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Protein

Conotoxin Bt11.1

Gene
N/A
Organism
Conus betulinus (Beech cone)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel impairing toxin, Neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Bt11.1
OrganismiConus betulinus (Beech cone)
Taxonomic identifieri89764 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConusDendroconus

Organism-specific databases

ConoServeri1454 Bt11.1 precursor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
PropeptideiPRO_000026267321 – 35Sequence analysisAdd BLAST15
ChainiPRO_000026267438 – 73Conotoxin Bt11.1Add BLAST36

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi39 ↔ 53By similarity
Disulfide bondi46 ↔ 58By similarity
Disulfide bondi52 ↔ 63By similarity
Disulfide bondi57 ↔ 70By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Proteomic databases

PRIDEiP0C251

Expressioni

Tissue specificityi

Expressed by the venom duct.

Structurei

3D structure databases

SMRiP0C251
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The cysteine framework is XI (C-C-CC-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin I1 superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR013141 Conotoxin-I_CS
PROSITEiView protein in PROSITE
PS60019 I_CONOTOXIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C251-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLCVAFLLV LVILPSVIGG KPSERTLSGA TRRGDRRMCL SLGQRCERHS
60 70
NCCGYLCCFY DKCVVTAIGC GHY
Length:73
Mass (Da):8,031
Last modified:November 28, 2006 - v1
Checksum:i9666ED648DBD8965
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ959108 Genomic DNA Translation: ADB93078.1

Similar proteinsi

Entry informationi

Entry nameiCI1B1_CONBE
AccessioniPrimary (citable) accession number: P0C251
Secondary accession number(s): D6C4G6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: May 23, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

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