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P0C7B6 (GLNA2_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-1 glutamine synthetase 2

Short name=Type-1 GS 2
EC=6.3.1.2
Alternative name(s):
Type-1 glutamate--ammonia ligase 2
Gene names
Name:glnA2
ORF Names:DDB_G0295755
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length521 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 521521Type-1 glutamine synthetase 2
PRO_0000330937

Regions

Compositional bias2 – 6059Asn-rich
Compositional bias360 – 3634Poly-Leu

Sequences

Sequence LengthMass (Da)Tools
P0C7B6 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: E4E77C3AEB67391A

FASTA52159,201
        10         20         30         40         50         60 
MNKLVNKNIF INKNNSLKNF VNNYSTKTNN NNNNIFNKNK NDLKSFSSSS KLNNNNNNNN 

        70         80         90        100        110        120 
KYEESKLMNA EDLILNQIKI SKSPFVKIAG SDIDGILRGK YLDKSKFESS IKKGLGFCSV 

       130        140        150        160        170        180 
IFGWDSSDSA YDNVKFTGNH TGYPDMGARP DLSTFRTIPW EYDVPLFLMD FIGTNGEPLP 

       190        200        210        220        230        240 
ICPRSTLKKV IKKCHEHQFD PVQGMEFEWY NYSENNKSLL NKNFSNLEPL SNGMFGYSLL 

       250        260        270        280        290        300 
RTSQNSEFMN SLAELQGFGV PLEGLHTETG PGVYEAAIRF STALESADRA ILFKHCTKEI 

       310        320        330        340        350        360 
ASLQGIMASF MAKPFKDLPG CSGHMHQNFN CLKTGKNLFL DESDPNHMSD IFKSFVAGQL 

       370        380        390        400        410        420 
LLLPEFLPFF APTINSYKRL VDGYWAPTTP TWGMDNRTVA LRIIKGGKAT RSEFRVTGSD 

       430        440        450        460        470        480 
VNPYISIAAS FAAGLYGVIN KLELKQKPII GNSYDLYKKG LVERLPRSLA ESTELLSKSK 

       490        500        510        520 
IAKEYLGEEF VDHFVETRRW EYRQFNHQVH KWELERYLEI I 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]Bienvenut W.V., Veltman D.M., Insall R.H.
Submitted (JAN-2010) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 88-98; 280-289 AND 468-478, IDENTIFICATION BY MASS SPECTROMETRY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000135 Genomic DNA. Translation: EEU04062.1.
RefSeqXP_002649114.1. XM_002649068.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP0C7B6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0252590; DDB0252590; DDB_G0295755.
GeneID8627058.
KEGGddi:DDB_G0295755.

Organism-specific databases

dictyBaseDDB_G0295755. glnA2.

Phylogenomic databases

OMALFHVDSE.
PhylomeDBP0C7B6.

Family and domain databases

Gene3D3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLNA2_DICDI
AccessionPrimary (citable) accession number: P0C7B6
Secondary accession number(s): C7G063
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase