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P0C5D9 (RIFK_CHAGB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin kinase

EC=2.7.1.26
Alternative name(s):
Flavin mononucleotide kinase 1
Gene names
Name:FMN1
ORF Names:CHGG_09149.2
OrganismChaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus) [Complete proteome]
Taxonomic identifier306901 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeChaetomium

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activity

ATP + riboflavin = ADP + FMN.

Cofactor

Zinc or magnesium By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the flavokinase family.

Sequence caution

The sequence EAQ85135.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene CHGG_09149 has been split into 2 genes: CHGG_09149.1 and CHGG_09149.2.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 235235Riboflavin kinase
PRO_0000301839

Regions

Compositional bias86 – 9813Poly-Ala

Sites

Active site1401Nucleophile By similarity
Metal binding451Magnesium or zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C5D9 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 90586511CDB868EF

FASTA23524,680
        10         20         30         40         50         60 
MAHQPPNRPP LIGDPSGPAP PYPFRMSGLV ISGFGRGSKE LGIPTANLPV DDAQTPWISS 

        70         80         90        100        110        120 
IPSGVYFGWA SLNLPASHPD SLTSSAAAAA AAAAAAAAPG EDGGGAGEQR QRGGNGFAVY 

       130        140        150        160        170        180 
PMVMSIGYNP FYKNTVRSAE VHVLHRFGAD FYGVEMRLLI AGFIREEKDY SGLEALIADI 

       190        200        210        220        230 
EFDCEVAKRS LAREGWAPSG VDVEVDVPGE GVKVLRGSLE CGWLIRPDEL GEGGK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH408034 Genomic DNA. Translation: EAQ85135.1. Sequence problems.
RefSeqXP_001227076.1. XM_001227075.1.

3D structure databases

ProteinModelPortalP0C5D9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4395860.

Phylogenomic databases

OrthoDBEOG7K3V05.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.

Family and domain databases

Gene3D2.40.30.30. 2 hits.
InterProIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 2 hits.
ProtoNetSearch...

Entry information

Entry nameRIFK_CHAGB
AccessionPrimary (citable) accession number: P0C5D9
Secondary accession number(s): Q2GSA5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: January 22, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways