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P0C5A0 (DUPD1_GASAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

protein tyrosine/serine/threonine phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Dual specificity phosphatase DUPD1
PRO_0000295887

Regions

Domain47 – 193147Tyrosine-protein phosphatase
Region138 – 1458Substrate binding By similarity

Sites

Active site1391Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C5A0 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 2E2ADDE90A74AA4C

FASTA20623,359
        10         20         30         40         50         60 
MSSRVVKSRS KNPYAAVQVD PDSDYITPGT LDLEQLFWTS TGAQYAHVNQ VWPSVYVGDE 

        70         80         90        100        110        120 
KTALERPGLR VLGITHVLNA AEGKWNNVLT GAHYYTDMDI QYFGVEADDK PTFNISQFFC 

       130        140        150        160        170        180 
SATQFIHEAL SHPKVLVHCV MGRSRSAALV LAYLMMEHGL TVVDAIEHVR QRRCVLPNHG 

       190        200 
FLRQLRALDI TLQEDRLRQK RGMQEQ 

« Hide

References

[1]Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AANH01005129 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalP0C5A0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING69293.ENSGACP00000008697.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG2453.
HOVERGENHBG001524.

Family and domain databases

InterProIPR020417. Atypical_DUSP.
IPR020405. Atypical_DUSP_famA.
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PRINTSPR01908. ADSPHPHTASE.
PR01909. ADSPHPHTASEA.
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDUPD1_GASAC
AccessionPrimary (citable) accession number: P0C5A0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families