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Protein

Putative mitochondrial 2-oxoglutarate/malate carrier protein

Gene

mic-33

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative mitochondrial 2-oxoglutarate/malate carrier protein
Short name:
OGCP
Alternative name(s):
Mitochondrial carrier 33
Gene namesi
Name:mic-33
ORF Names:NCU04792, NCU10732
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 5, Linkage Group VI

Organism-specific databases

EuPathDBiFungiDB:NCU10732.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 62Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei103 – 121Helical; Name=2Sequence analysisAdd BLAST19
Transmembranei148 – 168Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei199 – 219Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei245 – 265Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei309 – 329Helical; Name=6Sequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002953331 – 331Putative mitochondrial 2-oxoglutarate/malate carrier proteinAdd BLAST331

Structurei

3D structure databases

ProteinModelPortaliP0C582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati39 – 128Solcar 1Add BLAST90
Repeati140 – 231Solcar 2Add BLAST92
Repeati239 – 329Solcar 3Add BLAST91

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000165139.
KOiK15104.
OMAiGFTPYYF.
OrthoDBiEOG092C42AD.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

P0C582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVKQSAQA ATSDVVDTAK NATAETVTAA TDFLHTPAVR AALPFINGGL
60 70 80 90 100
SGMVATTVIQ PIDMIKVRIQ LAGEGKAGGP KPTPLGVTRD IIASGKAMDL
110 120 130 140 150
YTGLSAGLLR QAVYTTARIG CFDTFMSRLS ARAKEKGQSV GFKERASAGL
160 170 180 190 200
AAGGLAAMIG NPADLALIRM QSDGLKPVAE RKNYKSVIDA LGGIARNEGV
210 220 230 240 250
AALWAGAAPT VVRAMALNFG QLAFFSEAKA QLKARTQWSS KVQTLSASAI
260 270 280 290 300
AGFFASFFSL PFDFVKTRLQ KQTRGPDGKL PYNGMVDCFA KVAKQEGVFR
310 320 330
FYRGFGTYYV RIAPHAMVTL LVADYLGWLT K
Length:331
Mass (Da):35,047
Last modified:July 24, 2007 - v1
Checksum:i93F8659380392C45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002241 Genomic DNA. Translation: ESA42143.1.
CM002241 Genomic DNA. Translation: ESA42144.1.
RefSeqiXP_011395026.1. XM_011396724.1.
XP_011395027.1. XM_011396725.1.

Genome annotation databases

EnsemblFungiiESA42143; ESA42143; NCU10732.
ESA42144; ESA42144; NCU10732.
GeneIDi5847541.
KEGGincr:NCU10732.

Similar proteinsi

Entry informationi

Entry nameiM2OM_NEUCR
AccessioniPrimary (citable) accession number: P0C582
Secondary accession number(s): A7UWG7, Q7S6P3, V5IKM2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: June 7, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families