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Protein

60S ribosomal protein L31-A

Gene

RPL31A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • regulation of translational fidelity Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29486-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L31-A
Alternative name(s):
L34
YL28
Gene namesi
Name:RPL31A
Synonyms:RPL34, RPL34A
Ordered Locus Names:YDL075W
ORF Names:D2478
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDL075W.
SGDiS000002233. RPL31A.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved2 Publications
Chaini2 – 11311260S ribosomal protein L31-APRO_0000153788Add
BLAST

Proteomic databases

MaxQBiP0C2H8.
PRIDEiP0C2H8.
TopDownProteomicsiP0C2H8.

PTM databases

iPTMnetiP0C2H8.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi31986. 51 interactions.
DIPiDIP-5135N.
IntActiP0C2H8. 1 interaction.
MINTiMINT-8285615.

Structurei

Secondary structure

1
113
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi9 – 157Combined sources
Helixi16 – 205Combined sources
Turni25 – 273Combined sources
Helixi28 – 4417Combined sources
Beta strandi49 – 513Combined sources
Helixi53 – 608Combined sources
Helixi64 – 663Combined sources
Beta strandi69 – 7911Combined sources
Beta strandi86 – 9510Combined sources
Beta strandi101 – 1033Combined sources
Beta strandi107 – 1093Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K5Ymodel-W6-83[»]
2WW9electron microscopy8.60M1-113[»]
2WWAelectron microscopy8.90M1-113[»]
2WWBelectron microscopy6.48M1-113[»]
3J6Xelectron microscopy6.10711-113[»]
3J6Yelectron microscopy6.10711-113[»]
3J77electron microscopy6.20811-113[»]
3J78electron microscopy6.30811-113[»]
3JCTelectron microscopy3.08d1-113[»]
4U3MX-ray3.00O1/o12-113[»]
4U3NX-ray3.20O1/o12-113[»]
4U3UX-ray2.90O1/o12-113[»]
4U4NX-ray3.10O1/o12-113[»]
4U4OX-ray3.60O1/o12-113[»]
4U4QX-ray3.00O1/o12-113[»]
4U4RX-ray2.80O1/o12-113[»]
4U4UX-ray3.00O1/o12-113[»]
4U4YX-ray3.20O1/o12-113[»]
4U4ZX-ray3.10O1/o12-113[»]
4U50X-ray3.20O1/o12-113[»]
4U51X-ray3.20O1/o12-113[»]
4U52X-ray3.00O1/o12-113[»]
4U53X-ray3.30O1/o12-113[»]
4U55X-ray3.20O1/o12-113[»]
4U56X-ray3.45O1/o12-113[»]
4U6FX-ray3.10O1/o12-113[»]
4V4Belectron microscopy11.70BW2-113[»]
4V6Ielectron microscopy8.80Bg1-113[»]
4V7Felectron microscopy8.70c1-113[»]
4V7RX-ray4.00Ba/Da1-113[»]
4V88X-ray3.00Bd/Dd1-113[»]
4V8Telectron microscopy8.10d1-113[»]
4V8Yelectron microscopy4.30Bd2-113[»]
4V8Zelectron microscopy6.60Bd2-113[»]
4V91electron microscopy3.70d1-113[»]
5APNelectron microscopy3.91d1-113[»]
5APOelectron microscopy3.41d1-113[»]
5DC3X-ray3.25O1/o12-113[»]
5FCIX-ray3.40O1/o12-113[»]
5FCJX-ray3.10O1/o12-113[»]
5FL8electron microscopy9.50d1-113[»]
5GAKelectron microscopy3.88f4-112[»]
5I4LX-ray3.10O1/o14-112[»]
ProteinModelPortaliP0C2H8.
SMRiP0C2H8. Positions 9-92.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0C2H8.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L31e family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000005200.
HOGENOMiHOG000216660.
InParanoidiP0C2H8.
KOiK02910.
OMAiDERIDTR.
OrthoDBiEOG092C5QTG.

Family and domain databases

CDDicd00463. Ribosomal_L31e. 1 hit.
Gene3Di3.10.440.10. 1 hit.
InterProiIPR000054. Ribosomal_L31e.
IPR020052. Ribosomal_L31e_CS.
IPR023621. Ribosomal_L31e_dom.
[Graphical view]
PANTHERiPTHR10956. PTHR10956. 1 hit.
PfamiPF01198. Ribosomal_L31e. 1 hit.
[Graphical view]
ProDomiPD006030. Ribosomal_L31e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM01380. Ribosomal_L31e. 1 hit.
[Graphical view]
SUPFAMiSSF54575. SSF54575. 1 hit.
PROSITEiPS01144. RIBOSOMAL_L31E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C2H8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLKDVVTR EYTINLHKRL HGVSFKKRAP RAVKEIKKFA KLHMGTDDVR
60 70 80 90 100
LAPELNQAIW KRGVKGVEYR LRLRISRKRN EEEDAKNPLF SYVEPVLVAS
110
AKGLQTVVVE EDA
Length:113
Mass (Da):12,953
Last modified:March 6, 2007 - v1
Checksum:i351B5ADD15DB3B5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01441 Genomic DNA. Translation: CAA25679.1.
Z74123 Genomic DNA. Translation: CAA98641.1.
BK006938 Genomic DNA. Translation: DAA11784.1.
PIRiS67611. R5BY1E.
RefSeqiNP_010208.1. NM_001180134.1.

Genome annotation databases

EnsemblFungiiYDL075W; YDL075W; YDL075W.
GeneIDi851484.
KEGGisce:YDL075W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01441 Genomic DNA. Translation: CAA25679.1.
Z74123 Genomic DNA. Translation: CAA98641.1.
BK006938 Genomic DNA. Translation: DAA11784.1.
PIRiS67611. R5BY1E.
RefSeqiNP_010208.1. NM_001180134.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K5Ymodel-W6-83[»]
2WW9electron microscopy8.60M1-113[»]
2WWAelectron microscopy8.90M1-113[»]
2WWBelectron microscopy6.48M1-113[»]
3J6Xelectron microscopy6.10711-113[»]
3J6Yelectron microscopy6.10711-113[»]
3J77electron microscopy6.20811-113[»]
3J78electron microscopy6.30811-113[»]
3JCTelectron microscopy3.08d1-113[»]
4U3MX-ray3.00O1/o12-113[»]
4U3NX-ray3.20O1/o12-113[»]
4U3UX-ray2.90O1/o12-113[»]
4U4NX-ray3.10O1/o12-113[»]
4U4OX-ray3.60O1/o12-113[»]
4U4QX-ray3.00O1/o12-113[»]
4U4RX-ray2.80O1/o12-113[»]
4U4UX-ray3.00O1/o12-113[»]
4U4YX-ray3.20O1/o12-113[»]
4U4ZX-ray3.10O1/o12-113[»]
4U50X-ray3.20O1/o12-113[»]
4U51X-ray3.20O1/o12-113[»]
4U52X-ray3.00O1/o12-113[»]
4U53X-ray3.30O1/o12-113[»]
4U55X-ray3.20O1/o12-113[»]
4U56X-ray3.45O1/o12-113[»]
4U6FX-ray3.10O1/o12-113[»]
4V4Belectron microscopy11.70BW2-113[»]
4V6Ielectron microscopy8.80Bg1-113[»]
4V7Felectron microscopy8.70c1-113[»]
4V7RX-ray4.00Ba/Da1-113[»]
4V88X-ray3.00Bd/Dd1-113[»]
4V8Telectron microscopy8.10d1-113[»]
4V8Yelectron microscopy4.30Bd2-113[»]
4V8Zelectron microscopy6.60Bd2-113[»]
4V91electron microscopy3.70d1-113[»]
5APNelectron microscopy3.91d1-113[»]
5APOelectron microscopy3.41d1-113[»]
5DC3X-ray3.25O1/o12-113[»]
5FCIX-ray3.40O1/o12-113[»]
5FCJX-ray3.10O1/o12-113[»]
5FL8electron microscopy9.50d1-113[»]
5GAKelectron microscopy3.88f4-112[»]
5I4LX-ray3.10O1/o14-112[»]
ProteinModelPortaliP0C2H8.
SMRiP0C2H8. Positions 9-92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31986. 51 interactions.
DIPiDIP-5135N.
IntActiP0C2H8. 1 interaction.
MINTiMINT-8285615.

PTM databases

iPTMnetiP0C2H8.

Proteomic databases

MaxQBiP0C2H8.
PRIDEiP0C2H8.
TopDownProteomicsiP0C2H8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDL075W; YDL075W; YDL075W.
GeneIDi851484.
KEGGisce:YDL075W.

Organism-specific databases

EuPathDBiFungiDB:YDL075W.
SGDiS000002233. RPL31A.

Phylogenomic databases

GeneTreeiENSGT00390000005200.
HOGENOMiHOG000216660.
InParanoidiP0C2H8.
KOiK02910.
OMAiDERIDTR.
OrthoDBiEOG092C5QTG.

Enzyme and pathway databases

BioCyciYEAST:G3O-29486-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

EvolutionaryTraceiP0C2H8.
PROiP0C2H8.

Family and domain databases

CDDicd00463. Ribosomal_L31e. 1 hit.
Gene3Di3.10.440.10. 1 hit.
InterProiIPR000054. Ribosomal_L31e.
IPR020052. Ribosomal_L31e_CS.
IPR023621. Ribosomal_L31e_dom.
[Graphical view]
PANTHERiPTHR10956. PTHR10956. 1 hit.
PfamiPF01198. Ribosomal_L31e. 1 hit.
[Graphical view]
ProDomiPD006030. Ribosomal_L31e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM01380. Ribosomal_L31e. 1 hit.
[Graphical view]
SUPFAMiSSF54575. SSF54575. 1 hit.
PROSITEiPS01144. RIBOSOMAL_L31E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL31A_YEAST
AccessioniPrimary (citable) accession number: P0C2H8
Secondary accession number(s): D6VRS4, P04649, Q3E7B8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: March 6, 2007
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

There are 2 genes for L31 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.