57F82, Q93T78
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names

SIMILARITY comments

Index of protein domains and families