P0C2W7 (CT47B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cancer/testis antigen 47B

Alternative name(s):
Cancer/testis antigen 47.13
Short name=CT47.13

Gene names

Name:	CT47B1
Synonyms:	CT47.13

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 299	299	Cancer/testis antigen 47B		PRO_0000286433
Regions
	Coiled coil	270 – 298	29	Potential
	Compositional bias	92 – 99	8	Poly-Glu
	Compositional bias	168 – 171	4	Poly-Leu

Sequences

	Sequence		Length	Mass (Da)
	P0C2W7 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: E2FD8473EE062757	FASTA	299	31,319
	10 20 30 40 50 60 MSATGDRHPT QGDQEAPVSQ EGAQAEAAGA GNQEGGDSGP DSSDMVPAAE VVGVAGPVEG 70 80 90 100 110 120 LGEEEGEQAA GLAAVPQGGS AEEDSDIGPA TEEEEEEEEG NEAANFDLAV ATRRYPAAGI 130 140 150 160 170 180 GFVFLYLVHS LLRRLYHNDH IQIANRHLSR LMVGPHAAVP NLWDNPPLLL LSQRLGAGAA 190 200 210 220 230 240 APEGEGLGLI QEAASVQEAA SVPEPAVPAD LAEMAREPAE EAADEKPPEE AAEEKLTEEA 250 260 270 280 290 TEEPAAEEPT SEEAVAPEEV TKSQPEKWDE EAQDAAGEEE KEQEKEKDVE NKVKNSKGT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R. Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome." Chen Y.-T., Iseli C., Venditti C.A., Old L.J., Simpson A.J.G., Jongeneel C.V. Genes Chromosomes Cancer 45:392-400(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC008162 Genomic DNA. No translation available.
IPI	IPI00644400.
RefSeq	NP_001139190.1. NM_001145718.1.
UniGene	Hs.729566.
3D structure databases
ProteinModelPortal	P0C2W7.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000360360.
Polymorphism databases
DMDM	146286097.
Proteomic databases
PaxDb	P0C2W7.
PRIDE	P0C2W7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000371311; ENSP00000360360; ENSG00000236446.
GeneID	643311.
KEGG	hsa:643311.
UCSC	uc011muc.2. human.
Organism-specific databases
CTD	643311.
GeneCards	GC0XM120006.
HGNC	HGNC:33293. CT47B1.
HPA	HPA042483.
MIM	300790. gene.
neXtProt	NX_P0C2W7.
PharmGKB	PA164718327.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG125895.
HOGENOM	HOG000112037.
HOVERGEN	HBG094803.
InParanoid	P0C2W7.
OMA	FLYLVHS.
Gene expression databases
Bgee	P0C2W7.
Genevestigator	P0C2W7.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	643311.
NextBio	114736.
SOURCE	Search...

Entry information

Entry name

CT47B_HUMAN

Accession

Primary (citable) accession number: P0C2W7
Secondary accession number(s): A6NM97

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	April 3, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.