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P0C7B6

- GLNA2_DICDI

UniProt

P0C7B6 - GLNA2_DICDI

Protein

Type-1 glutamine synthetase 2

Gene

glnA2

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-1 glutamine synthetase 2 (EC:6.3.1.2)
    Short name:
    Type-1 GS 2
    Alternative name(s):
    Type-1 glutamate--ammonia ligase 2
    Gene namesi
    Name:glnA2
    ORF Names:DDB_G0295755
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0295755. glnA2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 521521Type-1 glutamine synthetase 2PRO_0000330937Add
    BLAST

    Proteomic databases

    PRIDEiP0C7B6.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi2 – 6059Asn-richAdd
    BLAST
    Compositional biasi360 – 3634Poly-Leu

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Phylogenomic databases

    OMAiLFHVDSE.
    PhylomeDBiP0C7B6.

    Family and domain databases

    Gene3Di3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0C7B6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKLVNKNIF INKNNSLKNF VNNYSTKTNN NNNNIFNKNK NDLKSFSSSS    50
    KLNNNNNNNN KYEESKLMNA EDLILNQIKI SKSPFVKIAG SDIDGILRGK 100
    YLDKSKFESS IKKGLGFCSV IFGWDSSDSA YDNVKFTGNH TGYPDMGARP 150
    DLSTFRTIPW EYDVPLFLMD FIGTNGEPLP ICPRSTLKKV IKKCHEHQFD 200
    PVQGMEFEWY NYSENNKSLL NKNFSNLEPL SNGMFGYSLL RTSQNSEFMN 250
    SLAELQGFGV PLEGLHTETG PGVYEAAIRF STALESADRA ILFKHCTKEI 300
    ASLQGIMASF MAKPFKDLPG CSGHMHQNFN CLKTGKNLFL DESDPNHMSD 350
    IFKSFVAGQL LLLPEFLPFF APTINSYKRL VDGYWAPTTP TWGMDNRTVA 400
    LRIIKGGKAT RSEFRVTGSD VNPYISIAAS FAAGLYGVIN KLELKQKPII 450
    GNSYDLYKKG LVERLPRSLA ESTELLSKSK IAKEYLGEEF VDHFVETRRW 500
    EYRQFNHQVH KWELERYLEI I 521
    Length:521
    Mass (Da):59,201
    Last modified:April 29, 2008 - v1
    Checksum:iE4E77C3AEB67391A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000135 Genomic DNA. Translation: EEU04062.1.
    RefSeqiXP_002649114.1. XM_002649068.1.

    Genome annotation databases

    EnsemblProtistsiDDB0252590; DDB0252590; DDB_G0295755.
    GeneIDi8627058.
    KEGGiddi:DDB_G0295755.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000135 Genomic DNA. Translation: EEU04062.1 .
    RefSeqi XP_002649114.1. XM_002649068.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P0C7B6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0252590 ; DDB0252590 ; DDB_G0295755 .
    GeneIDi 8627058.
    KEGGi ddi:DDB_G0295755.

    Organism-specific databases

    dictyBasei DDB_G0295755. glnA2.

    Phylogenomic databases

    OMAi LFHVDSE.
    PhylomeDBi P0C7B6.

    Family and domain databases

    Gene3Di 3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    2. Bienvenut W.V., Veltman D.M., Insall R.H.
      Submitted (JAN-2010) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 88-98; 280-289 AND 468-478, IDENTIFICATION BY MASS SPECTROMETRY.

    Entry informationi

    Entry nameiGLNA2_DICDI
    AccessioniPrimary (citable) accession number: P0C7B6
    Secondary accession number(s): C7G063
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3