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P0C597 (DUPD1_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dual specificity phosphatase DUPD1

EC=3.1.3.16
EC=3.1.3.48
Gene names
Name:DUPD1
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein dephosphorylation

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

protein tyrosine/serine/threonine phosphatase activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Dual specificity phosphatase DUPD1
PRO_0000295883

Regions

Domain46 – 193148Tyrosine-protein phosphatase
Region138 – 1458Substrate binding By similarity

Sites

Active site1391Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P0C597 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 7ED254A3C511B503

FASTA21424,322
        10         20         30         40         50         60 
MSSAGLNVGK KNAYTAVKVD PDGDYCTPGA FELERLFWKG CPKYTHVNEV WPNLYIGDEK 

        70         80         90        100        110        120 
TALDRYSLEK AGFTHILNAA HGQRNVDTGP EYYQDMTVEY HGVEADDLPT FKLSQFFYSA 

       130        140        150        160        170        180 
SEFIDNALQD ERNKVLVHCA MGRSRSATLV LAYLMIYKNM TVVDAIEQVS RHRCILPNRG 

       190        200        210 
FLKQLRELDI ELALQRRNTK NSLPSNDDEN STTI 

« Hide

References

[1]"ESTs from brain and testis of White Leghorn and red junglefowl: annotation, bioinformatic classification of unknown transcripts and analysis of expression levels."
Savolainen P., Fitzsimmons C., Arvestad L., Andersson L., Lundeberg J.
Cytogenet. Genome Res. 111:79-87(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: White leghorn.
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CN231188 mRNA. No translation available.
UniGeneGga.11383.

3D structure databases

ProteinModelPortalP0C597.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000008022.

Proteomic databases

PaxDbP0C597.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG2453.
HOGENOMHOG000233767.
HOVERGENHBG001524.
OMAERIWRTH.
OrthoDBEOG7CZK7N.
PhylomeDBP0C597.
TreeFamTF105128.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR020417. Atypical_DUSP.
IPR020405. Atypical_DUSP_famA.
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PRINTSPR01908. ADSPHPHTASE.
PR01909. ADSPHPHTASEA.
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 1 hit.
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP0C597.

Entry information

Entry nameDUPD1_CHICK
AccessionPrimary (citable) accession number: P0C597
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families