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P0C5D7 (PP2A4_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein phosphatase PP2A-4 catalytic subunit
EC=3.1.3.16
Gene names
Name:PP2A4
OrganismOryza sativa subsp. indica (Rice)
Taxonomic identifier39946 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-2A subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandIron
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 315315Putative serine/threonine-protein phosphatase PP2A-4 catalytic subunit
PRO_0000301658

Sites

Active site1241Proton donor By similarity
Metal binding631Iron By similarity
Metal binding651Iron By similarity
Metal binding911Iron By similarity
Metal binding911Manganese By similarity
Metal binding1231Manganese By similarity
Metal binding1731Manganese By similarity
Metal binding2471Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C5D7 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 16C878B644231454

FASTA31535,702
        10         20         30         40         50         60 
MEESVGSRGG SGGGGLDAQI EQLMECRPLS ETEVKTLCEK AKEILMEESN VQPVKSPVTI 

        70         80         90        100        110        120 
CGDIHGQFHD LVELFRIGGK CPDTNYLFMG DYVDRGYYSV ETVTLLVALK VRYPQRITIL 

       130        140        150        160        170        180 
RGNHESRQIT QVYGFYDECL RKYGSANVWK IFTDLFDYFP LTALVESEIF CLHGGLSPSI 

       190        200        210        220        230        240 
DNLDSVRSLD RVQEVPHEGP MCDLLWSDPD DRCGWGISPR GAGYTFGQDI SEQFNHSNNL 

       250        260        270        280        290        300 
KLVARAHQLV MEGYNWAHEQ KVVTIFSAPN YCYRCGNMAS ILEVDDCRNH TFIQFEPAPR 

       310 
RGEPDVTRRT PDYFL

« Hide

References

[1]"Molecular cloning and characterization of protein phosphatase 2A catalytic subunit genes from Oryza sativa."
Yu R.M.K., Kong R.Y.C.
Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. IR36.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF173881 Genomic DNA. Translation: AAD48068.1.

3D structure databases

ProteinModelPortalP0C5D7.
SMRP0C5D7. Positions 16-315.
ModBaseSearch...

Proteomic databases

PRIDEP0C5D7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP0C5D7.

Phylogenomic databases

HOGENOMHOG000172696.

Gene expression databases

ArrayExpressP0C5D7.

Family and domain databases

InterProIPR004843. Metallo_PEstase_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP2A4_ORYSI
AccessionPrimary (citable) accession number: P0C5D7
Secondary accession number(s): Q0IXS3, Q338E3, Q9SBW3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: April 3, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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