Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P0C102

- CDSA_BRUAB

UniProt

P0C102 - CDSA_BRUAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciBABO262698:GJC2-1185-MONOMER.
RETL1328306-WGS:GSTH-1976-MONOMER.
UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:BruAb1_1163
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 270270Phosphatidate cytidylyltransferasePRO_0000090727Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi262698.BruAb1_1163.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalSequence AnalysisAdd
BLAST
Transmembranei53 – 7321HelicalSequence AnalysisAdd
BLAST
Transmembranei76 – 9621HelicalSequence AnalysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence AnalysisAdd
BLAST
Transmembranei126 – 14621HelicalSequence AnalysisAdd
BLAST
Transmembranei183 – 20321HelicalSequence AnalysisAdd
BLAST
Transmembranei248 – 26821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
HOGENOMiHOG000006169.
KOiK00981.
OMAiGFILYEW.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C102-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNLQTRIIT AIVLGTITLW LTWVGGVGFT LFSIAIGLAM FYEWTELSAT
60 70 80 90 100
RQTAFSRLFG WAWLIVTGIL LILDRGALLT IGFLVAGCAI LLVTQWKSGR
110 120 130 140 150
GWPAAGLFYA GFSALSLSLL RGDEPFGFTT IVFLFAVVWS TDITAYFNGR
160 170 180 190 200
ALGGPKLAPR FSPNKTWSGA IGGAAAAVAG GLLVASLVAA PGGWGVPVLA
210 220 230 240 250
LLLSIVSQIG DLAESWVKRQ FGAKDSGRLL PGHGGVLDRV DGLVAAAALL
260 270
YLFGAIFAEP DVLSAIFFSF
Length:270
Mass (Da):28,448
Last modified:February 7, 2006 - v1
Checksum:i47F253043415FF06
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017223 Genomic DNA. Translation: AAX74502.1.
RefSeqiYP_221863.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX74502; AAX74502; BruAb1_1163.
GeneIDi3339837.
KEGGibmb:BruAb1_1163.
PATRICi17824012. VBIBruAbo15061_1228.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017223 Genomic DNA. Translation: AAX74502.1 .
RefSeqi YP_221863.1. NC_006932.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb1_1163.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX74502 ; AAX74502 ; BruAb1_1163 .
GeneIDi 3339837.
KEGGi bmb:BruAb1_1163.
PATRICi 17824012. VBIBruAbo15061_1228.

Phylogenomic databases

eggNOGi COG0575.
HOGENOMi HOG000006169.
KOi K00981.
OMAi GFILYEW.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .
BioCyci BABO262698:GJC2-1185-MONOMER.
RETL1328306-WGS:GSTH-1976-MONOMER.

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiCDSA_BRUAB
AccessioniPrimary (citable) accession number: P0C102
Secondary accession number(s): Q57CY2, Q59173
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: February 7, 2006
Last modified: October 29, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3