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P0C7J3 (XANB_XANCP) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xanthan biosynthesis protein XanB

Including the following 2 domains:

  1. Mannose-6-phosphate isomerase
    EC=5.3.1.8
    Alternative name(s):
    Phosphohexomutase
    Phosphomannose isomerase
    Short name=PMI
  2. Mannose-1-phosphate guanylyl transferase
    EC=2.7.7.13
    Alternative name(s):
    GDP-mannose pyrophosphorylase
    Short name=GMP
    Short name=GMPP
Gene names
Name:xanB
Ordered Locus Names:XCC0625
OrganismXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568) [Reference proteome] [HAMAP]
Taxonomic identifier190485 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in xanthan production By similarity.

Catalytic activity

D-mannose 6-phosphate = D-fructose 6-phosphate.

GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.

Sequence similarities

Belongs to the mannose-6-phosphate isomerase type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 467467Xanthan biosynthesis protein XanB
PRO_0000194252

Sequences

Sequence LengthMass (Da)Tools
P0C7J3 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 77C8B346D7F25E3B

FASTA46750,962
        10         20         30         40         50         60 
MSDVLPIILS GGSGTRLWPL SRESYPKQFL PLVGEHSMLQ ATWLRSAPVA AHAPIVVANE 

        70         80         90        100        110        120 
EHRFMAAEQL QQLGVKPSAI LLEPKGRNTA PAIAVAALEA TRNGGDPLLL VLPSDHVIRD 

       130        140        150        160        170        180 
EAAFQAAVTV AAAAAEQGKL VTFGIKPTAP ETGYGYIKAG VGTGATAVER FVEKPDLATA 

       190        200        210        220        230        240 
QGYLASGEYY WNSGMFLFRA SRYLEELRKF QPAIADACQK AWEGGKRDAD FTRLDKDAFA 

       250        260        270        280        290        300 
SSPSDSIDYA VMEKTADAVV VPLDAGWNDV GSWSSLLDVS EQDGQGNAHH GDVIQLDCKN 

       310        320        330        340        350        360 
TYAYGSRLIA MVGLENVVVV ETDDAVLVGH RDRIQEVKEV VSQIKSAGRS EATWHRKVYR 

       370        380        390        400        410        420 
PWGAYDSIDM GQRFQVKRIT VKPGATLSLQ MHHHRAEHWI VVSGTAEVTR GEEVLLLTEN 

       430        440        450        460 
QSTYIPLGVT HRLKNPGKLP LELIEVQSGS YLGEDDIVRF EDTYGRT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008922 Genomic DNA. Translation: AAM39941.1.
RefSeqNP_636017.1. NC_003902.1.

3D structure databases

ProteinModelPortalP0C7J3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190485.XCC0625.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM39941; AAM39941; XCC0625.
GeneID1000899.
KEGGxcc:XCC0625.
PATRIC24071902. VBIXanCam115730_0686.

Phylogenomic databases

eggNOGCOG0662.
HOGENOMHOG000153549.
KOK16011.
OMAIYAACEQ.
OrthoDBEOG6X3W6T.

Enzyme and pathway databases

BioCycXCAM190485:GIXZ-625-MONOMER.
UniPathwayUPA00126; UER00423.
UPA00126; UER00930.

Family and domain databases

Gene3D2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamPF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMSSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsTIGR01479. GMP_PMI. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXANB_XANCP
AccessionPrimary (citable) accession number: P0C7J3
Secondary accession number(s): P29956, Q93S98
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: June 11, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways