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P0C6A1

- GTR7_MOUSE

UniProt

P0C6A1 - GTR7_MOUSE

Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene

Slc2a7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei332 – 3321MonosaccharideBy similarity

    GO - Molecular functioni

    1. substrate-specific transmembrane transporter activity Source: InterPro

    GO - Biological processi

    1. carbohydrate transport Source: UniProtKB-KW

    Keywords - Biological processi

    Sugar transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Solute carrier family 2, facilitated glucose transporter member 7
    Alternative name(s):
    Glucose transporter type 7
    Short name:
    GLUT-7
    Gene namesi
    Name:Slc2a7
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:3650865. Slc2a7.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 513513Solute carrier family 2, facilitated glucose transporter member 7PRO_0000317272Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi57 – 571N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiP0C6A1.

    Expressioni

    Gene expression databases

    GenevestigatoriP0C6A1.

    Structurei

    3D structure databases

    ProteinModelPortaliP0C6A1.
    SMRiP0C6A1. Positions 78-111.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2121CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini43 – 7836ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini100 – 1078CytoplasmicSequence Analysis
    Topological domaini129 – 13810ExtracellularSequence Analysis
    Topological domaini160 – 17213CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini194 – 1985ExtracellularSequence Analysis
    Topological domaini220 – 28263CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini304 – 32219ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini344 – 3518CytoplasmicSequence Analysis
    Topological domaini373 – 3808ExtracellularSequence Analysis
    Topological domaini402 – 41615CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini438 – 4469ExtracellularSequence Analysis
    Topological domaini468 – 51346CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei22 – 4221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei79 – 9921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei108 – 12821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei139 – 15921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei173 – 19321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei199 – 21921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei283 – 30321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei323 – 34321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei352 – 37221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei381 – 40121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei417 – 43721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei447 – 46721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni295 – 3017Monosaccharide bindingBy similarity

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0477.
    HOVERGENiHBG014816.
    InParanoidiP0C6A1.

    Family and domain databases

    InterProiIPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view]
    PfamiPF00083. Sugar_tr. 1 hit.
    [Graphical view]
    PRINTSiPR00171. SUGRTRNSPORT.
    SUPFAMiSSF103473. SSF103473. 1 hit.
    TIGRFAMsiTIGR00879. SP. 1 hit.
    PROSITEiPS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0C6A1-1 [UniParc]FASTAAdd to Basket

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    MEDKEIGTPL PLPHSEARLQ PTLVLTTLSA AFGSVFQYGY NIAVINTPHK    50
    VFKSFYNDTH FERHGTFMDE STLLLLWSCT VSMFPLGGLL GSLVVGLMVN 100
    KWGRKGTLLI NNVFAITSAV LMGVSKVARA FELIILSRVL VGICAGIAYS 150
    TLPMYLGELA PQNLRGALGT MTEVFVIIGV LLAQIFSLQA ILGNATGWPI 200
    LLALTGVPAV IQLLSLPFFP ESPRYTLIEK GDEETARQAL RRLRGQNYNV 250
    EAEMEEMRTE ERTEQAEGRL SVLNLFTFRP LRWQLISIVV LMAGQQLSGI 300
    NAVNYYADVI YTSAGVDPTQ SQYVTLGSGV INLVMTLVSA VIIERLGRRI 350
    LLLSGYAICC SACLVLTVAL LLQSTAPELS YLSIVCVFSY IVGHSIGPSP 400
    VPSVVRTEIV LQSSRTAAFT VDGAVHWLTN FIVGLTFPSI QVAIGAYSFL 450
    VFAGVCILTA AYIYVVIPET KGRTFVEINC AFAKRNGVEF PEEKEVATAK 500
    PHTPSLPTKE TAF 513
    Length:513
    Mass (Da):55,886
    Last modified:February 5, 2008 - v1
    Checksum:iC4FFBFE9EE8061B9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606971 Genomic DNA. No translation available.
    UniGeneiMm.359648.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606971 Genomic DNA. No translation available.
    UniGenei Mm.359648.

    3D structure databases

    ProteinModelPortali P0C6A1.
    SMRi P0C6A1. Positions 78-111.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P0C6A1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:3650865. Slc2a7.

    Phylogenomic databases

    eggNOGi COG0477.
    HOVERGENi HBG014816.
    InParanoidi P0C6A1.

    Miscellaneous databases

    PROi P0C6A1.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori P0C6A1.

    Family and domain databases

    InterProi IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view ]
    Pfami PF00083. Sugar_tr. 1 hit.
    [Graphical view ]
    PRINTSi PR00171. SUGRTRNSPORT.
    SUPFAMi SSF103473. SSF103473. 1 hit.
    TIGRFAMsi TIGR00879. SP. 1 hit.
    PROSITEi PS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.

    Entry informationi

    Entry nameiGTR7_MOUSE
    AccessioniPrimary (citable) accession number: P0C6A1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3