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Protein

IQ domain-containing protein F3

Gene

IQCF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
IQ domain-containing protein F3
Gene namesi
Name:IQCF3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:31816. IQCF3.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134884625.

Polymorphism and mutation databases

BioMutaiIQCF3.
DMDMi190359730.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 154154IQ domain-containing protein F3PRO_0000339381Add
BLAST

Proteomic databases

PaxDbiP0C7M6.
PRIDEiP0C7M6.

PTM databases

iPTMnetiP0C7M6.
PhosphoSiteiP0C7M6.

Expressioni

Gene expression databases

BgeeiP0C7M6.
CleanExiHS_IQCF3.
ExpressionAtlasiP0C7M6. baseline and differential.
GenevisibleiP0C7M6. HS.

Interactioni

Protein-protein interaction databases

BioGridi134902. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP0C7M6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini89 – 11830IQPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 IQ domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410JDAG. Eukaryota.
ENOG41118ZM. LUCA.
GeneTreeiENSGT00390000004641.
HOGENOMiHOG000060238.
HOVERGENiHBG071368.
InParanoidiP0C7M6.
OMAiWQCHRRY.
OrthoDBiEOG7BGHNX.
PhylomeDBiP0C7M6.
TreeFamiTF337908.

Family and domain databases

InterProiIPR000048. IQ_motif_EF-hand-BS.
[Graphical view]
PfamiPF00612. IQ. 2 hits.
[Graphical view]
SMARTiSM00015. IQ. 2 hits.
[Graphical view]
PROSITEiPS50096. IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C7M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSKCCKGGP DEDAVERQRR QKLLLAQLHH RKRVKAAGQI QAWWRGVLVR
60 70 80 90 100
RTLLVAALRA WMIQCWWRTL VQRRIRQRRQ ALLRVYVIQE QATVKLQSCI
110 120 130 140 150
RMWQCRQCYR QMCNALCLFQ VPESSLAFQT DGFLQVQYAI PSKQPEFHIE

ILSI
Length:154
Mass (Da):18,251
Last modified:June 10, 2008 - v1
Checksum:i92DD0D3985D804B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057432 mRNA. No translation available.
AC097636 Genomic DNA. No translation available.
CH471055 Genomic DNA. Translation: EAW65154.1.
BC146874 mRNA. Translation: AAI46875.1.
BC146889 mRNA. Translation: AAI46890.1.
BC171811 mRNA. Translation: AAI71811.1.
BC171818 mRNA. Translation: AAI71818.1.
CCDSiCCDS46837.1.
RefSeqiNP_001078948.1. NM_001085479.2.
NP_001193952.1. NM_001207023.1.
UniGeneiHs.729443.

Genome annotation databases

EnsembliENST00000437810; ENSP00000409373; ENSG00000229972.
ENST00000440739; ENSP00000402012; ENSG00000229972.
ENST00000446775; ENSP00000401767; ENSG00000229972.
ENST00000456080; ENSP00000415609; ENSG00000229972.
GeneIDi401067.
KEGGihsa:401067.
UCSCiuc021wyy.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057432 mRNA. No translation available.
AC097636 Genomic DNA. No translation available.
CH471055 Genomic DNA. Translation: EAW65154.1.
BC146874 mRNA. Translation: AAI46875.1.
BC146889 mRNA. Translation: AAI46890.1.
BC171811 mRNA. Translation: AAI71811.1.
BC171818 mRNA. Translation: AAI71818.1.
CCDSiCCDS46837.1.
RefSeqiNP_001078948.1. NM_001085479.2.
NP_001193952.1. NM_001207023.1.
UniGeneiHs.729443.

3D structure databases

ProteinModelPortaliP0C7M6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi134902. 1 interaction.

PTM databases

iPTMnetiP0C7M6.
PhosphoSiteiP0C7M6.

Polymorphism and mutation databases

BioMutaiIQCF3.
DMDMi190359730.

Proteomic databases

PaxDbiP0C7M6.
PRIDEiP0C7M6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000437810; ENSP00000409373; ENSG00000229972.
ENST00000440739; ENSP00000402012; ENSG00000229972.
ENST00000446775; ENSP00000401767; ENSG00000229972.
ENST00000456080; ENSP00000415609; ENSG00000229972.
GeneIDi401067.
KEGGihsa:401067.
UCSCiuc021wyy.2. human.

Organism-specific databases

CTDi401067.
GeneCardsiIQCF3.
HGNCiHGNC:31816. IQCF3.
neXtProtiNX_P0C7M6.
PharmGKBiPA134884625.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JDAG. Eukaryota.
ENOG41118ZM. LUCA.
GeneTreeiENSGT00390000004641.
HOGENOMiHOG000060238.
HOVERGENiHBG071368.
InParanoidiP0C7M6.
OMAiWQCHRRY.
OrthoDBiEOG7BGHNX.
PhylomeDBiP0C7M6.
TreeFamiTF337908.

Miscellaneous databases

GenomeRNAii401067.
PROiP0C7M6.

Gene expression databases

BgeeiP0C7M6.
CleanExiHS_IQCF3.
ExpressionAtlasiP0C7M6. baseline and differential.
GenevisibleiP0C7M6. HS.

Family and domain databases

InterProiIPR000048. IQ_motif_EF-hand-BS.
[Graphical view]
PfamiPF00612. IQ. 2 hits.
[Graphical view]
SMARTiSM00015. IQ. 2 hits.
[Graphical view]
PROSITEiPS50096. IQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  2. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiIQCF3_HUMAN
AccessioniPrimary (citable) accession number: P0C7M6
Secondary accession number(s): B2RUV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: June 8, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.