60S ribosomal protein L27-A - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Contribute

Send feedback

Read comments (?) or add your own

P0C2H6 (RL27A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 51. History...

Clusters with 100%, 90%, 50% identity |

Documents (5) |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
60S ribosomal protein L27-A

Gene names

Name:	RPL27A
Synonyms:	RPL27
Ordered Locus Names:	YHR010W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.5.
Miscellaneous	Present with 7380 molecules/cell in log phase SD medium. There are 2 genes for L27 in yeast.
Sequence similarities	Belongs to the ribosomal protein L27e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Traceable author statement Ref.3. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Traceable author statement Ref.3. Source: SGD
Molecular_function	structural constituent of ribosome Traceable author statement Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

Removed Ref.4

Chain

2 – 136

135

60S ribosomal protein L27-A

PRO_0000126092

Sequences

Sequence

Length

Mass (Da)

Tools

P0C2H6 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: F3924B039AA2D85D
Show »

FASTA

136

15,531

        10         20         30         40         50         60 
MAKFLKAGKV AVVVRGRYAG KKVVIVKPHD EGSKSHPFGH ALVAGIERYP LKVTKKHGAK 

        70         80         90        100        110        120 
KVAKRTKIKP FIKVVNYNHL LPTRYTLDVE AFKSVVSTET FEQPSQREEA KKVVKKAFEE 

       130 
RHQAGKNQWF FSKLRF

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U10400 Genomic DNA. Translation: AAB68944.1.
BK006934 Genomic DNA. Translation: DAA06699.1.

PIR

S46790.

RefSeq

NP_011874.1. NM_001179140.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IZS	electron microscopy	-	a	1-136	[»]
3U5E	X-ray	3.00	Z	1-136	[»]
3U5I	X-ray	3.00	Z	1-136	[»]
4B6A	electron microscopy	8.10	Z	1-136	[»]

ProteinModelPortal

P0C2H6.

SMR

P0C2H6. Positions 2-136.

ModBase

Search...

Protein-protein interaction databases

MINT

MINT-1325160.

STRING

4932.YHR010W.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YHR010W; YHR010W; YHR010W.

GeneID

856401.

KEGG

sce:YHR010W.

Organism-specific databases

SGD

S000001052. RPL27A.

Phylogenomic databases

GeneTree

ENSGT00390000010721.

HOGENOM

HOG000210138.

K02901.

OMA

FNYNHLM.

OrthoDB

EOG496328.

Gene expression databases

Genevestigator

P0C2H6.

GermOnline

YHR010W. Saccharomyces cerevisiae.

Family and domain databases

Gene3D

2.30.30.30. 1 hit.

InterPro

IPR014722. Rib_L2_dom2.
IPR001141. Ribosomal_L27e.
IPR018262. Ribosomal_L27e_CS.
[Graphical view]

PANTHER

PTHR10497. PTHR10497. 1 hit.

Pfam

PF01777. Ribosomal_L27e. 1 hit.
[Graphical view]

ProDom

PD009396. Ribosomal_L27e. 1 hit.
[Graphical view] [Entries sharing at least one domain]

PROSITE

PS01107. RIBOSOMAL_L27E. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

981934.

Entry information

Entry name

RL27A_YEAST

Accession

Primary (citable) accession number: P0C2H6
Secondary accession number(s): D3DKV5, P38706

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program