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P0C525

- VIRB4_BRUAB

UniProt

P0C525 - VIRB4_BRUAB

Protein

Type IV secretion system protein virB4

Gene

virB4

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi457 – 4648ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Virulence

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-2275-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type IV secretion system protein virB4
    Gene namesi
    Name:virB4
    Ordered Locus Names:BruAb2_0066
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome II

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 831831Type IV secretion system protein virB4PRO_0000290169Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi262698.BruAb2_0066.

    Structurei

    3D structure databases

    ProteinModelPortaliP0C525.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrbE/VirB4 family.Curated

    Phylogenomic databases

    eggNOGiCOG3451.
    HOGENOMiHOG000119263.
    KOiK03199.
    OMAiRYFRIRT.
    OrthoDBiEOG6HMX9P.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR004346. CagE_TrbE_VirB.
    IPR018145. CagE_TrbE_VirB_cntrl_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF03135. CagE_TrbE_VirB. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00929. VirB4_CagE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0C525-1 [UniParc]FASTAAdd to Basket

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    MGAQSKYAQQ LNNERSLAPF IPFRSQVGPT TVITRDGDFV RTWRIAGLAF    50
    ETQDKEKLLI RKDQLNTLFR AIASNNVALW SHNVRRRTWD HLKSFFSNPF 100
    CDALDKKYYG SFSGYRMMSN ELYLTVIYRP VPAKISRLFN VAVHRSHAEI 150
    LQEQQLAIRK LDEIGNQIET SLRRYGGDDG RGIEVLSTYE DKHGALCSQQ 200
    LEFYNFLLSG EWQKVRVPSC PLDEYLGTGW VYAGTETIEI RTANATRYAR 250
    GIDFKDYANH TEPGILNGLM YSDYEYVITQ SFSFMTKRDG KEFLTRQKQR 300
    LQNTEDGSAS QIMEMDIAID QLGRGDFVMG EYHYSLLVFA EDMETVRHNT 350
    SHAMNILQDN GFLATVIATA TDAAFYAQLP CNWRYRPRVA GLTSLNFAGL 400
    SCFHNFRAGK RDGNPWGQAL TLLKTPSGQP AYLNFHYSKG DEDNFDKKLL 450
    GNTRIIGQSG AGKTVLMNFC LAQAQKYLHN APMGMCNVFF DKDQGAKGTI 500
    LAIGGKYLAI RNGEPTGFNP FQMEPTAGNI LFLEKLVQVL VSRDGQHVTT 550
    TDESRISHAI RTVMRMRPEL RRLSTVLQNV TEGSDRQDRE NSVAKRLAKW 600
    CFDDGTGKRG TFWWVLDCPQ DQIDFNTHSN YGFDGTDFLD NADVRTPISM 650
    YLLHRMELAI DGRRFIYWMD EAWKWVDDEA FSEFANNKQL TIRKQNGLGV 700
    FATQMPSSLL NSKVASALVQ QVATEIYLPN PKADYHEYTD GFKVTNEEFD 750
    IIRSMSEESR MFLVKQGHHS MICRLELNGF DDELAILSGS SDNNELLDQV 800
    IAEVGDDPSV WLPVFQERRK ARIASSKSTG R 831
    Length:831
    Mass (Da):94,572
    Last modified:June 12, 2007 - v1
    Checksum:i657AAA319B4CC8E5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017224 Genomic DNA. Translation: AAX75517.1.
    RefSeqiYP_222878.1. NC_006933.1.

    Genome annotation databases

    EnsemblBacteriaiAAX75517; AAX75517; BruAb2_0066.
    GeneIDi3341950.
    KEGGibmb:BruAb2_0066.
    PATRICi17826323. VBIBruAbo15061_2347.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017224 Genomic DNA. Translation: AAX75517.1 .
    RefSeqi YP_222878.1. NC_006933.1.

    3D structure databases

    ProteinModelPortali P0C525.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb2_0066.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX75517 ; AAX75517 ; BruAb2_0066 .
    GeneIDi 3341950.
    KEGGi bmb:BruAb2_0066.
    PATRICi 17826323. VBIBruAbo15061_2347.

    Phylogenomic databases

    eggNOGi COG3451.
    HOGENOMi HOG000119263.
    KOi K03199.
    OMAi RYFRIRT.
    OrthoDBi EOG6HMX9P.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-2275-MONOMER.

    Miscellaneous databases

    PROi P0C525.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR004346. CagE_TrbE_VirB.
    IPR018145. CagE_TrbE_VirB_cntrl_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF03135. CagE_TrbE_VirB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00929. VirB4_CagE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiVIRB4_BRUAB
    AccessioniPrimary (citable) accession number: P0C525
    Secondary accession number(s): Q57A17, Q9KIS9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 12, 2007
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3