P0C107 (HFQ_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein hfq

Gene names

Name:	hfq
Ordered Locus Names:	BruAb1_1117

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs By similarity. HAMAP-Rule MF_00436
Subunit structure	Homohexamer By similarity.
Sequence similarities	Belongs to the hfq family.

Ontologies

Keywords
Biological process	Stress response
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 78	78	Protein hfq HAMAP-Rule MF_00436		PRO_0000095627

Sequences

	Sequence		Length	Mass (Da)
	P0C107 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 0D27DBD9CA161BD0	FASTA	78	8,854
	10 20 30 40 50 60 MAERSQNLQD LFLNSVRKQK ISLTIFLING VKLTGIVTSF DNFCVLLRRD GHSQLVYKHA 70 ISTIMPSQPV QMFEGEEA

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX74458.1.
RefSeq	YP_221819.1. NC_006932.1.
3D structure databases
ProteinModelPortal	P0C107.
SMR	P0C107. Positions 7-71.
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb1_1117.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX74458; AAX74458; BruAb1_1117.
GeneID	3340039.
KEGG	bmb:BruAb1_1117.
PATRIC	17823923. VBIBruAbo15061_1184.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1923.
HOGENOM	HOG000004931.
KO	K03666.
OMA	PYLNVLR.
ProtClustDB	PRK00395.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-1139-MONOMER.
Family and domain databases
HAMAP	MF_00436. Lsm_Hfq.
InterPro	IPR005001. Hfq. IPR010920. LSM_dom. IPR001163. Ribonucl_LSM. [Graphical view]
Pfam	PF01423. LSM. 1 hit. [Graphical view]
SUPFAM	SSF50182. Sm_like_riboprot. 1 hit.
TIGRFAMs	TIGR02383. Hfq. 1 hit.
ProtoNet	Search...

Entry information

Entry name

HFQ_BRUAB

Accession

Primary (citable) accession number: P0C107
Secondary accession number(s): P0A3G9, Q57D26, Q9XBW1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program