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P0C6A1

- GTR7_MOUSE

UniProt

P0C6A1 - GTR7_MOUSE

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Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene
Slc2a7
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei332 – 3321Monosaccharide By similarity

GO - Molecular functioni

  1. substrate-specific transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. carbohydrate transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 7
Alternative name(s):
Glucose transporter type 7
Short name:
GLUT-7
Gene namesi
Name:Slc2a7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:3650865. Slc2a7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei22 – 4221Helical; Reviewed predictionAdd
BLAST
Topological domaini43 – 7836Extracellular Reviewed predictionAdd
BLAST
Transmembranei79 – 9921Helical; Reviewed predictionAdd
BLAST
Topological domaini100 – 1078Cytoplasmic Reviewed prediction
Transmembranei108 – 12821Helical; Reviewed predictionAdd
BLAST
Topological domaini129 – 13810Extracellular Reviewed prediction
Transmembranei139 – 15921Helical; Reviewed predictionAdd
BLAST
Topological domaini160 – 17213Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei173 – 19321Helical; Reviewed predictionAdd
BLAST
Topological domaini194 – 1985Extracellular Reviewed prediction
Transmembranei199 – 21921Helical; Reviewed predictionAdd
BLAST
Topological domaini220 – 28263Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei283 – 30321Helical; Reviewed predictionAdd
BLAST
Topological domaini304 – 32219Extracellular Reviewed predictionAdd
BLAST
Transmembranei323 – 34321Helical; Reviewed predictionAdd
BLAST
Topological domaini344 – 3518Cytoplasmic Reviewed prediction
Transmembranei352 – 37221Helical; Reviewed predictionAdd
BLAST
Topological domaini373 – 3808Extracellular Reviewed prediction
Transmembranei381 – 40121Helical; Reviewed predictionAdd
BLAST
Topological domaini402 – 41615Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei417 – 43721Helical; Reviewed predictionAdd
BLAST
Topological domaini438 – 4469Extracellular Reviewed prediction
Transmembranei447 – 46721Helical; Reviewed predictionAdd
BLAST
Topological domaini468 – 51346Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 513513Solute carrier family 2, facilitated glucose transporter member 7PRO_0000317272Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi57 – 571N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP0C6A1.

Expressioni

Gene expression databases

GenevestigatoriP0C6A1.

Structurei

3D structure databases

ProteinModelPortaliP0C6A1.
SMRiP0C6A1. Positions 78-111.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni295 – 3017Monosaccharide binding By similarity

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
HOVERGENiHBG014816.
InParanoidiP0C6A1.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C6A1-1 [UniParc]FASTAAdd to Basket

« Hide

MEDKEIGTPL PLPHSEARLQ PTLVLTTLSA AFGSVFQYGY NIAVINTPHK    50
VFKSFYNDTH FERHGTFMDE STLLLLWSCT VSMFPLGGLL GSLVVGLMVN 100
KWGRKGTLLI NNVFAITSAV LMGVSKVARA FELIILSRVL VGICAGIAYS 150
TLPMYLGELA PQNLRGALGT MTEVFVIIGV LLAQIFSLQA ILGNATGWPI 200
LLALTGVPAV IQLLSLPFFP ESPRYTLIEK GDEETARQAL RRLRGQNYNV 250
EAEMEEMRTE ERTEQAEGRL SVLNLFTFRP LRWQLISIVV LMAGQQLSGI 300
NAVNYYADVI YTSAGVDPTQ SQYVTLGSGV INLVMTLVSA VIIERLGRRI 350
LLLSGYAICC SACLVLTVAL LLQSTAPELS YLSIVCVFSY IVGHSIGPSP 400
VPSVVRTEIV LQSSRTAAFT VDGAVHWLTN FIVGLTFPSI QVAIGAYSFL 450
VFAGVCILTA AYIYVVIPET KGRTFVEINC AFAKRNGVEF PEEKEVATAK 500
PHTPSLPTKE TAF 513
Length:513
Mass (Da):55,886
Last modified:February 5, 2008 - v1
Checksum:iC4FFBFE9EE8061B9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL606971 Genomic DNA. No translation available.
UniGeneiMm.359648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL606971 Genomic DNA. No translation available.
UniGenei Mm.359648.

3D structure databases

ProteinModelPortali P0C6A1.
SMRi P0C6A1. Positions 78-111.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P0C6A1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:3650865. Slc2a7.

Phylogenomic databases

eggNOGi COG0477.
HOVERGENi HBG014816.
InParanoidi P0C6A1.

Miscellaneous databases

PROi P0C6A1.
SOURCEi Search...

Gene expression databases

Genevestigatori P0C6A1.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
PRINTSi PR00171. SUGRTRNSPORT.
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00879. SP. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.

Entry informationi

Entry nameiGTR7_MOUSE
AccessioniPrimary (citable) accession number: P0C6A1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 3, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi