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P0C6Z2 (NSP6_ROTBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-structural protein 6

Short name=NSP6
OrganismRotavirus A (strain Cow/United Kingdom/UK/1975 G6-P7[5]-I2-R2-C2-M2-A3-N2-T7-E2-H3) (RV-A) [Complete proteome]
Taxonomic identifier10934 [NCBI]
Taxonomic lineageVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirusRotavirus A
Virus hostBos taurus (Bovine) [TaxID: 9913]

Protein attributes

Sequence length98 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with NSP5 By similarity.

Subcellular location

Host cytoplasm. Note: Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging. Ref.2

Sequence similarities

Belongs to the rotavirus A NSP6 family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9898Non-structural protein 6
PRO_0000369514

Sequences

Sequence LengthMass (Da)Tools
P0C6Z2 [UniParc].

Last modified April 14, 2009. Version 1.
Checksum: C9752DA122E325E5

FASTA9811,693
        10         20         30         40         50         60 
MNHLQQRQLF LENLLVGVNN MFHQMQKRPV NTCCRSLQKI LDHLILLQTI HSPAFRLDQM 

        70         80         90 
QLRQMQTLAC LWIHQYNHDH QVTLGAIKWI SPLIKELK 

« Hide

References

[1]"Structural homologies between RNA gene segments 10 and 11 from UK bovine, simian SA11, and human Wa rotaviruses."
Ward C.W., Azad A.A., Dyall-Smith M.L.
Virology 144:328-336(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Characterization of the NSP6 protein product of rotavirus gene 11."
Rainsford E.W., McCrae M.A.
Virus Res. 130:193-201(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION, SUBCELLULAR LOCATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
K03385 Genomic RNA. No translation available.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR006950. Rotavirus_NSP6.
[Graphical view]
PfamPF04866. Rota_NS6. 1 hit.
[Graphical view]
ProDomPD008065. Rota_NS6. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNSP6_ROTBU
AccessionPrimary (citable) accession number: P0C6Z2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families