ID   PNTAB_RHORU             Reviewed;         139 AA.
AC   P0C187; Q59762; Q59764;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   16-JUN-2009, entry version 14.
DE   RecName: Full=NAD(P) transhydrogenase subunit alpha part 2;
DE            EC=1.6.1.2;
DE   AltName: Full=Nicotinamide nucleotide transhydrogenase subunit alpha 2;
DE   AltName: Full=Pyridine nucleotide transhydrogenase subunit alpha 2;
DE   AltName: Full=Proton-translocating transhydrogenase component 2;
DE   AltName: Full=dII;
GN   Name=pntAB; Synonyms=nntA2;
OS   Rhodospirillum rubrum.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=1085;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=95146505; PubMed=7844118; DOI=10.1007/BF00762784;
RA   Yamaguchi M., Hatefi Y.;
RT   "Energy-transducing nicotinamide nucleotide transhydrogenase:
RT   nucleotide sequences of the genes and predicted amino acid sequences
RT   of the subunits of the enzyme from Rhodospirillum rubrum.";
RL   J. Bioenerg. Biomembr. 26:435-445(1994).
CC   -!- FUNCTION: The transhydrogenation between NADH and NADP is coupled
CC       to respiration and ATP hydrolysis and functions as a proton pump
CC       across the membrane (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH.
CC   -!- SUBUNIT: Complex of an alpha and a beta chain; in Rhodospirillum,
CC       the alpha chain seems to be made of two subunits.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
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DR   EMBL; U01158; AAC43256.1; -; Genomic_DNA.
DR   TCDB; 3.D.2.2.1; proton-translocating transhydrogenase (PTH) family.
DR   BRENDA; 1.6.1.2; 1671.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008750; F:NAD(P)+ transhydrogenase (AB-specific) acti...; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; NAS:UniProtKB.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; NAD; NADP;
KW   Oxidoreductase; Transmembrane.
FT   CHAIN         1    139       NAD(P) transhydrogenase subunit alpha
FT                                part 2.
FT                                /FTId=PRO_0000199021.
FT   TRANSMEM     49     69       Potential.
FT   TRANSMEM     78     98       Potential.
FT   TRANSMEM    107    127       Potential.
SQ   SEQUENCE   139 AA;  14889 MW;  04742D87817A8879 CRC64;
     MEDKNILVEG FNQLSQQALE LSQHAQALAL QASHAVLPAA AATEGASEFW WLMTVFVLAC
     FIGFYVVWSV TPALHSPLMG VTNAISSVIV VGALIATGPE AFSASKVLGF FAILLASVNI
     FGGFIVTQRM LAMFKKKQK
//