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Protein

10 kDa chaperonin

Gene

groS

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperonin
Alternative name(s):
11.2 kDa stress response protein
GroES protein
Heat shock protein 10
Short name:
HSP10
Protein Cpn10
Gene namesi
Name:groS
Synonyms:groES, hypA, mopB
Ordered Locus Names:CT_111
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000431 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10210210 kDa chaperoninPRO_0000174731Add
BLAST

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi272561.CT111.

Structurei

3D structure databases

ProteinModelPortaliP0C0Z8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.Curated

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
InParanoidiP0C0Z8.
KOiK04078.
OMAiVMGENEI.
OrthoDBiEOG6GFGSD.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C0Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQATTLKI KPLGDRILVK REEEASTARG GIILPDTAKK KQDRAEVLAL
60 70 80 90 100
GTGKKDDKGQ QLPFEVQVGN IVLIDKYSGQ ELTVEGEEYV IVQMSEVIAV

LQ
Length:102
Mass (Da):11,182
Last modified:February 7, 2006 - v1
Checksum:i1798FAD70F903AB6
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti48 – 481L → V in strain: L2.
Natural varianti65 – 651E → V in strain: L2.
Natural varianti70 – 701N → D in strain: L2.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M58027 Genomic DNA. Translation: AAA23127.1.
AE001273 Genomic DNA. Translation: AAC67702.1.
PIRiB60273.
B71555.
RefSeqiNP_219614.1. NC_000117.1.
WP_009871458.1. NC_000117.1.

Genome annotation databases

EnsemblBacteriaiAAC67702; AAC67702; CT_111.
GeneIDi884062.
KEGGictr:CT_111.
PATRICi20379709. VBIChlTra43535_0121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M58027 Genomic DNA. Translation: AAA23127.1.
AE001273 Genomic DNA. Translation: AAC67702.1.
PIRiB60273.
B71555.
RefSeqiNP_219614.1. NC_000117.1.
WP_009871458.1. NC_000117.1.

3D structure databases

ProteinModelPortaliP0C0Z8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272561.CT111.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC67702; AAC67702; CT_111.
GeneIDi884062.
KEGGictr:CT_111.
PATRICi20379709. VBIChlTra43535_0121.

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
InParanoidiP0C0Z8.
KOiK04078.
OMAiVMGENEI.
OrthoDBiEOG6GFGSD.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequence of the gene for heat shock protein 60 from Chlamydia trachomatis and immunological reactivity of the protein."
    Cerrone M.C., Ma J.J., Stephens R.S.
    Infect. Immun. 59:79-90(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: L2.
  2. "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."
    Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.
    Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D/UW-3/Cx.

Entry informationi

Entry nameiCH10_CHLTR
AccessioniPrimary (citable) accession number: P0C0Z8
Secondary accession number(s): O84113
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: February 7, 2006
Last modified: June 8, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.