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P0C2H8

- RL31A_YEAST

UniProt

P0C2H8 - RL31A_YEAST

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Protein
60S ribosomal protein L31-A
Gene
RPL31A, RPL34, RPL34A, YDL075W, D2478
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. cytoplasmic translation Source: SGD
  2. regulation of translational fidelity Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29486-MONOMER.
ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L31-A
Alternative name(s):
L34
YL28
Gene namesi
Name:RPL31A
Synonyms:RPL34, RPL34A
Ordered Locus Names:YDL075W
ORF Names:D2478
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IV

Organism-specific databases

SGDiS000002233. RPL31A.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytosolic large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed2 Publications
Chaini2 – 11311260S ribosomal protein L31-A
PRO_0000153788Add
BLAST

Proteomic databases

MaxQBiP0C2H8.
PeptideAtlasiP0C2H8.
PRIDEiP0C2H8.

Expressioni

Gene expression databases

GenevestigatoriP0C2H8.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi31986. 109 interactions.
DIPiDIP-5135N.
IntActiP0C2H8. 1 interaction.
MINTiMINT-8285615.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K5Ymodel-W6-83[»]
1S1Ielectron microscopy11.70W2-113[»]
1VW8electron microscopy6.10e1-113[»]
1VWUelectron microscopy6.10e1-113[»]
2WW9electron microscopy8.60M1-113[»]
2WWAelectron microscopy8.90M1-113[»]
2WWBelectron microscopy6.48M1-113[»]
3IZSelectron microscopy-g1-113[»]
3J65electron microscopy8.70c1-113[»]
3O58X-ray4.00a1-113[»]
3O5HX-ray4.00a1-113[»]
3U5EX-ray3.00d1-113[»]
3U5IX-ray3.00d1-113[»]
4B6Aelectron microscopy8.10d1-113[»]
4BYNelectron microscopy4.30d2-113[»]
4BYUelectron microscopy6.60d2-113[»]
4CUWelectron microscopy3.70d1-113[»]
ProteinModelPortaliP0C2H8.
SMRiP0C2H8. Positions 4-112.

Miscellaneous databases

EvolutionaryTraceiP0C2H8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000005200.
HOGENOMiHOG000216660.
KOiK02910.
OMAiWRKEVIT.
OrthoDBiEOG7X0VW7.

Family and domain databases

Gene3Di3.10.440.10. 1 hit.
InterProiIPR000054. Ribosomal_L31e.
IPR020052. Ribosomal_L31e_CS.
IPR023621. Ribosomal_L31e_dom.
[Graphical view]
PANTHERiPTHR10956. PTHR10956. 1 hit.
PfamiPF01198. Ribosomal_L31e. 1 hit.
[Graphical view]
ProDomiPD006030. Ribosomal_L31e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54575. SSF54575. 1 hit.
PROSITEiPS01144. RIBOSOMAL_L31E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C2H8-1 [UniParc]FASTAAdd to Basket

« Hide

MAGLKDVVTR EYTINLHKRL HGVSFKKRAP RAVKEIKKFA KLHMGTDDVR    50
LAPELNQAIW KRGVKGVEYR LRLRISRKRN EEEDAKNPLF SYVEPVLVAS 100
AKGLQTVVVE EDA 113
Length:113
Mass (Da):12,953
Last modified:March 6, 2007 - v1
Checksum:i351B5ADD15DB3B5D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X01441 Genomic DNA. Translation: CAA25679.1.
Z74123 Genomic DNA. Translation: CAA98641.1.
BK006938 Genomic DNA. Translation: DAA11784.1.
PIRiS67611. R5BY1E.
RefSeqiNP_010208.1. NM_001180134.1.

Genome annotation databases

EnsemblFungiiYDL075W; YDL075W; YDL075W.
GeneIDi851484.
KEGGisce:YDL075W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X01441 Genomic DNA. Translation: CAA25679.1 .
Z74123 Genomic DNA. Translation: CAA98641.1 .
BK006938 Genomic DNA. Translation: DAA11784.1 .
PIRi S67611. R5BY1E.
RefSeqi NP_010208.1. NM_001180134.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1K5Y model - W 6-83 [» ]
1S1I electron microscopy 11.70 W 2-113 [» ]
1VW8 electron microscopy 6.10 e 1-113 [» ]
1VWU electron microscopy 6.10 e 1-113 [» ]
2WW9 electron microscopy 8.60 M 1-113 [» ]
2WWA electron microscopy 8.90 M 1-113 [» ]
2WWB electron microscopy 6.48 M 1-113 [» ]
3IZS electron microscopy - g 1-113 [» ]
3J65 electron microscopy 8.70 c 1-113 [» ]
3O58 X-ray 4.00 a 1-113 [» ]
3O5H X-ray 4.00 a 1-113 [» ]
3U5E X-ray 3.00 d 1-113 [» ]
3U5I X-ray 3.00 d 1-113 [» ]
4B6A electron microscopy 8.10 d 1-113 [» ]
4BYN electron microscopy 4.30 d 2-113 [» ]
4BYU electron microscopy 6.60 d 2-113 [» ]
4CUW electron microscopy 3.70 d 1-113 [» ]
ProteinModelPortali P0C2H8.
SMRi P0C2H8. Positions 4-112.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31986. 109 interactions.
DIPi DIP-5135N.
IntActi P0C2H8. 1 interaction.
MINTi MINT-8285615.

Proteomic databases

MaxQBi P0C2H8.
PeptideAtlasi P0C2H8.
PRIDEi P0C2H8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YDL075W ; YDL075W ; YDL075W .
GeneIDi 851484.
KEGGi sce:YDL075W.

Organism-specific databases

SGDi S000002233. RPL31A.

Phylogenomic databases

GeneTreei ENSGT00390000005200.
HOGENOMi HOG000216660.
KOi K02910.
OMAi WRKEVIT.
OrthoDBi EOG7X0VW7.

Enzyme and pathway databases

BioCyci YEAST:G3O-29486-MONOMER.
Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Miscellaneous databases

EvolutionaryTracei P0C2H8.
NextBioi 968804.

Gene expression databases

Genevestigatori P0C2H8.

Family and domain databases

Gene3Di 3.10.440.10. 1 hit.
InterProi IPR000054. Ribosomal_L31e.
IPR020052. Ribosomal_L31e_CS.
IPR023621. Ribosomal_L31e_dom.
[Graphical view ]
PANTHERi PTHR10956. PTHR10956. 1 hit.
Pfami PF01198. Ribosomal_L31e. 1 hit.
[Graphical view ]
ProDomi PD006030. Ribosomal_L31e. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54575. SSF54575. 1 hit.
PROSITEi PS01144. RIBOSOMAL_L31E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The primary structure of a gene encoding yeast ribosomal protein L34."
    Schaap P.J., Molenaar C.M.T., Mager W.H., Planta R.J.
    Curr. Genet. 9:47-52(1984)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Carlsbergensis.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes."
    Otaka E., Higo K., Itoh T.
    Mol. Gen. Genet. 195:544-546(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: PARTIAL PROTEIN SEQUENCE OF 2-51, CLEAVAGE OF INITIATOR METHIONINE.
  5. "The action of N-terminal acetyltransferases on yeast ribosomal proteins."
    Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
    J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: CLEAVAGE OF INITIATOR METHIONINE.
  6. "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions."
    Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J.
    Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING OF 6-83, ELECTRON MICROSCOPY.
  7. "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation."
    Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.
    EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY.
  8. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
    Planta R.J., Mager W.H.
    Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, SUBUNIT.
  9. "Crystal structure of the eukaryotic ribosome."
    Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
    Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
  10. Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.

Entry informationi

Entry nameiRL31A_YEAST
AccessioniPrimary (citable) accession number: P0C2H8
Secondary accession number(s): D6VRS4, P04649, Q3E7B8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: March 6, 2007
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

There are 2 genes for L31 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3

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