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P0C7J3

- XANB_XANCP

UniProt

P0C7J3 - XANB_XANCP

Protein

Xanthan biosynthesis protein XanB

Gene

xanB

Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Involved in xanthan production.By similarity

    Catalytic activityi

    D-mannose 6-phosphate = D-fructose 6-phosphate.
    GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

    Pathwayi

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW
    2. mannose-1-phosphate guanylyltransferase activity Source: UniProtKB-EC
    3. mannose-6-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. GDP-mannose biosynthetic process Source: UniProtKB-UniPathway
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase, Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Exopolysaccharide synthesis, Lipopolysaccharide biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciXCAM190485:GIXZ-625-MONOMER.
    UniPathwayiUPA00126; UER00423.
    UPA00126; UER00930.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xanthan biosynthesis protein XanB
    Including the following 2 domains:
    Mannose-6-phosphate isomerase (EC:5.3.1.8)
    Alternative name(s):
    Phosphohexomutase
    Phosphomannose isomerase
    Short name:
    PMI
    Mannose-1-phosphate guanylyl transferase (EC:2.7.7.13)
    Alternative name(s):
    GDP-mannose pyrophosphorylase
    Short name:
    GMP
    Short name:
    GMPP
    Gene namesi
    Name:xanB
    Ordered Locus Names:XCC0625
    OrganismiXanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)
    Taxonomic identifieri190485 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001010: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 467467Xanthan biosynthesis protein XanBPRO_0000194252Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi190485.XCC0625.

    Structurei

    3D structure databases

    ProteinModelPortaliP0C7J3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0662.
    HOGENOMiHOG000153549.
    KOiK16011.
    OMAiIYAACEQ.
    OrthoDBiEOG6X3W6T.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    3.90.550.10. 1 hit.
    InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
    IPR001538. Man6P_isomerase-2_C.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF01050. MannoseP_isomer. 1 hit.
    PF00483. NTP_transferase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51182. SSF51182. 1 hit.
    SSF53448. SSF53448. 1 hit.
    TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0C7J3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDVLPIILS GGSGTRLWPL SRESYPKQFL PLVGEHSMLQ ATWLRSAPVA    50
    AHAPIVVANE EHRFMAAEQL QQLGVKPSAI LLEPKGRNTA PAIAVAALEA 100
    TRNGGDPLLL VLPSDHVIRD EAAFQAAVTV AAAAAEQGKL VTFGIKPTAP 150
    ETGYGYIKAG VGTGATAVER FVEKPDLATA QGYLASGEYY WNSGMFLFRA 200
    SRYLEELRKF QPAIADACQK AWEGGKRDAD FTRLDKDAFA SSPSDSIDYA 250
    VMEKTADAVV VPLDAGWNDV GSWSSLLDVS EQDGQGNAHH GDVIQLDCKN 300
    TYAYGSRLIA MVGLENVVVV ETDDAVLVGH RDRIQEVKEV VSQIKSAGRS 350
    EATWHRKVYR PWGAYDSIDM GQRFQVKRIT VKPGATLSLQ MHHHRAEHWI 400
    VVSGTAEVTR GEEVLLLTEN QSTYIPLGVT HRLKNPGKLP LELIEVQSGS 450
    YLGEDDIVRF EDTYGRT 467
    Length:467
    Mass (Da):50,962
    Last modified:May 20, 2008 - v1
    Checksum:i77C8B346D7F25E3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008922 Genomic DNA. Translation: AAM39941.1.
    RefSeqiNP_636017.1. NC_003902.1.
    WP_011035868.1. NC_003902.1.

    Genome annotation databases

    EnsemblBacteriaiAAM39941; AAM39941; XCC0625.
    GeneIDi1000899.
    KEGGixcc:XCC0625.
    PATRICi24071902. VBIXanCam115730_0686.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008922 Genomic DNA. Translation: AAM39941.1 .
    RefSeqi NP_636017.1. NC_003902.1.
    WP_011035868.1. NC_003902.1.

    3D structure databases

    ProteinModelPortali P0C7J3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190485.XCC0625.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM39941 ; AAM39941 ; XCC0625 .
    GeneIDi 1000899.
    KEGGi xcc:XCC0625.
    PATRICi 24071902. VBIXanCam115730_0686.

    Phylogenomic databases

    eggNOGi COG0662.
    HOGENOMi HOG000153549.
    KOi K16011.
    OMAi IYAACEQ.
    OrthoDBi EOG6X3W6T.

    Enzyme and pathway databases

    UniPathwayi UPA00126 ; UER00423 .
    UPA00126 ; UER00930 .
    BioCyci XCAM190485:GIXZ-625-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    3.90.550.10. 1 hit.
    InterProi IPR006375. Man1P_GuaTrfase/Man6P_Isoase.
    IPR001538. Man6P_isomerase-2_C.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF01050. MannoseP_isomer. 1 hit.
    PF00483. NTP_transferase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51182. SSF51182. 1 hit.
    SSF53448. SSF53448. 1 hit.
    TIGRFAMsi TIGR01479. GMP_PMI. 1 hit.
    ProtoNeti Search...

    Entry informationi

    Entry nameiXANB_XANCP
    AccessioniPrimary (citable) accession number: P0C7J3
    Secondary accession number(s): P29956, Q93S98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Multifunctional enzyme, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3