ID NSP6_ROTH3 Reviewed; 74 AA. AC P0C713; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 14-APR-2009, sequence version 1. DT 14-DEC-2022, entry version 27. DE RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093}; DE Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093}; OS Rotavirus A (strain RVA/Human/Japan/AU-1/1982/G3P3[9]) (RV-A). OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A. OX NCBI_TaxID=39013; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX PubMed=9598939; RX DOI=10.1002/(sici)1096-9071(199806)55:2<168::aid-jmv14>3.0.co;2-e; RA Wu H., Taniguchi K., Urasawa T., Urasawa S.; RT "Serological and genomic characterization of human rotaviruses detected in RT China."; RL J. Med. Virol. 55:168-176(1998). CC -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}. CC Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in CC spherical cytoplasmic structures, called viral factories, that appear CC early after infection and are the site of viral replication and CC packaging. {ECO:0000255|HAMAP-Rule:MF_04093}. CC -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB008656; -; NOT_ANNOTATED_CDS; mRNA. DR SMR; P0C713; -. DR Proteomes; UP000001454; Genome. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell. DR HAMAP; MF_04093; ROTA_NSP6; 1. DR InterPro; IPR006950; Rotavirus_NSP6. DR Pfam; PF04866; Rota_NS6; 1. PE 3: Inferred from homology; KW Host cytoplasm; Host mitochondrion. FT CHAIN 1..74 FT /note="Non-structural protein 6" FT /id="PRO_0000369518" SQ SEQUENCE 74 AA; 8839 MW; 5AE7E36030B08D82 CRC64; MNHLQQRQLF LENLLVGVNN TFHQMQKRSV STCCQSLQKI LDHLILLQTI HSPVFRLDRM QLRQMQTLAC LWIH //