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Protein

Super small secreted glycoprotein

Gene

GP

Organism
Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Super small secreted glycoprotein
Short name:
SsGP
Gene namesi
Name:GP
OrganismiReston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus)
Taxonomic identifieri386032 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesMononegaviralesFiloviridaeEbolavirus
Virus hostiEpomops franqueti (Franquet's epauleted fruit bat) [TaxID: 77231]
Homo sapiens (Human) [TaxID: 9606]
Myonycteris torquata (Little collared fruit bat) [TaxID: 77243]
Sus scrofa (Pig) [TaxID: 9823]
Proteomesi
  • UP000138664 Componenti: Genome
  • UP000007207 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_000039149834 – 332Super small secreted glycoproteinAdd BLAST299

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi41N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Disulfide bondi54InterchainBy similarity
Disulfide bondi109 ↔ 136By similarity
Disulfide bondi122 ↔ 148By similarity
Glycosylationi205N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi229N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi239N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi258N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi269N-linked (GlcNAc...) asparagine; by hostSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

SMRiP0C771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the filoviruses glycoprotein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiVOG090000CW.

Family and domain databases

InterProiView protein in InterPro
IPR014625. GPC_FiloV.
IPR002561. GPC_filovir-type_extra_dom.
PfamiView protein in Pfam
PF01611. Filo_glycop. 1 hit.
PIRSFiPIRSF036874. GPC_FiloV. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSGYQLLQL PRERFRKTSF LVWVIILFQR AISMPLGIVT NSTLKATEID
60 70 80 90 100
QLVCRDKLSS TSQLKSVGLN LEGNGIATDV PSATKRWGFR SGVPPKVVSY
110 120 130 140 150
EAGEWAENCY NLEIKKSDGS ECLPLPPDGV RGFPRCRYVH KVQGTGPCPG
160 170 180 190 200
DLAFHKNGAF FLYDRLASTV IYRGTTFAEG VVAFLILSEP KKHFWKATPA
210 220 230 240 250
HEPVNTTDDS TSYYMTLTLS YEMSNFGGNE SNTLFKVDNH TYVQLDRPHT
260 270 280 290 300
PQFLVQLNET LRRNNRLSNS TGRLTWTLDP KIEPDVGEWA FWETKKKLFP
310 320 330
TTSWRKLAFP NSINPHQQLL RSEPGGNCPR KN
Length:332
Mass (Da):37,481
Last modified:February 9, 2010 - v1
Checksum:iAB4A4D5AA957EE71
GO

RNA editingi

Edited at position 295.1 Publication
Partially edited. RNA editing at this position consists of an insertion of one or two adenine nucleotides. The sequence displayed here is the super small secreted glycoprotein ssGP, derived from the +2A edited RNA. The unedited RNA gives rise to the small secreted glycoprotein sGP (AC Q66800), the +1A edited RNA gives rise to the full-length transmembrane glycoprotein GP (AC Q66799).

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23152 Genomic RNA. No translation available.
AF034645 Genomic RNA. No translation available.
AF522874 Genomic RNA. No translation available.
AY769362 Genomic RNA. No translation available.

Keywords - Coding sequence diversityi

RNA editing

Similar proteinsi

Entry informationi

Entry nameiVSSGP_EBORR
AccessioniPrimary (citable) accession number: P0C771
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: February 9, 2010
Last modified: September 27, 2017
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families