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P0C121 (URE31_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Urease subunit gamma 1
EC=3.5.1.5
Alternative name(s):
Urea amidohydrolase subunit gamma 1
Gene names
Name:ureA1
Synonyms:ureA, ureA-1
Ordered Locus Names:BruAb1_0294
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length100 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Urea + H2O = CO2 + 2 NH3. HAMAP MF_00739

Pathway

Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_00739

Subunit structure

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.

Subcellular location

Cytoplasm By similarity HAMAP MF_00739.

Sequence similarities

Belongs to the urease gamma subunit family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processurea metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnickel cation binding

Inferred from electronic annotation. Source: InterPro

urease activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 100100Urease subunit gamma 1 HAMAP MF_00739
PRO_0000097998

Sequences

Sequence LengthMass (Da)Tools
P0C121 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 98BAAAE973961FE1

FASTA10011,103
        10         20         30         40         50         60 
MNLTPREKDK LLIAMAAMVA RRRLERGVKL NHPEAIALVS DFVVEGARDG RTVAELMEAG 

        70         80         90        100 
AHVITREQVM DGVAEMIRDI QVEATFPDGT KLVTVHEPIR

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017223 Genomic DNA. Translation: AAX73697.1.
RefSeqYP_221058.1. NC_006932.1.

3D structure databases

ProteinModelPortalP0C121.
SMRP0C121. Positions 1-99.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3340566.
GenomeReviewsGene locus BruAb1_0294 in contig AE017223_GR.
KEGGbmb:BruAb1_0294.
PATRIC17822166. VBIBruAbo15061_0321.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG286300.
OMAHVITRDQ.
ProtClustDBPRK13241.

Enzyme and pathway databases

BioCycBABO262698:BRUAB1_0294-MONOMER.

Family and domain databases

HAMAPMF_00739. Urease_gamma.
[Tree]
InterProIPR002026. Urease_gamma/gamma-beta_su.
IPR012010. Urease_gamma_su.
[Graphical view]
Gene3DG3DSA:3.30.280.10. Urease_gamma_reg. 1 hit.
KOK01430.
PfamPF00547. Urease_gamma. 1 hit.
[Graphical view]
PIRSFPIRSF001223. Urease_gamma. 1 hit.
ProDomPD002319. Urease_gamma_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54111. Urease_gamma_reg. 1 hit.
TIGRFAMsTIGR00193. Urease_gam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameURE31_BRUAB
AccessionPrimary (citable) accession number: P0C121
Secondary accession number(s): Q57F87, Q93T83
Entry history
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: February 7, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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