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P0C5D9

- RIFK_CHAGB

UniProt

P0C5D9 - RIFK_CHAGB

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Protein

Riboflavin kinase

Gene

FMN1

Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zinc or magnesium.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi45 – 451Magnesium or zincBy similarity
Active sitei140 – 1401NucleophileBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:FMN1
ORF Names:CHGG_09149.2
OrganismiChaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
Taxonomic identifieri306901 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeChaetomium
ProteomesiUP000001056: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Riboflavin kinasePRO_0000301839Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP0C5D9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi86 – 9813Poly-AlaAdd
BLAST

Sequence similaritiesi

Belongs to the flavokinase family.Curated

Phylogenomic databases

InParanoidiP0C5D9.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 2 hits.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 2 hits.

Sequencei

Sequence statusi: Complete.

P0C5D9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAHQPPNRPP LIGDPSGPAP PYPFRMSGLV ISGFGRGSKE LGIPTANLPV
60 70 80 90 100
DDAQTPWISS IPSGVYFGWA SLNLPASHPD SLTSSAAAAA AAAAAAAAPG
110 120 130 140 150
EDGGGAGEQR QRGGNGFAVY PMVMSIGYNP FYKNTVRSAE VHVLHRFGAD
160 170 180 190 200
FYGVEMRLLI AGFIREEKDY SGLEALIADI EFDCEVAKRS LAREGWAPSG
210 220 230
VDVEVDVPGE GVKVLRGSLE CGWLIRPDEL GEGGK
Length:235
Mass (Da):24,680
Last modified:September 11, 2007 - v1
Checksum:i90586511CDB868EF
GO

Sequence cautioni

The sequence EAQ85135.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene CHGG_09149 has been split into 2 genes: CHGG_09149.1 and CHGG_09149.2.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408034 Genomic DNA. Translation: EAQ85135.1. Sequence problems.
RefSeqiXP_001227076.1. XM_001227075.1.

Genome annotation databases

GeneIDi4395860.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408034 Genomic DNA. Translation: EAQ85135.1 . Sequence problems.
RefSeqi XP_001227076.1. XM_001227075.1.

3D structure databases

ProteinModelPortali P0C5D9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4395860.

Phylogenomic databases

InParanoidi P0C5D9.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 2 hits.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970.

Entry informationi

Entry nameiRIFK_CHAGB
AccessioniPrimary (citable) accession number: P0C5D9
Secondary accession number(s): Q2GSA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3