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P0C770 (VSSGP_EBORE) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Super small secreted glycoprotein

Short name=SsGP
Gene names
Name:GP
OrganismReston ebolavirus (strain Philippines-96) (REBOV) (Reston Ebola virus) [Complete proteome]
Taxonomic identifier129003 [NCBI]
Taxonomic lineageVirusesssRNA negative-strand virusesMononegaviralesFiloviridaeEbolavirus
Virus hostHomo sapiens (Human) [TaxID: 9606]
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) [TaxID: 9541]
Pteropodinae [TaxID: 77225]
Sus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the filoviruses glycoprotein family.

RNA editing

Edited at position 296.
Partially edited. RNA editing at this position consists of an insertion of one or two adenine nucleotides. The sequence displayed here is the super small secreted glycoprotein ssGP, derived from the +2A edited RNA. The unedited RNA gives rise to the small secreted glycoprotein sGP (AC Q91DD7), the +1A edited RNA gives rise to the full-length transmembrane glycoprotein GP (AC Q91DD8).

Ontologies

Keywords
   Cellular componentSecreted
   Coding sequence diversityRNA editing
   DomainSignal
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333 Potential
Chain34 – 332299Super small secreted glycoprotein
PRO_0000391495

Amino acid modifications

Glycosylation411N-linked (GlcNAc...); by host Potential
Glycosylation2051N-linked (GlcNAc...); by host Potential
Glycosylation2391N-linked (GlcNAc...); by host Potential
Glycosylation2581N-linked (GlcNAc...); by host Potential
Glycosylation2691N-linked (GlcNAc...); by host Potential
Disulfide bond54Interchain By similarity
Disulfide bond109 ↔ 136 By similarity
Disulfide bond122 ↔ 148 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C770 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: D1AFC1BD29D68F35

FASTA33237,496
        10         20         30         40         50         60 
MGSGYQLLQL PRERFRKTSF LVWVIILFQR AISMPLGIVT NSTLKATEID QLVCRDKLSS 

        70         80         90        100        110        120 
TSQLKSVGLN LEGNGIATDV PSATKRWGFR SGVPPKVVSY EAGEWAENCY NLEIKKSDGS 

       130        140        150        160        170        180 
ECLPLPPDGV RGFPRCRYVH KVQGTGPCPG DLAFHKNGAF FLYDRLASTV IYRGTTFAEG 

       190        200        210        220        230        240 
VIAFLILSEP KKHFWKATPA HEPVNTTDDS TSYYMTLTLS YEMSNFGGEE SNTLFKVDNH 

       250        260        270        280        290        300 
TYVQLDRPHT PQFLVQLNET LRRNNRLSNS TGRLTWTVDP KIEPDVGEWA FWETKKKLFP 

       310        320        330 
TTSWRKLAFP NSINPHQQLL RSEPGGNCPR KN 

« Hide

References

[1]"Genome structure of Ebola virus subtype Reston: differences among Ebola subtypes."
Ikegami T., Calaor A.B., Miranda M.E., Niikura M., Saijo M., Kurane I., Yoshikawa Y., Morikawa S.
Arch. Virol. 146:2021-2027(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB050936 Genomic RNA. No translation available.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002561. GPC_filovir-type_extra_dom.
[Graphical view]
PfamPF01611. Filo_glycop. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVSSGP_EBORE
AccessionPrimary (citable) accession number: P0C770
Entry history
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: February 9, 2010
Last modified: December 11, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families