Reviewed,
UniProtKB/Swiss-Prot P0C6T2 (OST4_HUMAN)
Last modified
May 26, 2009.
Version 7.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 37 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | May be involved in N-glycosylation through its association with N-oligosaccharyl transferase By similarity. |
| Subunit structure | Component of the oligosaccharyl transferase (OST) complex By similarity. OST seems to exist in different forms which contain at least RPN1/ribophorin-1, RPN2/ribophorin-2, OST48, DAD1, and either STT3A or STT3B By similarity. |
| Subcellular location | Membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Belongs to the OST4 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane |
| Domain | Transmembrane |
| Gene Ontology (GO) | |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.  Wilson R.K.Nature 434:724-731(2005) [PubMed: 15815621] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| AC013403 Genomic DNA. No translation available. BC015653 mRNA. No translation available. | |
| IPI | IPI00913953. |
| RefSeq | NP_001128165.1. |
| UniGene | Hs.502948 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 100128731. |
| KEGG | hsa:100128731. |
Family and domain databases | |
| InterPro | IPR018943. Oligosaccaryltransferase. [Graphical view] |
| Pfam | PF10215. Ost4. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | OST4_HUMAN | ||||||||
| Accession | Primary (citable) accession number: P0C6T2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| Human chromosome 2 Human chromosome 2: entries, gene names and cross-references to MIM |
| SIMILARITY comments Index of protein domains and families |
