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P0C0X3

- TFB5_CANAL

UniProt

P0C0X3 - TFB5_CANAL

Protein

RNA polymerase II transcription factor B subunit 5

Gene

TFB5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Component of the general transcription and DNA repair factor IIH (TFIIH), which is essential for both basal and activated transcription, as well as for nucleotide excision repair (NER) of DNA. TFB5 is required for stable recruitment of TFIIH to a promoter, but not for stability of TFIIH subunits By similarity.By similarity

    GO - Biological processi

    1. nucleotide-excision repair Source: InterPro
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    DNA damage, DNA repair, Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase II transcription factor B subunit 5
    Alternative name(s):
    General transcription and DNA repair factor IIH subunit 5
    Short name:
    TFIIH subunit 5
    Gene namesi
    Name:TFB5
    ORF Names:CaO19.11919.1, CaO19.4439.1
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAF0007011. orf19.4439.1.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. core TFIIH complex Source: InterPro

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 6969RNA polymerase II transcription factor B subunit 5PRO_0000119278Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the core TFIIH complex.By similarity

    Protein-protein interaction databases

    STRINGi5476.CAF0007011.

    Structurei

    3D structure databases

    ProteinModelPortaliP0C0X3.
    SMRiP0C0X3. Positions 4-65.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TFB5 family.Curated

    Phylogenomic databases

    eggNOGiNOG148452.
    OrthoDBiEOG7VTF1M.

    Family and domain databases

    Gene3Di3.30.70.1220. 1 hit.
    InterProiIPR009400. TFIIH_TTDA/Tfb5.
    [Graphical view]
    PfamiPF06331. Tbf5. 1 hit.
    [Graphical view]
    SUPFAMiSSF142897. SSF142897. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0C0X3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLVASKGVLV QCDPSIKALI IQIDSSSSGI ILEELDETHL LIQHDKVNFV   50
    KSELNRLLSK NIYNPFEEE 69
    Length:69
    Mass (Da):7,767
    Last modified:January 10, 2006 - v1
    Checksum:iFB2E15632254DA25
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000111 Genomic DNA. No translation available.
    AACQ01000115 Genomic DNA. No translation available.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000111 Genomic DNA. No translation available.
    AACQ01000115 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali P0C0X3.
    SMRi P0C0X3. Positions 4-65.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAF0007011.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    CGDi CAF0007011. orf19.4439.1.

    Phylogenomic databases

    eggNOGi NOG148452.
    OrthoDBi EOG7VTF1M.

    Family and domain databases

    Gene3Di 3.30.70.1220. 1 hit.
    InterProi IPR009400. TFIIH_TTDA/Tfb5.
    [Graphical view ]
    Pfami PF06331. Tbf5. 1 hit.
    [Graphical view ]
    SUPFAMi SSF142897. SSF142897. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiTFB5_CANAL
    AccessioniPrimary (citable) accession number: P0C0X3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 10, 2006
    Last sequence update: January 10, 2006
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3