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P0C598 (DUPD1_ANOCA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dual specificity phosphatase DUPD1

EC=3.1.3.16
EC=3.1.3.48
Gene names
Name:DUPD1
OrganismAnolis carolinensis (Green anole) (American chameleon) [Reference proteome]
Taxonomic identifier28377 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaIguanidaePolychrotinaeAnolis

Protein attributes

Sequence length217 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

protein tyrosine/serine/threonine phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 217217Dual specificity phosphatase DUPD1
PRO_0000295884

Regions

Domain46 – 193148Tyrosine-protein phosphatase
Region138 – 1458Substrate binding By similarity

Sites

Active site1391Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C598 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: F5A23775C2FDC3AA

FASTA21724,410
        10         20         30         40         50         60 
MSSTALKSGK ISAYAAVKVD PDGDYCTPGA FDLERLFWKG SPKYTHVNEV WPNLYIGDEK 

        70         80         90        100        110        120 
TALDRYSLEK AGFTHILNAA HGRWNVDTGP EYYSDMNIEY HGVEADDLPT FNLSPFFYSA 

       130        140        150        160        170        180 
AEFIHTALQN ETSKILVHCA MGRSRSAALV LAYLMIYKNM TVVDAIDQVL QHRCILPNRG 

       190        200        210 
FLKQLRELDI KLALERRDNM NGTNSSEKTG TSTETEI 

« Hide

References

[1]"The genome sequence of Anolis carolinensis (green anole)."
DiPalma F., Grabherr M., Lander E.S., Lindblad-Toh K.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAWZ01006385 Genomic DNA. No translation available.
AAWZ01006387 Genomic DNA. No translation available.
UniGeneAcr.11361.

3D structure databases

ProteinModelPortalP0C598.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28377.ENSACAP00000008506.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG2453.
HOGENOMHOG000233767.
HOVERGENHBG001524.

Family and domain databases

InterProIPR020417. Atypical_DUSP.
IPR020405. Atypical_DUSP_famA.
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PRINTSPR01908. ADSPHPHTASE.
PR01909. ADSPHPHTASEA.
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDUPD1_ANOCA
AccessionPrimary (citable) accession number: P0C598
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families