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Protein

B9 domain-containing protein 2

Gene

B9d2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cilium biogenesis/degradation

Enzyme and pathway databases

ReactomeiR-RNO-2467813. Separation of Sister Chromatids.
R-RNO-2500257. Resolution of Sister Chromatid Cohesion.
R-RNO-5620912. Anchoring of the basal body to the plasma membrane.
R-RNO-5663220. RHO GTPases Activate Formins.
R-RNO-68877. Mitotic Prometaphase.

Names & Taxonomyi

Protein namesi
Recommended name:
B9 domain-containing protein 2
Gene namesi
Name:B9d2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1566122. B9d2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003076761 – 175B9 domain-containing protein 2Add BLAST175

Proteomic databases

PaxDbiP0C5J3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000028753.

Interactioni

Subunit structurei

Part of the tectonic-like complex (also named B9 complex). Interacts with TUBG1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028029.

Structurei

3D structure databases

ProteinModelPortaliP0C5J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 118B9PROSITE-ProRule annotationAdd BLAST117

Sequence similaritiesi

Belongs to the B9D family.Curated
Contains 1 B9 domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4028. Eukaryota.
ENOG410ZQAW. LUCA.
GeneTreeiENSGT00530000063756.
HOGENOMiHOG000257718.
HOVERGENiHBG107102.
InParanoidiP0C5J3.
KOiK16745.
OMAiQVWHQDS.
OrthoDBiEOG091G0BGX.
PhylomeDBiP0C5J3.

Family and domain databases

InterProiIPR010796. B9_dom.
[Graphical view]
PfamiPF07162. B9-C2. 1 hit.
[Graphical view]
PROSITEiPS51381. B9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C5J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVHVIGQI IGATGFSEGS LFCKWGIHTG AAWKLLSGVR EGQTQVDTPQ
60 70 80 90 100
TGDMAYWSHP IDLHFATKGL QGWPRLHLQV WSQDSFGRCQ LAGYGFCHVP
110 120 130 140 150
SSPGTHQLDC PTWRPLGSWR EQLARAFVGG GPQLLHADTI YSGADRYRLH
160 170
TAAGGTVHLG IGLLLRHFDR YGVEC
Length:175
Mass (Da):19,208
Last modified:October 23, 2007 - v1
Checksum:i82AF5748A70DFE50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AI227900 mRNA. No translation available.
RefSeqiNP_001100964.1. NM_001107494.1.
XP_006228500.1. XM_006228438.3.
UniGeneiRn.22197.

Genome annotation databases

EnsembliENSRNOT00000028029; ENSRNOP00000028029; ENSRNOG00000028753.
GeneIDi308443.
KEGGirno:308443.
UCSCiRGD:1566122. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AI227900 mRNA. No translation available.
RefSeqiNP_001100964.1. NM_001107494.1.
XP_006228500.1. XM_006228438.3.
UniGeneiRn.22197.

3D structure databases

ProteinModelPortaliP0C5J3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028029.

Proteomic databases

PaxDbiP0C5J3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028029; ENSRNOP00000028029; ENSRNOG00000028753.
GeneIDi308443.
KEGGirno:308443.
UCSCiRGD:1566122. rat.

Organism-specific databases

CTDi80776.
RGDi1566122. B9d2.

Phylogenomic databases

eggNOGiKOG4028. Eukaryota.
ENOG410ZQAW. LUCA.
GeneTreeiENSGT00530000063756.
HOGENOMiHOG000257718.
HOVERGENiHBG107102.
InParanoidiP0C5J3.
KOiK16745.
OMAiQVWHQDS.
OrthoDBiEOG091G0BGX.
PhylomeDBiP0C5J3.

Enzyme and pathway databases

ReactomeiR-RNO-2467813. Separation of Sister Chromatids.
R-RNO-2500257. Resolution of Sister Chromatid Cohesion.
R-RNO-5620912. Anchoring of the basal body to the plasma membrane.
R-RNO-5663220. RHO GTPases Activate Formins.
R-RNO-68877. Mitotic Prometaphase.

Miscellaneous databases

PROiP0C5J3.

Gene expression databases

BgeeiENSRNOG00000028753.

Family and domain databases

InterProiIPR010796. B9_dom.
[Graphical view]
PfamiPF07162. B9-C2. 1 hit.
[Graphical view]
PROSITEiPS51381. B9. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB9D2_RAT
AccessioniPrimary (citable) accession number: P0C5J3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.