Reviewed, UniProtKB/Swiss-Prot P0C5K6 (CT18_HUMAN)

Names and origin

Protein names

Recommended name:
    Putative tumor antigen NA88-A
Alternative name(s):
    Cancer/testis antigen 18
      Short name=CT18

Gene names

Name:

VENTXP1

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	33 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Uncertain.

General annotation (Comments)

Tissue specificity	Expressed in testis and melanoma cell lines. Ref.1
Caution	Could be the product of a pseudogene. This peptide sequence originates from a processed pseudogene derived from a retro-transcript of the mRNA coding for VENTX. The protein sequence is translated from a region that corresponds to the 3'-UTR of the original gene.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 33	33	Putative tumor antigen NA88-A		PRO_0000308923

Sequences

	Sequence		Length	Mass (Da)
	P0C5K6-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: F4A5BAA0743183DD	FASTA	33	3,500
	10 20 30 MSPPSSMCSP VPLLAAASGQ NRMTQGQHFL QKV

References

[1]

"A processed pseudogene codes for a new antigen recognized by a CD8(+) T cell clone on melanoma." Moreau-Aubry A., Le Guiner S., Labarriere N., Gesnel M.-C., Jotereau F., Breathnach R. J. Exp. Med. 191:1617-1624(2000) [PubMed: 10790436] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, IDENTIFICATION AS A CANCER/TESTIS ANTIGEN.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF164963 mRNA. No translation available.
IPI	IPI00868893.
UniGene	Hs.447377
3D structure databases
ModBase	Search...
Organism-specific databases
GeneCards	GC0XP026486.
HGNC	HGNC:30900. VENTXP1.
GenAtlas	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CT18_HUMAN

Accession

Primary (citable) accession number: P0C5K6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	October 23, 2007
Last modified:	March 3, 2009
This is version 5 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)