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P0C525 (VIRB4_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type IV secretion system protein virB4
Gene names
Name:virB4
Ordered Locus Names:BruAb2_0066
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length831 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the TrbE/VirB4 family.

Ontologies

Keywords
   Biological processVirulence
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 831831Type IV secretion system protein virB4
PRO_0000290169

Regions

Nucleotide binding457 – 4648ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P0C525 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 657AAA319B4CC8E5

FASTA83194,572
        10         20         30         40         50         60 
MGAQSKYAQQ LNNERSLAPF IPFRSQVGPT TVITRDGDFV RTWRIAGLAF ETQDKEKLLI 

        70         80         90        100        110        120 
RKDQLNTLFR AIASNNVALW SHNVRRRTWD HLKSFFSNPF CDALDKKYYG SFSGYRMMSN 

       130        140        150        160        170        180 
ELYLTVIYRP VPAKISRLFN VAVHRSHAEI LQEQQLAIRK LDEIGNQIET SLRRYGGDDG 

       190        200        210        220        230        240 
RGIEVLSTYE DKHGALCSQQ LEFYNFLLSG EWQKVRVPSC PLDEYLGTGW VYAGTETIEI 

       250        260        270        280        290        300 
RTANATRYAR GIDFKDYANH TEPGILNGLM YSDYEYVITQ SFSFMTKRDG KEFLTRQKQR 

       310        320        330        340        350        360 
LQNTEDGSAS QIMEMDIAID QLGRGDFVMG EYHYSLLVFA EDMETVRHNT SHAMNILQDN 

       370        380        390        400        410        420 
GFLATVIATA TDAAFYAQLP CNWRYRPRVA GLTSLNFAGL SCFHNFRAGK RDGNPWGQAL 

       430        440        450        460        470        480 
TLLKTPSGQP AYLNFHYSKG DEDNFDKKLL GNTRIIGQSG AGKTVLMNFC LAQAQKYLHN 

       490        500        510        520        530        540 
APMGMCNVFF DKDQGAKGTI LAIGGKYLAI RNGEPTGFNP FQMEPTAGNI LFLEKLVQVL 

       550        560        570        580        590        600 
VSRDGQHVTT TDESRISHAI RTVMRMRPEL RRLSTVLQNV TEGSDRQDRE NSVAKRLAKW 

       610        620        630        640        650        660 
CFDDGTGKRG TFWWVLDCPQ DQIDFNTHSN YGFDGTDFLD NADVRTPISM YLLHRMELAI 

       670        680        690        700        710        720 
DGRRFIYWMD EAWKWVDDEA FSEFANNKQL TIRKQNGLGV FATQMPSSLL NSKVASALVQ 

       730        740        750        760        770        780 
QVATEIYLPN PKADYHEYTD GFKVTNEEFD IIRSMSEESR MFLVKQGHHS MICRLELNGF 

       790        800        810        820        830 
DDELAILSGS SDNNELLDQV IAEVGDDPSV WLPVFQERRK ARIASSKSTG R 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017224 Genomic DNA. Translation: AAX75517.1.
RefSeqYP_222878.1. NC_006933.1.

3D structure databases

ProteinModelPortalP0C525.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb2_0066.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX75517; AAX75517; BruAb2_0066.
GeneID3341950.
KEGGbmb:BruAb2_0066.
PATRIC17826323. VBIBruAbo15061_2347.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3451.
HOGENOMHOG000119263.
KOK03199.
OMAFKDYASH.
OrthoDBEOG6HMX9P.
ProtClustDBCLSK884268.

Enzyme and pathway databases

BioCycBABO262698:GJC2-2275-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
InterProIPR004346. CagE_TrbE_VirB.
IPR018145. CagE_TrbE_VirB_cntrl_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF03135. CagE_TrbE_VirB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00929. VirB4_CagE. 1 hit.
ProtoNetSearch...

Other

PROP0C525.

Entry information

Entry nameVIRB4_BRUAB
AccessionPrimary (citable) accession number: P0C525
Secondary accession number(s): Q57A17, Q9KIS9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names