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P0C5J2

- B9D1_RAT

UniProt

P0C5J2 - B9D1_RAT

Protein

B9 domain-containing protein 1

Gene

B9d1

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling By similarity.By similarity

    GO - Molecular functioni

    1. hedgehog receptor activity Source: UniProtKB

    GO - Biological processi

    1. cilium assembly Source: UniProtKB
    2. cilium morphogenesis Source: UniProtKB
    3. smoothened signaling pathway Source: UniProtKB

    Keywords - Biological processi

    Cilium biogenesis/degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    B9 domain-containing protein 1
    Alternative name(s):
    Endothelial precursor cells protein B9
    Gene namesi
    Name:B9d1
    Synonyms:Eppb9
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 10

    Organism-specific databases

    RGDi1305522. B9d1.

    Subcellular locationi

    Cytoplasmcytoskeletoncilium basal body By similarity
    Note: Localizes at the transition zone, a region between the basal body and the ciliary axoneme.By similarity

    GO - Cellular componenti

    1. centrosome Source: UniProtKB
    2. ciliary basal body Source: UniProtKB
    3. ciliary transition zone Source: UniProtKB
    4. cytoplasm Source: UniProtKB-KW
    5. TCTN-B9D complex Source: UniProtKB

    Keywords - Cellular componenti

    Cell projection, Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 204204B9 domain-containing protein 1PRO_0000307669Add
    BLAST

    Proteomic databases

    PaxDbiP0C5J2.

    Expressioni

    Gene expression databases

    GenevestigatoriP0C5J2.

    Interactioni

    Subunit structurei

    Part of the tectonic-like complex (also named B9 complex).By similarity

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini9 – 127119B9PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the B9D family.Curated
    Contains 1 B9 domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG271150.
    GeneTreeiENSGT00530000063756.
    HOGENOMiHOG000038832.
    HOVERGENiHBG104431.
    InParanoidiP0C5J2.
    KOiK16744.
    OMAiWPQLVVS.
    OrthoDBiEOG78D7M7.
    PhylomeDBiP0C5J2.

    Family and domain databases

    InterProiIPR010796. B9_dom.
    [Graphical view]
    PfamiPF07162. B9-C2. 1 hit.
    [Graphical view]
    PROSITEiPS51381. B9. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0C5J2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAASPSVFL LMVNGQVESA QFPEYDDLYC KYCFVYGQDW APTAGLEEGI    50
    SQIASKSQDV RQALVWNFPI DVTFKSTNPY GWPQIVLSVY GPDVFGNDVV 100
    RGYGAVHVPF SPGRHKRTIP MFVPESTSTL QKFTSWFMGR RPEYTDPKVV 150
    AQGEGREVTR VRSQGFVTLL FNVVTKDMKK LGYDTGPVDT QGVLSPSLPQ 200
    GNPQ 204
    Length:204
    Mass (Da):22,655
    Last modified:October 23, 2007 - v1
    Checksum:i144D2EA35B002C58
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AW915603 mRNA. No translation available.
    RefSeqiNP_001099256.1. NM_001105786.1.
    XP_003750891.1. XM_003750843.2.
    UniGeneiRn.3741.

    Genome annotation databases

    EnsembliENSRNOT00000003402; ENSRNOP00000003402; ENSRNOG00000002462.
    ENSRNOT00000075073; ENSRNOP00000065889; ENSRNOG00000047790.
    GeneIDi100911746.
    287383.
    KEGGirno:100911746.
    rno:287383.
    UCSCiRGD:1305522. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AW915603 mRNA. No translation available.
    RefSeqi NP_001099256.1. NM_001105786.1.
    XP_003750891.1. XM_003750843.2.
    UniGenei Rn.3741.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi P0C5J2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000003402 ; ENSRNOP00000003402 ; ENSRNOG00000002462 .
    ENSRNOT00000075073 ; ENSRNOP00000065889 ; ENSRNOG00000047790 .
    GeneIDi 100911746.
    287383.
    KEGGi rno:100911746.
    rno:287383.
    UCSCi RGD:1305522. rat.

    Organism-specific databases

    CTDi 27077.
    RGDi 1305522. B9d1.

    Phylogenomic databases

    eggNOGi NOG271150.
    GeneTreei ENSGT00530000063756.
    HOGENOMi HOG000038832.
    HOVERGENi HBG104431.
    InParanoidi P0C5J2.
    KOi K16744.
    OMAi WPQLVVS.
    OrthoDBi EOG78D7M7.
    PhylomeDBi P0C5J2.

    Miscellaneous databases

    NextBioi 626001.
    PROi P0C5J2.

    Gene expression databases

    Genevestigatori P0C5J2.

    Family and domain databases

    InterProi IPR010796. B9_dom.
    [Graphical view ]
    Pfami PF07162. B9-C2. 1 hit.
    [Graphical view ]
    PROSITEi PS51381. B9. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Rat genome project: generation of a rat EST (REST) catalog & rat gene index."
      Lee N.H., Glodek A., Chandra I., Mason T.M., Quackenbush J., Kerlavage A.R., Adams M.D.
      Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.

    Entry informationi

    Entry nameiB9D1_RAT
    AccessioniPrimary (citable) accession number: P0C5J2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3