P0C1G8 (PSA4A_ORYSJ) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 45.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Proteasome subunit alpha type-4-1 EC=3.4.25.1 Alternative name(s): 20S proteasome alpha subunit C 20S proteasome subunit alpha-3 | |||||||||||
| Gene names |
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| Organism | Oryza sativa subsp. japonica (Rice) | |||||||||||
| Taxonomic identifier | 39947 [NCBI] | |||||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza |
Protein attributes
| Sequence length | 250 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
| Catalytic activity | Cleavage of peptide bonds with very broad specificity. |
| Subunit structure | The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity. |
| Subcellular location | |
| Sequence similarities | Belongs to the peptidase T1A family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm Nucleus Proteasome |
| Molecular function | Hydrolase Protease Threonine protease |
| Gene Ontology (GO) | |
| Biological process | ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell proteasome core complex, alpha-subunit complexInferred from electronic annotation. Source: InterPro |
| Molecular function | threonine-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 250 | 250 | Proteasome subunit alpha type-4-1 | PRO_0000124112 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Primary structural features of the 20S proteasome subunits of rice (Oryza sativa)." Sassa H., Oguchi S., Inoue T., Hirano H. Gene 250:61-66(2000) [PubMed: 10854779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Nipponbare. |
| [2] | "The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare. |
| [3] | "The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare. |
| [4] | "The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. Yang H.PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AB026560 mRNA. Translation: BAA96831.1. AP002069 Genomic DNA. Translation: BAA95822.1. AP002069 Genomic DNA. Translation: BAA95832.1. AP008212 Genomic DNA. Translation: BAF18867.1. CM000143 Genomic DNA. Translation: EAZ36014.1. |
| RefSeq | NP_001056953.1. NM_001063488.2. |
| UniGene | Os.88355. |
3D structure databases | |
| ProteinModelPortal | P0C1G8. |
| SMR | P0C1G8. Positions 2-220. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P0C1G8. |
Protein family/group databases | |
| MEROPS | T01.973. |
Proteomic databases | |
| PRIDE | P0C1G8. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | LOC_Os06g07878.1; LOC_Os06g07878.1; LOC_Os06g07878. LOC_Os06g07978.1; LOC_Os06g07978.1; LOC_Os06g07978. |
| GeneID | 4340285. |
| KEGG | osa:4340285. |
Organism-specific databases | |
| Gramene | Q9LE92. |
Phylogenomic databases | |
| GeneTree | EPGT00050000005277. |
| HOGENOM | HBG499923. |
| OMA | MARRYDS. |
| PhylomeDB | P0C1G8. |
| ProtClustDB | CLSN2685293. |
Family and domain databases | |
| InterPro | IPR000426. Proteasome_asu_N. IPR023332. Proteasome_suA-type. IPR001353. Proteasome_sua/b. [Graphical view] |
| KO | K02728. |
| Pfam | PF00227. Proteasome. 1 hit. PF10584. Proteasome_A_N. 1 hit. [Graphical view] |
| SMART | SM00948. Proteasome_A_N. 1 hit. [Graphical view] |
| PROSITE | PS00388. PROTEASOME_A_1. 1 hit. PS51475. PROTEASOME_A_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PSA4A_ORYSJ | ||||||||
| Accession | Primary (citable) accession number: P0C1G8 Secondary accession number(s): Q0DE56, Q9LE92, Q9XIZ9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Peptidase families Classification of peptidase families and list of entries |
| Oryza sativa (rice) Index of Oryza sativa entries and their corresponding gene designations |
| SIMILARITY comments Index of protein domains and families |

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