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P0C7P4 (UCRIL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative cytochrome b-c1 complex subunit Rieske-like protein 1
Alternative name(s):
Ubiquinol-cytochrome c reductase Rieske iron-sulfur subunit pseudogene 1
Gene names
Name:UQCRFS1P1
Synonyms:UQCRFSL1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Cofactor

Binds 1 2Fe-2S cluster.

Sequence similarities

Contains 1 Rieske domain.

Caution

Could be the product of a pseudogene.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Putative cytochrome b-c1 complex subunit Rieske-like protein 1
PRO_0000342402

Regions

Domain196 – 28186Rieske

Sites

Metal binding2261Iron-sulfur (2Fe-2S) By similarity
Metal binding2281Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
Metal binding2451Iron-sulfur (2Fe-2S) By similarity
Metal binding2481Iron-sulfur (2Fe-2S); via pros nitrogen By similarity

Amino acid modifications

Disulfide bond231 ↔ 247 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C7P4 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 00B1D0656BE89054

FASTA28330,815
        10         20         30         40         50         60 
MQQIYTVKEI RSVAARSGPF APVLSATSRG VAGALRPLVQ ATVPATPEQP VLDLKRPFLS 

        70         80         90        100        110        120 
RESLSGQAVR RPLVASVGLN VPASVCYSHT DIKVPDFSEY RRLEVLDSTK SSRESTEARK 

       130        140        150        160        170        180 
GFSYLVTGVT TVGVAYAAKN AVTQFVSSMS ASADVLALAK IEIKLSDIPE GKNMAFKWRG 

       190        200        210        220        230        240 
KPLFVRHRTQ KEIKQEAAVE LSQLRDPQHD LDRVKKPEWV ILIGVCTHLG CVPIANAGDF 

       250        260        270        280 
GGYYCPCHGS HYDASGRIRL GPATLNLEVP TYEFTSDDMV IVG 

« Hide

References

[1]"The DNA sequence of human chromosome 22."
Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M. expand/collapse author list , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Full-length cDNA libraries and normalization."
Li W.B., Gruber C., Jessee J., Polayes D.
Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 94-283.
Tissue: Neuroblastoma.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z82206 Genomic DNA. No translation available.
CR592425 mRNA. No translation available.

3D structure databases

ProteinModelPortalP0C7P4.
SMRP0C7P4. Positions 12-66, 88-283.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM193806571.

2D gel databases

UCD-2DPAGEP0C7P4.

Proteomic databases

MaxQBP0C7P4.
PaxDbP0C7P4.
PRIDEP0C7P4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC22P040273.
HGNCHGNC:12588. UQCRFS1P1.
HPAHPA041863.
neXtProtNX_P0C7P4.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0723.
HOGENOMHOG000255193.
HOVERGENHBG001040.
InParanoidP0C7P4.
PhylomeDBP0C7P4.

Gene expression databases

GenevestigatorP0C7P4.

Family and domain databases

Gene3D1.20.5.270. 1 hit.
2.102.10.10. 1 hit.
InterProIPR011070. Globular_prot_asu/bsu.
IPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR015248. Ubiqinol_cyt_c_Rdtase_N.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
IPR004192. Ubiquinol_cyt_Rdtase_TM.
[Graphical view]
PANTHERPTHR10134. PTHR10134. 1 hit.
PfamPF00355. Rieske. 1 hit.
PF09165. Ubiq-Cytc-red_N. 1 hit.
PF02921. UCR_TM. 1 hit.
[Graphical view]
PRINTSPR00162. RIESKE.
SUPFAMSSF50022. SSF50022. 1 hit.
SSF56568. SSF56568. 1 hit.
TIGRFAMsTIGR01416. Rieske_proteo. 1 hit.
PROSITEPS51296. RIESKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP0C7P4.

Entry information

Entry nameUCRIL_HUMAN
AccessionPrimary (citable) accession number: P0C7P4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 22

Human chromosome 22: entries, gene names and cross-references to MIM