ID NSP6_ROT41 Reviewed; 96 AA. AC P0C710; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 14-APR-2009, sequence version 1. DT 14-DEC-2022, entry version 26. DE RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093}; DE Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093}; OS Rotavirus A (isolate RVA/Human/Belgium/B4106/2000/G3P11[14]) (RV-A) OS (Rotavirus A (isolate B4106)). OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A. OX NCBI_TaxID=578843; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC RNA]. RX PubMed=16571797; DOI=10.1128/jvi.80.8.3801-3810.2006; RA Matthijnssens J., Rahman M., Martella V., Xuelei Y., De Vos S., RA De Leener K., Ciarlet M., Buonavoglia C., Van Ranst M.; RT "Full genomic analysis of human rotavirus strain B4106 and lapine rotavirus RT strain 30/96 provides evidence for interspecies transmission."; RL J. Virol. 80:3801-3810(2006). CC -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}. CC Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in CC spherical cytoplasmic structures, called viral factories, that appear CC early after infection and are the site of viral replication and CC packaging. {ECO:0000255|HAMAP-Rule:MF_04093}. CC -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY740731; -; NOT_ANNOTATED_CDS; Genomic_RNA. DR Proteomes; UP000008655; Genome. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell. DR HAMAP; MF_04093; ROTA_NSP6; 1. DR InterPro; IPR006950; Rotavirus_NSP6. DR Pfam; PF04866; Rota_NS6; 1. PE 3: Inferred from homology; KW Host cytoplasm; Host mitochondrion. FT CHAIN 1..96 FT /note="Non-structural protein 6" FT /id="PRO_0000369509" SQ SEQUENCE 96 AA; 11557 MW; 3C37D0A267D04847 CRC64; MNHRQQRQLF LENLLVGMNC MFHQMQKRSI NTCCQNLQKI LDRLILLQTI HSPAFRLDRM QLRQMQTLAC LWIHQHNHDH QVMLGAIKWI SPLTKQ //