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Protein

60S ribosomal protein L31-B

Gene

RPL31B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.1 Publication

Miscellaneous

Present with 57500 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for eL31 in yeast.Curated

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • regulation of translational fidelity Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-32468-MONOMER
ReactomeiR-SCE-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SCE-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SCE-72689 Formation of a pool of free 40S subunits
R-SCE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SCE-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SCE-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L31-B1 Publication
Alternative name(s):
L34
Large ribosomal subunit protein eL31-B1 Publication
YL28
Gene namesi
Name:RPL31B1 Publication
Synonyms:RPL34, RPL34B
Ordered Locus Names:YLR406C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR406C
SGDiS000004398 RPL31B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002789681 – 11360S ribosomal protein L31-BAdd BLAST113

Proteomic databases

MaxQBiP0C2H9
PaxDbiP0C2H9
PRIDEiP0C2H9

PTM databases

iPTMnetiP0C2H9

Interactioni

Subunit structurei

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102).1 Publication1 Publication

Protein-protein interaction databases

BioGridi31663, 149 interactors
DIPiDIP-29387N
IntActiP0C2H9, 3 interactors
MINTiP0C2H9
STRINGi4932.YLR406C

Structurei

3D structure databases

ProteinModelPortaliP0C2H9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000005200
HOGENOMiHOG000216660
InParanoidiP0C2H9
KOiK02910
OMAiIKSVPHR
OrthoDBiEOG092C5QTG

Family and domain databases

CDDicd00463 Ribosomal_L31e, 1 hit
Gene3Di3.10.440.10, 1 hit
InterProiView protein in InterPro
IPR000054 Ribosomal_L31e
IPR020052 Ribosomal_L31e_CS
IPR023621 Ribosomal_L31e_dom_sf
PANTHERiPTHR10956 PTHR10956, 1 hit
PfamiView protein in Pfam
PF01198 Ribosomal_L31e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006030 Ribosomal_L31e, 1 hit
SMARTiView protein in SMART
SM01380 Ribosomal_L31e, 1 hit
SUPFAMiSSF54575 SSF54575, 1 hit
PROSITEiView protein in PROSITE
PS01144 RIBOSOMAL_L31E, 1 hit

Sequencei

Sequence statusi: Complete.

P0C2H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLKDVVTR EYTINLHKRL HGVSFKKRAP RAVKEIKKFA KLHMGTEDVR
60 70 80 90 100
LAPELNQAIW KRGVKGVEYR LRLRISRKRN EEEDAKNPLF SYVEPVLVAS
110
AKGLQTVVVE EDA
Length:113
Mass (Da):12,967
Last modified:March 6, 2007 - v1
Checksum:i351B5B6CA5DA8AED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19729 Genomic DNA Translation: AAB82359.1
BK006945 Genomic DNA Translation: DAA09705.1
PIRiS55962
RefSeqiNP_013510.3, NM_001182294.3

Genome annotation databases

EnsemblFungiiYLR406C; YLR406C; YLR406C
GeneIDi851122
KEGGisce:YLR406C

Similar proteinsi

Entry informationi

Entry nameiRL31B_YEAST
AccessioniPrimary (citable) accession number: P0C2H9
Secondary accession number(s): D6VZ39, P04649, Q3E7B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: March 6, 2007
Last modified: April 25, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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