P0C125 (SECB_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	BruAb1_2047

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity. HAMAP MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00821.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 163	163	Protein-export protein secB HAMAP MF_00821		PRO_0000055352

Sequences

	Sequence		Length	Mass (Da)
	P0C125 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 79D31398E1690A28	FASTA	163	17,878
	10 20 30 40 50 60 MSDKAAGETK NGNGATTEPS LNILAQYVKD LSFESPGAPL SLRPREKAPS ININVNVNAN 70 80 90 100 110 120 PLSETDFDVV LTLEAKAVDG KDILFNTELV YGGVFRIQGI PQEHMLPLLF IECPRLLFPF 130 140 150 160 ARQIIADATR NGGYPPLMID PIDFAQMFQQ RMAEEQAKSA VKS

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX75348.1.
RefSeq	YP_222709.1. NC_006932.1.
3D structure databases
ProteinModelPortal	P0C125.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3339678.
GenomeReviews	Gene locus BruAb1_2047 in contig AE017223_GR.
KEGG	bmb:BruAb1_2047.
PATRIC	17825943. VBIBruAbo15061_2159.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG294212.
OMA	GFPPLMI.
PhylomeDB	P0C125.
ProtClustDB	PRK05751.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_2047-MONOMER.
Family and domain databases
HAMAP	MF_00821. SecB. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
KO	K03071.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. SecB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_BRUAB

Accession

Primary (citable) accession number: P0C125
Secondary accession number(s): Q57AI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program