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P0C7B6

- GLNA2_DICDI

UniProt

P0C7B6 - GLNA2_DICDI

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Protein
Type-1 glutamine synthetase 2
Gene
glnA2, DDB_G0295755
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Type-1 glutamine synthetase 2 (EC:6.3.1.2)
Short name:
Type-1 GS 2
Alternative name(s):
Type-1 glutamate--ammonia ligase 2
Gene namesi
Name:glnA2
ORF Names:DDB_G0295755
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0295755. glnA2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 521521Type-1 glutamine synthetase 2
PRO_0000330937Add
BLAST

Proteomic databases

PRIDEiP0C7B6.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 6059Asn-rich
Add
BLAST
Compositional biasi360 – 3634Poly-Leu

Sequence similaritiesi

Phylogenomic databases

OMAiLFHVDSE.
PhylomeDBiP0C7B6.

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.

Sequencei

Sequence statusi: Complete.

P0C7B6-1 [UniParc]FASTAAdd to Basket

« Hide

MNKLVNKNIF INKNNSLKNF VNNYSTKTNN NNNNIFNKNK NDLKSFSSSS    50
KLNNNNNNNN KYEESKLMNA EDLILNQIKI SKSPFVKIAG SDIDGILRGK 100
YLDKSKFESS IKKGLGFCSV IFGWDSSDSA YDNVKFTGNH TGYPDMGARP 150
DLSTFRTIPW EYDVPLFLMD FIGTNGEPLP ICPRSTLKKV IKKCHEHQFD 200
PVQGMEFEWY NYSENNKSLL NKNFSNLEPL SNGMFGYSLL RTSQNSEFMN 250
SLAELQGFGV PLEGLHTETG PGVYEAAIRF STALESADRA ILFKHCTKEI 300
ASLQGIMASF MAKPFKDLPG CSGHMHQNFN CLKTGKNLFL DESDPNHMSD 350
IFKSFVAGQL LLLPEFLPFF APTINSYKRL VDGYWAPTTP TWGMDNRTVA 400
LRIIKGGKAT RSEFRVTGSD VNPYISIAAS FAAGLYGVIN KLELKQKPII 450
GNSYDLYKKG LVERLPRSLA ESTELLSKSK IAKEYLGEEF VDHFVETRRW 500
EYRQFNHQVH KWELERYLEI I 521
Length:521
Mass (Da):59,201
Last modified:April 29, 2008 - v1
Checksum:iE4E77C3AEB67391A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000135 Genomic DNA. Translation: EEU04062.1.
RefSeqiXP_002649114.1. XM_002649068.1.

Genome annotation databases

EnsemblProtistsiDDB0252590; DDB0252590; DDB_G0295755.
GeneIDi8627058.
KEGGiddi:DDB_G0295755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000135 Genomic DNA. Translation: EEU04062.1 .
RefSeqi XP_002649114.1. XM_002649068.1.

3D structure databases

ModBasei Search...

Proteomic databases

PRIDEi P0C7B6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0252590 ; DDB0252590 ; DDB_G0295755 .
GeneIDi 8627058.
KEGGi ddi:DDB_G0295755.

Organism-specific databases

dictyBasei DDB_G0295755. glnA2.

Phylogenomic databases

OMAi LFHVDSE.
PhylomeDBi P0C7B6.

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  2. Bienvenut W.V., Veltman D.M., Insall R.H.
    Submitted (JAN-2010) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 88-98; 280-289 AND 468-478, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiGLNA2_DICDI
AccessioniPrimary (citable) accession number: P0C7B6
Secondary accession number(s): C7G063
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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