Reviewed, UniProtKB/Swiss-Prot P0C121 (URE31_BRUAB)

Names and origin

Protein names

Recommended name:
    Urease subunit gamma 1
    EC=3.5.1.5
Alternative name(s):
    Urea amidohydrolase subunit gamma 1

Gene names

Name:	ureA1
Synonyms:	ureA, ureA-1
Ordered Locus Names:	BruAb1_0294

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP MF_00739
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_00739
Subunit structure	Heterotrimer of ureA (gamma), ureB (beta) and ureC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the urease gamma subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	urea metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel ion binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Urease subunit gamma 1 HAMAP MF_00739		PRO_0000097998

Sequences

	Sequence		Length	Mass (Da)
	P0C121-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 98BAAAE973961FE1	FASTA	100	11,103
	10 20 30 40 50 60 MNLTPREKDK LLIAMAAMVA RRRLERGVKL NHPEAIALVS DFVVEGARDG RTVAELMEAG 70 80 90 100 AHVITREQVM DGVAEMIRDI QVEATFPDGT KLVTVHEPIR

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73697.1.
RefSeq	YP_221058.1.
3D structure databases
SMR	P0C121. Positions 1-99.
ModBase	Search...
Genome annotation databases
GeneID	3340566.
GenomeReviews	Gene locus BruAb1_0294 in contig AE017223_GR.
KEGG	bmb:BruAb1_0294.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P0C121.
OMA	EAIAIIS
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0294-MON.
BRENDA	3.5.1.5. 575.
Family and domain databases
HAMAP	MF_00739. [Tree]
InterPro	IPR002026. Urease_alpha/gamma. IPR012010. Urease_gamma. [Graphical view]
Gene3D	G3DSA:3.30.280.10. Urease_gamma_reg. 1 hit.
Pfam	PF00547. Urease_gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001223. Urease_gamma. 1 hit.
ProDom	PD002319. Urease_gamma_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00193. urease_gam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE31_BRUAB

Accession

Primary (citable) accession number: P0C121
Secondary accession number(s): Q57F87, Q93T83

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	November 24, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)