P0C7N8 (OR9G9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Olfactory receptor 9G9

Gene names

Name:

OR9G9

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Odorant receptor Potential.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family.

Ontologies

Keywords
Biological process	Olfaction Sensory transduction
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	detection of chemical stimulus involved in sensory perception of smell Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW olfactory receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Olfactory receptor 9G9		PRO_0000341323
Regions
	Topological domain	1 – 27	27	Extracellular Potential
	Transmembrane	28 – 48	21	Helical; Name=1; Potential
	Topological domain	49 – 64	16	Cytoplasmic Potential
	Transmembrane	65 – 85	21	Helical; Name=2; Potential
	Topological domain	86 – 96	11	Extracellular Potential
	Transmembrane	97 – 117	21	Helical; Name=3; Potential
	Topological domain	118 – 138	21	Cytoplasmic Potential
	Transmembrane	139 – 159	21	Helical; Name=4; Potential
	Topological domain	160 – 200	41	Extracellular Potential
	Transmembrane	201 – 221	21	Helical; Name=5; Potential
	Topological domain	222 – 239	18	Cytoplasmic Potential
	Transmembrane	240 – 260	21	Helical; Name=6; Potential
	Topological domain	261 – 271	11	Extracellular Potential
	Transmembrane	272 – 291	20	Helical; Name=7; Potential
	Topological domain	292 – 305	14	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	5	1	N-linked (GlcNAc...) Potential
	Disulfide bond	96 ↔ 178		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P0C7N8 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 117FAFF585676631	FASTA	305	34,020
	10 20 30 40 50 60 MQRSNHTVTE FILLGFTTDP GMQLGLFVVF LGVYSLTVVG NSTLIVLICN DSHLHTPMYF 70 80 90 100 110 120 VVGNLSFLDL WYSSVYTPKI LVICISEDKS ISFAGCLCQF FFSAGLAYSE CCLLAAMAYD 130 140 150 160 170 180 RYVAISKPLL YAQAMSIKLC ALLVAVSYCG GFINSSIITK KTFSFNFCCE NIIDDFFCDL 190 200 210 220 230 240 LPLVKLACGE KGCYKFLMYF LLASNVICPA VLILASYLFI ITSVLRISSS QGRLKAFSTC 250 260 270 280 290 300 SSHLTSVTLY YGSILYIYAL PRSSYSFDMD KIVSTFYTEV LPMLNPMIYS LRNKDVKEAL KKLLP

References

[1]

Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Web resources

Human Olfactory Receptor Data Exploratorium (HORDE)

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH471076 Genomic DNA. Translation: EAW73723.1.
IPI	IPI00554566.
RefSeq	NP_001013376.1. NM_001013358.1.
UniGene	Hs.553752.
3D structure databases
ProteinModelPortal	P0C7N8.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000309012.
Protein family/group databases
GPCRDB	Search...
PTM databases
PhosphoSite	P0C7N8.
Proteomic databases
PRIDE	P0C7N8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	504191.
KEGG	hsa:504191.
UCSC	uc010rjn.2. human.
Organism-specific databases
CTD	504191.
GeneCards	GC11U900824.
HGNC	HGNC:31940. OR9G9.
neXtProt	NX_P0C7N8.
PharmGKB	PA142671224.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG017625.
InParanoid	P0C7N8.
KO	K04257.
Gene expression databases
Genevestigator	P0C7N8.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	112086.

Entry information

Entry name

OR9G9_HUMAN

Accession

Primary (citable) accession number: P0C7N8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.