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P0C7J3

- XANB_XANCP

UniProt

P0C7J3 - XANB_XANCP

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Protein

Xanthan biosynthesis protein XanB

Gene

xanB

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in xanthan production.By similarity

Catalytic activityi

D-mannose 6-phosphate = D-fructose 6-phosphate.
GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

Pathwayi

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. mannose-1-phosphate guanylyltransferase activity Source: UniProtKB-EC
  3. mannose-6-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. GDP-mannose biosynthetic process Source: UniProtKB-UniPathway
  2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Nucleotidyltransferase, Transferase

Keywords - Biological processi

Exopolysaccharide synthesis, Lipopolysaccharide biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciXCAM190485:GIXZ-625-MONOMER.
UniPathwayiUPA00126; UER00423.
UPA00126; UER00930.

Names & Taxonomyi

Protein namesi
Recommended name:
Xanthan biosynthesis protein XanB
Including the following 2 domains:
Mannose-6-phosphate isomerase (EC:5.3.1.8)
Alternative name(s):
Phosphohexomutase
Phosphomannose isomerase
Short name:
PMI
Mannose-1-phosphate guanylyl transferase (EC:2.7.7.13)
Alternative name(s):
GDP-mannose pyrophosphorylase
Short name:
GMP
Short name:
GMPP
Gene namesi
Name:xanB
Ordered Locus Names:XCC0625
OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Taxonomic identifieri190485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000001010: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Xanthan biosynthesis protein XanBPRO_0000194252Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi190485.XCC0625.

Structurei

3D structure databases

ProteinModelPortaliP0C7J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0662.
HOGENOMiHOG000153549.
KOiK16011.
OMAiIYAACEQ.
OrthoDBiEOG6X3W6T.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.

Sequencei

Sequence statusi: Complete.

P0C7J3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDVLPIILS GGSGTRLWPL SRESYPKQFL PLVGEHSMLQ ATWLRSAPVA
60 70 80 90 100
AHAPIVVANE EHRFMAAEQL QQLGVKPSAI LLEPKGRNTA PAIAVAALEA
110 120 130 140 150
TRNGGDPLLL VLPSDHVIRD EAAFQAAVTV AAAAAEQGKL VTFGIKPTAP
160 170 180 190 200
ETGYGYIKAG VGTGATAVER FVEKPDLATA QGYLASGEYY WNSGMFLFRA
210 220 230 240 250
SRYLEELRKF QPAIADACQK AWEGGKRDAD FTRLDKDAFA SSPSDSIDYA
260 270 280 290 300
VMEKTADAVV VPLDAGWNDV GSWSSLLDVS EQDGQGNAHH GDVIQLDCKN
310 320 330 340 350
TYAYGSRLIA MVGLENVVVV ETDDAVLVGH RDRIQEVKEV VSQIKSAGRS
360 370 380 390 400
EATWHRKVYR PWGAYDSIDM GQRFQVKRIT VKPGATLSLQ MHHHRAEHWI
410 420 430 440 450
VVSGTAEVTR GEEVLLLTEN QSTYIPLGVT HRLKNPGKLP LELIEVQSGS
460
YLGEDDIVRF EDTYGRT
Length:467
Mass (Da):50,962
Last modified:May 20, 2008 - v1
Checksum:i77C8B346D7F25E3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008922 Genomic DNA. Translation: AAM39941.1.
RefSeqiNP_636017.1. NC_003902.1.

Genome annotation databases

EnsemblBacteriaiAAM39941; AAM39941; XCC0625.
GeneIDi1000899.
KEGGixcc:XCC0625.
PATRICi24071902. VBIXanCam115730_0686.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008922 Genomic DNA. Translation: AAM39941.1 .
RefSeqi NP_636017.1. NC_003902.1.

3D structure databases

ProteinModelPortali P0C7J3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190485.XCC0625.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM39941 ; AAM39941 ; XCC0625 .
GeneIDi 1000899.
KEGGi xcc:XCC0625.
PATRICi 24071902. VBIXanCam115730_0686.

Phylogenomic databases

eggNOGi COG0662.
HOGENOMi HOG000153549.
KOi K16011.
OMAi IYAACEQ.
OrthoDBi EOG6X3W6T.

Enzyme and pathway databases

UniPathwayi UPA00126 ; UER00423 .
UPA00126 ; UER00930 .
BioCyci XCAM190485:GIXZ-625-MONOMER.

Family and domain databases

Gene3Di 2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProi IPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view ]
Pfami PF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR01479. GMP_PMI. 1 hit.
ProtoNeti Search...

Entry informationi

Entry nameiXANB_XANCP
AccessioniPrimary (citable) accession number: P0C7J3
Secondary accession number(s): P29956, Q93S98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzyme, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3