Reviewed, UniProtKB/Swiss-Prot P0C108 (IF1_BRUAB)

Names and origin

Protein names

Recommended name:
    Translation initiation factor IF-1

Gene names

Name:	infA
Ordered Locus Names:	BruAb1_0277

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3. HAMAP MF_00075
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the IF-1 family. Contains 1 S1-like domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational initiation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: HAMAP translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 72	72	Translation initiation factor IF-1 HAMAP MF_00075		PRO_0000095752
Regions
	Domain	1 – 72	72	S1-like

Sequences

	Sequence		Length	Mass (Da)
	P0C108-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 67D1320EB09AE093	FASTA	72	8,372
	10 20 30 40 50 60 MAKEEVLEFP GVVTELLPNA MFRVKLENEH EIIAHTAGRM RKNRIRVLAG DKVLVEMTPY 70 DLTKGRITYR FK

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73682.1.
RefSeq	YP_221043.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339538.
GenomeReviews	Gene locus BruAb1_0277 in contig AE017223_GR.
KEGG	bmb:BruAb1_0277.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P0C108.
OMA	VQLDAGH
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0277-MON.
Family and domain databases
HAMAP	MF_00075. [Tree]
InterPro	IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR006196. S1_IF1. IPR004368. TIF_IF1. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
Pfam	PF01176. eIF-1a. 1 hit. [Graphical view]
TIGRFAMs	TIGR00008. infA. 1 hit.
PROSITE	PS50832. S1_IF1_TYPE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF1_BRUAB

Accession

Primary (citable) accession number: P0C108
Secondary accession number(s): P62922 , Q57FA2, Q8YF56, Q9ACA6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	November 24, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)