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P0C5D7

- PP2A4_ORYSI

UniProt

P0C5D7 - PP2A4_ORYSI

Protein

Putative serine/threonine-protein phosphatase PP2A-4 catalytic subunit

Gene

PP2A4

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (11 Sep 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi63 – 631Manganese 1By similarity
    Metal bindingi65 – 651Manganese 1By similarity
    Metal bindingi91 – 911Manganese 1By similarity
    Metal bindingi91 – 911Manganese 2By similarity
    Metal bindingi123 – 1231Manganese 2By similarity
    Active sitei124 – 1241Proton donorBy similarity
    Metal bindingi173 – 1731Manganese 2By similarity
    Metal bindingi247 – 2471Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative serine/threonine-protein phosphatase PP2A-4 catalytic subunit (EC:3.1.3.16)
    Gene namesi
    Name:PP2A4
    OrganismiOryza sativa subsp. indica (Rice)
    Taxonomic identifieri39946 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

    Organism-specific databases

    GrameneiP0C5D7.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 315315Putative serine/threonine-protein phosphatase PP2A-4 catalytic subunitPRO_0000301658Add
    BLAST

    Proteomic databases

    PRIDEiP0C5D7.

    Structurei

    3D structure databases

    ProteinModelPortaliP0C5D7.
    SMRiP0C5D7. Positions 16-315.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-2A subfamily.Curated

    Phylogenomic databases

    HOGENOMiHOG000172696.

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0C5D7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEESVGSRGG SGGGGLDAQI EQLMECRPLS ETEVKTLCEK AKEILMEESN    50
    VQPVKSPVTI CGDIHGQFHD LVELFRIGGK CPDTNYLFMG DYVDRGYYSV 100
    ETVTLLVALK VRYPQRITIL RGNHESRQIT QVYGFYDECL RKYGSANVWK 150
    IFTDLFDYFP LTALVESEIF CLHGGLSPSI DNLDSVRSLD RVQEVPHEGP 200
    MCDLLWSDPD DRCGWGISPR GAGYTFGQDI SEQFNHSNNL KLVARAHQLV 250
    MEGYNWAHEQ KVVTIFSAPN YCYRCGNMAS ILEVDDCRNH TFIQFEPAPR 300
    RGEPDVTRRT PDYFL 315
    Length:315
    Mass (Da):35,702
    Last modified:September 11, 2007 - v1
    Checksum:i16C878B644231454
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF173881 Genomic DNA. Translation: AAD48068.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF173881 Genomic DNA. Translation: AAD48068.1 .

    3D structure databases

    ProteinModelPortali P0C5D7.
    SMRi P0C5D7. Positions 16-315.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P0C5D7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei P0C5D7.

    Phylogenomic databases

    HOGENOMi HOG000172696.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning and characterization of protein phosphatase 2A catalytic subunit genes from Oryza sativa."
      Yu R.M.K., Kong R.Y.C.
      Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. IR36.

    Entry informationi

    Entry nameiPP2A4_ORYSI
    AccessioniPrimary (citable) accession number: P0C5D7
    Secondary accession number(s): Q0IXS3, Q338E3, Q9SBW3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3