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P0C107 (HFQ_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-binding protein Hfq
Gene names
Name:hfq
Ordered Locus Names:BruAb1_1117
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs By similarity. HAMAP-Rule MF_00436

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_00436

Sequence similarities

Belongs to the Hfq family.

Ontologies

Keywords
   Biological processStress response
   LigandRNA-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7878RNA-binding protein Hfq HAMAP-Rule MF_00436
PRO_0000095627

Sequences

Sequence LengthMass (Da)Tools
P0C107 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 0D27DBD9CA161BD0

FASTA788,854
        10         20         30         40         50         60 
MAERSQNLQD LFLNSVRKQK ISLTIFLING VKLTGIVTSF DNFCVLLRRD GHSQLVYKHA 

        70 
ISTIMPSQPV QMFEGEEA 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX74458.1.
RefSeqYP_221819.1. NC_006932.1.

3D structure databases

ProteinModelPortalP0C107.
SMRP0C107. Positions 7-71.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_1117.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX74458; AAX74458; BruAb1_1117.
GeneID3340039.
KEGGbmb:BruAb1_1117.
PATRIC17823923. VBIBruAbo15061_1184.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1923.
HOGENOMHOG000004931.
KOK03666.
OMAQDPYLNV.
OrthoDBEOG68SW3W.
ProtClustDBPRK00395.

Enzyme and pathway databases

BioCycBABO262698:GJC2-1139-MONOMER.

Family and domain databases

HAMAPMF_00436. Hfq.
InterProIPR005001. Hfq.
IPR010920. LSM_dom.
IPR001163. Ribonucl_LSM.
[Graphical view]
PfamPF01423. LSM. 1 hit.
[Graphical view]
SUPFAMSSF50182. SSF50182. 1 hit.
TIGRFAMsTIGR02383. Hfq. 1 hit.
ProtoNetSearch...

Other

PROP0C107.

Entry information

Entry nameHFQ_BRUAB
AccessionPrimary (citable) accession number: P0C107
Secondary accession number(s): P0A3G9, Q57D26, Q9XBW1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: February 7, 2006
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names