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Protein

B9 domain-containing protein 1

Gene

B9d1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCilium biogenesis/degradation

Enzyme and pathway databases

ReactomeiR-RNO-5620912 Anchoring of the basal body to the plasma membrane

Names & Taxonomyi

Protein namesi
Recommended name:
B9 domain-containing protein 1
Alternative name(s):
Endothelial precursor cells protein B9
Gene namesi
Name:B9d1
Synonyms:Eppb9
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1305522 B9d1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003076691 – 204B9 domain-containing protein 1Add BLAST204

Proteomic databases

PaxDbiP0C5J2

Expressioni

Gene expression databases

BgeeiENSRNOG00000002462
ExpressionAtlasiP0C5J2 baseline
GenevisibleiP0C5J2 RN

Interactioni

Subunit structurei

Part of the tectonic-like complex (also named B9 complex).By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000065889

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 127B9PROSITE-ProRule annotationAdd BLAST119

Sequence similaritiesi

Belongs to the B9D family.Curated

Phylogenomic databases

eggNOGiKOG4027 Eukaryota
ENOG410XP62 LUCA
GeneTreeiENSGT00530000063756
HOGENOMiHOG000038832
HOVERGENiHBG104431
InParanoidiP0C5J2
KOiK16744
OMAiGHFNEPI
OrthoDBiEOG091G0BGX
PhylomeDBiP0C5J2

Family and domain databases

InterProiView protein in InterPro
IPR010796 B9_dom
PANTHERiPTHR12968 PTHR12968, 1 hit
PfamiView protein in Pfam
PF07162 B9-C2, 1 hit
PROSITEiView protein in PROSITE
PS51381 B9, 1 hit

Sequencei

Sequence statusi: Complete.

P0C5J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAASPSVFL LMVNGQVESA QFPEYDDLYC KYCFVYGQDW APTAGLEEGI
60 70 80 90 100
SQIASKSQDV RQALVWNFPI DVTFKSTNPY GWPQIVLSVY GPDVFGNDVV
110 120 130 140 150
RGYGAVHVPF SPGRHKRTIP MFVPESTSTL QKFTSWFMGR RPEYTDPKVV
160 170 180 190 200
AQGEGREVTR VRSQGFVTLL FNVVTKDMKK LGYDTGPVDT QGVLSPSLPQ

GNPQ
Length:204
Mass (Da):22,655
Last modified:October 23, 2007 - v1
Checksum:i144D2EA35B002C58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AW915603 mRNA No translation available.
RefSeqiNP_001099256.1, NM_001105786.1
XP_017453132.1, XM_017597643.1
XP_017459566.1, XM_017604077.1
UniGeneiRn.3741

Genome annotation databases

EnsembliENSRNOT00000003402; ENSRNOP00000003402; ENSRNOG00000002462
ENSRNOT00000075073; ENSRNOP00000065889; ENSRNOG00000047790
GeneIDi108348055
287383
KEGGirno:108348055
rno:287383
UCSCiRGD:1305522 rat

Similar proteinsi

Entry informationi

Entry nameiB9D1_RAT
AccessioniPrimary (citable) accession number: P0C5J2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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