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Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene

Slc2a7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei332MonosaccharideBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 7
Alternative name(s):
Glucose transporter type 7
Short name:
GLUT-7
Gene namesi
Name:Slc2a7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:3650865. Slc2a7.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21CytoplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 78ExtracellularSequence analysisAdd BLAST36
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 107CytoplasmicSequence analysis8
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Topological domaini129 – 138ExtracellularSequence analysis10
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 172CytoplasmicSequence analysisAdd BLAST13
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 198ExtracellularSequence analysis5
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Topological domaini220 – 282CytoplasmicSequence analysisAdd BLAST63
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Topological domaini304 – 322ExtracellularSequence analysisAdd BLAST19
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Topological domaini344 – 351CytoplasmicSequence analysis8
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Topological domaini373 – 380ExtracellularSequence analysis8
Transmembranei381 – 401HelicalSequence analysisAdd BLAST21
Topological domaini402 – 416CytoplasmicSequence analysisAdd BLAST15
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Topological domaini438 – 446ExtracellularSequence analysis9
Transmembranei447 – 467HelicalSequence analysisAdd BLAST21
Topological domaini468 – 513CytoplasmicSequence analysisAdd BLAST46

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172721 – 513Solute carrier family 2, facilitated glucose transporter member 7Add BLAST513

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi57N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP0C6A1.
PRIDEiP0C6A1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059106.

Structurei

3D structure databases

ProteinModelPortaliP0C6A1.
SMRiP0C6A1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni295 – 301Monosaccharide bindingBy similarity7

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
InParanoidiP0C6A1.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C6A1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKEIGTPL PLPHSEARLQ PTLVLTTLSA AFGSVFQYGY NIAVINTPHK
60 70 80 90 100
VFKSFYNDTH FERHGTFMDE STLLLLWSCT VSMFPLGGLL GSLVVGLMVN
110 120 130 140 150
KWGRKGTLLI NNVFAITSAV LMGVSKVARA FELIILSRVL VGICAGIAYS
160 170 180 190 200
TLPMYLGELA PQNLRGALGT MTEVFVIIGV LLAQIFSLQA ILGNATGWPI
210 220 230 240 250
LLALTGVPAV IQLLSLPFFP ESPRYTLIEK GDEETARQAL RRLRGQNYNV
260 270 280 290 300
EAEMEEMRTE ERTEQAEGRL SVLNLFTFRP LRWQLISIVV LMAGQQLSGI
310 320 330 340 350
NAVNYYADVI YTSAGVDPTQ SQYVTLGSGV INLVMTLVSA VIIERLGRRI
360 370 380 390 400
LLLSGYAICC SACLVLTVAL LLQSTAPELS YLSIVCVFSY IVGHSIGPSP
410 420 430 440 450
VPSVVRTEIV LQSSRTAAFT VDGAVHWLTN FIVGLTFPSI QVAIGAYSFL
460 470 480 490 500
VFAGVCILTA AYIYVVIPET KGRTFVEINC AFAKRNGVEF PEEKEVATAK
510
PHTPSLPTKE TAF
Length:513
Mass (Da):55,886
Last modified:February 5, 2008 - v1
Checksum:iC4FFBFE9EE8061B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA. No translation available.
UniGeneiMm.359648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA. No translation available.
UniGeneiMm.359648.

3D structure databases

ProteinModelPortaliP0C6A1.
SMRiP0C6A1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059106.

Proteomic databases

PaxDbiP0C6A1.
PRIDEiP0C6A1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:3650865. Slc2a7.

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
InParanoidiP0C6A1.

Miscellaneous databases

PROiP0C6A1.
SOURCEiSearch...

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGTR7_MOUSE
AccessioniPrimary (citable) accession number: P0C6A1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 30, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.