Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene

Slc2a7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei332 – 3321MonosaccharideBy similarity

GO - Molecular functioni

  1. substrate-specific transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. carbohydrate transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 7
Alternative name(s):
Glucose transporter type 7
Short name:
GLUT-7
Gene namesi
Name:Slc2a7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:3650865. Slc2a7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei22 – 4221HelicalSequence AnalysisAdd
BLAST
Topological domaini43 – 7836ExtracellularSequence AnalysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence AnalysisAdd
BLAST
Topological domaini100 – 1078CytoplasmicSequence Analysis
Transmembranei108 – 12821HelicalSequence AnalysisAdd
BLAST
Topological domaini129 – 13810ExtracellularSequence Analysis
Transmembranei139 – 15921HelicalSequence AnalysisAdd
BLAST
Topological domaini160 – 17213CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei173 – 19321HelicalSequence AnalysisAdd
BLAST
Topological domaini194 – 1985ExtracellularSequence Analysis
Transmembranei199 – 21921HelicalSequence AnalysisAdd
BLAST
Topological domaini220 – 28263CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei283 – 30321HelicalSequence AnalysisAdd
BLAST
Topological domaini304 – 32219ExtracellularSequence AnalysisAdd
BLAST
Transmembranei323 – 34321HelicalSequence AnalysisAdd
BLAST
Topological domaini344 – 3518CytoplasmicSequence Analysis
Transmembranei352 – 37221HelicalSequence AnalysisAdd
BLAST
Topological domaini373 – 3808ExtracellularSequence Analysis
Transmembranei381 – 40121HelicalSequence AnalysisAdd
BLAST
Topological domaini402 – 41615CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei417 – 43721HelicalSequence AnalysisAdd
BLAST
Topological domaini438 – 4469ExtracellularSequence Analysis
Transmembranei447 – 46721HelicalSequence AnalysisAdd
BLAST
Topological domaini468 – 51346CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 513513Solute carrier family 2, facilitated glucose transporter member 7PRO_0000317272Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi57 – 571N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP0C6A1.

Expressioni

Gene expression databases

GenevestigatoriP0C6A1.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni295 – 3017Monosaccharide bindingBy similarity

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
HOVERGENiHBG014816.
InParanoidiP0C6A1.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C6A1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKEIGTPL PLPHSEARLQ PTLVLTTLSA AFGSVFQYGY NIAVINTPHK
60 70 80 90 100
VFKSFYNDTH FERHGTFMDE STLLLLWSCT VSMFPLGGLL GSLVVGLMVN
110 120 130 140 150
KWGRKGTLLI NNVFAITSAV LMGVSKVARA FELIILSRVL VGICAGIAYS
160 170 180 190 200
TLPMYLGELA PQNLRGALGT MTEVFVIIGV LLAQIFSLQA ILGNATGWPI
210 220 230 240 250
LLALTGVPAV IQLLSLPFFP ESPRYTLIEK GDEETARQAL RRLRGQNYNV
260 270 280 290 300
EAEMEEMRTE ERTEQAEGRL SVLNLFTFRP LRWQLISIVV LMAGQQLSGI
310 320 330 340 350
NAVNYYADVI YTSAGVDPTQ SQYVTLGSGV INLVMTLVSA VIIERLGRRI
360 370 380 390 400
LLLSGYAICC SACLVLTVAL LLQSTAPELS YLSIVCVFSY IVGHSIGPSP
410 420 430 440 450
VPSVVRTEIV LQSSRTAAFT VDGAVHWLTN FIVGLTFPSI QVAIGAYSFL
460 470 480 490 500
VFAGVCILTA AYIYVVIPET KGRTFVEINC AFAKRNGVEF PEEKEVATAK
510
PHTPSLPTKE TAF
Length:513
Mass (Da):55,886
Last modified:February 5, 2008 - v1
Checksum:iC4FFBFE9EE8061B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA. No translation available.
UniGeneiMm.359648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA. No translation available.
UniGeneiMm.359648.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP0C6A1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:3650865. Slc2a7.

Phylogenomic databases

eggNOGiCOG0477.
HOVERGENiHBG014816.
InParanoidiP0C6A1.

Miscellaneous databases

PROiP0C6A1.
SOURCEiSearch...

Gene expression databases

GenevestigatoriP0C6A1.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.

Entry informationi

Entry nameiGTR7_MOUSE
AccessioniPrimary (citable) accession number: P0C6A1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 1, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.