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Protein

Cortexin-2

Gene

CTXN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Cortexin-2
Gene namesi
Name:CTXN2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:31109. CTXN2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei29 – 4921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134951739.

Polymorphism and mutation databases

BioMutaiCTXN2.
DMDMi145558892.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8181Cortexin-2PRO_0000284616Add
BLAST

Proteomic databases

PaxDbiP0C2S0.
PRIDEiP0C2S0.

Expressioni

Gene expression databases

BgeeiENSG00000233932.

Organism-specific databases

HPAiHPA053168.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000406145.

Structurei

3D structure databases

ProteinModelPortaliP0C2S0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cortexin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J1KT. Eukaryota.
ENOG410YVQ7. LUCA.
GeneTreeiENSGT00390000018468.
HOVERGENiHBG054879.
InParanoidiP0C2S0.
OMAiMSSSYCG.
OrthoDBiEOG091G15XU.
PhylomeDBiP0C2S0.
TreeFamiTF333403.

Family and domain databases

InterProiIPR020066. Cortexin.
[Graphical view]
PfamiPF11057. Cortexin. 1 hit.
[Graphical view]
ProDomiPD054489. Cortexin. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P0C2S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSTYCGNSS AKMSVNEVSA FSLTLEQKTG FAFVGILCIF LGLLIIRCFK
60 70 80
ILLDPYSSMP SSTWEDEVEE FDKGTFEYAL A
Length:81
Mass (Da):8,980
Last modified:April 17, 2007 - v1
Checksum:i52A01611040EC94D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537772 mRNA. No translation available.
AC066612 Genomic DNA. No translation available.
CCDSiCCDS45254.1.
RefSeqiNP_001139140.1. NM_001145668.1.
XP_005254435.1. XM_005254378.3.
XP_006720567.1. XM_006720504.2.
XP_011519855.1. XM_011521553.1.
UniGeneiHs.721408.

Genome annotation databases

EnsembliENST00000417307; ENSP00000406145; ENSG00000233932.
GeneIDi399697.
KEGGihsa:399697.
UCSCiuc001zwm.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537772 mRNA. No translation available.
AC066612 Genomic DNA. No translation available.
CCDSiCCDS45254.1.
RefSeqiNP_001139140.1. NM_001145668.1.
XP_005254435.1. XM_005254378.3.
XP_006720567.1. XM_006720504.2.
XP_011519855.1. XM_011521553.1.
UniGeneiHs.721408.

3D structure databases

ProteinModelPortaliP0C2S0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000406145.

Polymorphism and mutation databases

BioMutaiCTXN2.
DMDMi145558892.

Proteomic databases

PaxDbiP0C2S0.
PRIDEiP0C2S0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000417307; ENSP00000406145; ENSG00000233932.
GeneIDi399697.
KEGGihsa:399697.
UCSCiuc001zwm.2. human.

Organism-specific databases

CTDi399697.
GeneCardsiCTXN2.
HGNCiHGNC:31109. CTXN2.
HPAiHPA053168.
neXtProtiNX_P0C2S0.
PharmGKBiPA134951739.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J1KT. Eukaryota.
ENOG410YVQ7. LUCA.
GeneTreeiENSGT00390000018468.
HOVERGENiHBG054879.
InParanoidiP0C2S0.
OMAiMSSSYCG.
OrthoDBiEOG091G15XU.
PhylomeDBiP0C2S0.
TreeFamiTF333403.

Miscellaneous databases

GenomeRNAii399697.
PROiP0C2S0.

Gene expression databases

BgeeiENSG00000233932.

Family and domain databases

InterProiIPR020066. Cortexin.
[Graphical view]
PfamiPF11057. Cortexin. 1 hit.
[Graphical view]
ProDomiPD054489. Cortexin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiCTXN2_HUMAN
AccessioniPrimary (citable) accession number: P0C2S0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: September 7, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.