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P0C5D9

- RIFK_CHAGB

UniProt

P0C5D9 - RIFK_CHAGB

Protein

Riboflavin kinase

Gene

FMN1

Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

    Catalytic activityi

    ATP + riboflavin = ADP + FMN.

    Cofactori

    Zinc or magnesium.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi45 – 451Magnesium or zincBy similarity
    Active sitei140 – 1401NucleophileBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. riboflavin kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. FMN biosynthetic process Source: UniProtKB-UniPathway
    2. riboflavin biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

    Enzyme and pathway databases

    UniPathwayiUPA00276; UER00406.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Riboflavin kinase (EC:2.7.1.26)
    Alternative name(s):
    Flavin mononucleotide kinase 1
    Gene namesi
    Name:FMN1
    ORF Names:CHGG_09149.2
    OrganismiChaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
    Taxonomic identifieri306901 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeChaetomium
    ProteomesiUP000001056: Unassembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 235235Riboflavin kinasePRO_0000301839Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP0C5D9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi86 – 9813Poly-AlaAdd
    BLAST

    Sequence similaritiesi

    Belongs to the flavokinase family.Curated

    Phylogenomic databases

    OrthoDBiEOG7K3V05.

    Family and domain databases

    Gene3Di2.40.30.30. 2 hits.
    InterProiIPR023468. Riboflavin_kinase.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    [Graphical view]
    PANTHERiPTHR22749. PTHR22749. 1 hit.
    PfamiPF01687. Flavokinase. 1 hit.
    [Graphical view]
    SMARTiSM00904. Flavokinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF82114. SSF82114. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    P0C5D9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHQPPNRPP LIGDPSGPAP PYPFRMSGLV ISGFGRGSKE LGIPTANLPV    50
    DDAQTPWISS IPSGVYFGWA SLNLPASHPD SLTSSAAAAA AAAAAAAAPG 100
    EDGGGAGEQR QRGGNGFAVY PMVMSIGYNP FYKNTVRSAE VHVLHRFGAD 150
    FYGVEMRLLI AGFIREEKDY SGLEALIADI EFDCEVAKRS LAREGWAPSG 200
    VDVEVDVPGE GVKVLRGSLE CGWLIRPDEL GEGGK 235
    Length:235
    Mass (Da):24,680
    Last modified:September 11, 2007 - v1
    Checksum:i90586511CDB868EF
    GO

    Sequence cautioni

    The sequence EAQ85135.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene CHGG_09149 has been split into 2 genes: CHGG_09149.1 and CHGG_09149.2.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408034 Genomic DNA. Translation: EAQ85135.1. Sequence problems.
    RefSeqiXP_001227076.1. XM_001227075.1.

    Genome annotation databases

    GeneIDi4395860.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408034 Genomic DNA. Translation: EAQ85135.1 . Sequence problems.
    RefSeqi XP_001227076.1. XM_001227075.1.

    3D structure databases

    ProteinModelPortali P0C5D9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4395860.

    Phylogenomic databases

    OrthoDBi EOG7K3V05.

    Enzyme and pathway databases

    UniPathwayi UPA00276 ; UER00406 .

    Family and domain databases

    Gene3Di 2.40.30.30. 2 hits.
    InterProi IPR023468. Riboflavin_kinase.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    [Graphical view ]
    PANTHERi PTHR22749. PTHR22749. 1 hit.
    Pfami PF01687. Flavokinase. 1 hit.
    [Graphical view ]
    SMARTi SM00904. Flavokinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF82114. SSF82114. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970.

    Entry informationi

    Entry nameiRIFK_CHAGB
    AccessioniPrimary (citable) accession number: P0C5D9
    Secondary accession number(s): Q2GSA5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3