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Protein

Cancer/testis antigen 47B

Gene

CT47B1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Cancer/testis antigen 47B
Alternative name(s):
Cancer/testis antigen 47.13
Short name:
CT47.13
Gene namesi
Name:CT47B1
Synonyms:CT47.13
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:33293. CT47B1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164718327.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 299299Cancer/testis antigen 47BPRO_0000286433Add
BLAST

Proteomic databases

PaxDbiP0C2W7.
PRIDEiP0C2W7.

Expressioni

Gene expression databases

BgeeiP0C2W7.
GenevestigatoriP0C2W7.

Organism-specific databases

HPAiHPA042483.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360360.

Structurei

3D structure databases

ProteinModelPortaliP0C2W7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili270 – 29829Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi92 – 998Poly-Glu
Compositional biasi168 – 1714Poly-Leu

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG125895.
GeneTreeiENSGT00390000002253.
HOGENOMiHOG000112037.
HOVERGENiHBG094803.
InParanoidiP0C2W7.
OMAiFLYLVHS.
OrthoDBiEOG71CFNT.
PhylomeDBiP0C2W7.
TreeFamiTF342556.

Family and domain databases

InterProiIPR028930. CT47.
[Graphical view]
PANTHERiPTHR32157. PTHR32157. 1 hit.
PfamiPF15623. CT47. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C2W7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSATGDRHPT QGDQEAPVSQ EGAQAEAAGA GNQEGGDSGP DSSDMVPAAE
60 70 80 90 100
VVGVAGPVEG LGEEEGEQAA GLAAVPQGGS AEEDSDIGPA TEEEEEEEEG
110 120 130 140 150
NEAANFDLAV ATRRYPAAGI GFVFLYLVHS LLRRLYHNDH IQIANRHLSR
160 170 180 190 200
LMVGPHAAVP NLWDNPPLLL LSQRLGAGAA APEGEGLGLI QEAASVQEAA
210 220 230 240 250
SVPEPAVPAD LAEMAREPAE EAADEKPPEE AAEEKLTEEA TEEPAAEEPT
260 270 280 290
SEEAVAPEEV TKSQPEKWDE EAQDAAGEEE KEQEKEKDVE NKVKNSKGT
Length:299
Mass (Da):31,319
Last modified:May 1, 2007 - v1
Checksum:iE2FD8473EE062757
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008162 Genomic DNA. No translation available.
CCDSiCCDS48161.1.
RefSeqiNP_001139190.1. NM_001145718.1.
UniGeneiHs.729566.

Genome annotation databases

EnsembliENST00000371311; ENSP00000360360; ENSG00000236446.
GeneIDi643311.
KEGGihsa:643311.
UCSCiuc011muc.2. human.

Polymorphism databases

DMDMi146286097.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008162 Genomic DNA. No translation available.
CCDSiCCDS48161.1.
RefSeqiNP_001139190.1. NM_001145718.1.
UniGeneiHs.729566.

3D structure databases

ProteinModelPortaliP0C2W7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000360360.

Polymorphism databases

DMDMi146286097.

Proteomic databases

PaxDbiP0C2W7.
PRIDEiP0C2W7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371311; ENSP00000360360; ENSG00000236446.
GeneIDi643311.
KEGGihsa:643311.
UCSCiuc011muc.2. human.

Organism-specific databases

CTDi643311.
GeneCardsiGC0XM120006.
HGNCiHGNC:33293. CT47B1.
HPAiHPA042483.
MIMi300790. gene.
neXtProtiNX_P0C2W7.
PharmGKBiPA164718327.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG125895.
GeneTreeiENSGT00390000002253.
HOGENOMiHOG000112037.
HOVERGENiHBG094803.
InParanoidiP0C2W7.
OMAiFLYLVHS.
OrthoDBiEOG71CFNT.
PhylomeDBiP0C2W7.
TreeFamiTF342556.

Miscellaneous databases

GenomeRNAii643311.
NextBioi114736.
PROiP0C2W7.
SOURCEiSearch...

Gene expression databases

BgeeiP0C2W7.
GenevestigatoriP0C2W7.

Family and domain databases

InterProiIPR028930. CT47.
[Graphical view]
PANTHERiPTHR32157. PTHR32157. 1 hit.
PfamiPF15623. CT47. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome."
    Chen Y.-T., Iseli C., Venditti C.A., Old L.J., Simpson A.J.G., Jongeneel C.V.
    Genes Chromosomes Cancer 45:392-400(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiCT47B_HUMAN
AccessioniPrimary (citable) accession number: P0C2W7
Secondary accession number(s): A6NM97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.