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P0C525

- VIRB4_BRUAB

UniProt

P0C525 - VIRB4_BRUAB

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Protein

Type IV secretion system protein virB4

Gene

virB4

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi457 – 4648ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO262698:GJC2-2275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV secretion system protein virB4
Gene namesi
Name:virB4
Ordered Locus Names:BruAb2_0066
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 831831Type IV secretion system protein virB4PRO_0000290169Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi262698.BruAb2_0066.

Structurei

3D structure databases

ProteinModelPortaliP0C525.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrbE/VirB4 family.Curated

Phylogenomic databases

eggNOGiCOG3451.
HOGENOMiHOG000119263.
KOiK03199.
OMAiRYFRIRT.
OrthoDBiEOG6HMX9P.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR004346. CagE_TrbE_VirB.
IPR018145. CagE_TrbE_VirB_cntrl_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03135. CagE_TrbE_VirB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00929. VirB4_CagE. 1 hit.

Sequencei

Sequence statusi: Complete.

P0C525-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MGAQSKYAQQ LNNERSLAPF IPFRSQVGPT TVITRDGDFV RTWRIAGLAF
60 70 80 90 100
ETQDKEKLLI RKDQLNTLFR AIASNNVALW SHNVRRRTWD HLKSFFSNPF
110 120 130 140 150
CDALDKKYYG SFSGYRMMSN ELYLTVIYRP VPAKISRLFN VAVHRSHAEI
160 170 180 190 200
LQEQQLAIRK LDEIGNQIET SLRRYGGDDG RGIEVLSTYE DKHGALCSQQ
210 220 230 240 250
LEFYNFLLSG EWQKVRVPSC PLDEYLGTGW VYAGTETIEI RTANATRYAR
260 270 280 290 300
GIDFKDYANH TEPGILNGLM YSDYEYVITQ SFSFMTKRDG KEFLTRQKQR
310 320 330 340 350
LQNTEDGSAS QIMEMDIAID QLGRGDFVMG EYHYSLLVFA EDMETVRHNT
360 370 380 390 400
SHAMNILQDN GFLATVIATA TDAAFYAQLP CNWRYRPRVA GLTSLNFAGL
410 420 430 440 450
SCFHNFRAGK RDGNPWGQAL TLLKTPSGQP AYLNFHYSKG DEDNFDKKLL
460 470 480 490 500
GNTRIIGQSG AGKTVLMNFC LAQAQKYLHN APMGMCNVFF DKDQGAKGTI
510 520 530 540 550
LAIGGKYLAI RNGEPTGFNP FQMEPTAGNI LFLEKLVQVL VSRDGQHVTT
560 570 580 590 600
TDESRISHAI RTVMRMRPEL RRLSTVLQNV TEGSDRQDRE NSVAKRLAKW
610 620 630 640 650
CFDDGTGKRG TFWWVLDCPQ DQIDFNTHSN YGFDGTDFLD NADVRTPISM
660 670 680 690 700
YLLHRMELAI DGRRFIYWMD EAWKWVDDEA FSEFANNKQL TIRKQNGLGV
710 720 730 740 750
FATQMPSSLL NSKVASALVQ QVATEIYLPN PKADYHEYTD GFKVTNEEFD
760 770 780 790 800
IIRSMSEESR MFLVKQGHHS MICRLELNGF DDELAILSGS SDNNELLDQV
810 820 830
IAEVGDDPSV WLPVFQERRK ARIASSKSTG R
Length:831
Mass (Da):94,572
Last modified:June 12, 2007 - v1
Checksum:i657AAA319B4CC8E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75517.1.
RefSeqiYP_222878.1. NC_006933.1.

Genome annotation databases

EnsemblBacteriaiAAX75517; AAX75517; BruAb2_0066.
GeneIDi3341950.
KEGGibmb:BruAb2_0066.
PATRICi17826323. VBIBruAbo15061_2347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75517.1 .
RefSeqi YP_222878.1. NC_006933.1.

3D structure databases

ProteinModelPortali P0C525.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb2_0066.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX75517 ; AAX75517 ; BruAb2_0066 .
GeneIDi 3341950.
KEGGi bmb:BruAb2_0066.
PATRICi 17826323. VBIBruAbo15061_2347.

Phylogenomic databases

eggNOGi COG3451.
HOGENOMi HOG000119263.
KOi K03199.
OMAi RYFRIRT.
OrthoDBi EOG6HMX9P.

Enzyme and pathway databases

BioCyci BABO262698:GJC2-2275-MONOMER.

Miscellaneous databases

PROi P0C525.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR004346. CagE_TrbE_VirB.
IPR018145. CagE_TrbE_VirB_cntrl_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF03135. CagE_TrbE_VirB. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00929. VirB4_CagE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiVIRB4_BRUAB
AccessioniPrimary (citable) accession number: P0C525
Secondary accession number(s): Q57A17, Q9KIS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 12, 2007
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3