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P0C0X3 (TFB5_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase II transcription factor B subunit 5
Alternative name(s):
General transcription and DNA repair factor IIH subunit 5
Short name=TFIIH subunit 5
Gene names
Name:TFB5
ORF Names:CaO19.11919.1, CaO19.4439.1
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length69 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the general transcription and DNA repair factor IIH (TFIIH), which is essential for both basal and activated transcription, as well as for nucleotide excision repair (NER) of DNA. TFB5 is required for stable recruitment of TFIIH to a promoter, but not for stability of TFIIH subunits By similarity.

Subunit structure

Component of the core TFIIH complex By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the TFB5 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6969RNA polymerase II transcription factor B subunit 5
PRO_0000119278

Sequences

Sequence LengthMass (Da)Tools
P0C0X3 [UniParc].

Last modified January 10, 2006. Version 1.
Checksum: FB2E15632254DA25

FASTA697,767
        10         20         30         40         50         60 
MLVASKGVLV QCDPSIKALI IQIDSSSSGI ILEELDETHL LIQHDKVNFV KSELNRLLSK 


NIYNPFEEE 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000111 Genomic DNA. No translation available.
AACQ01000115 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalP0C0X3.
SMRP0C0X3. Positions 4-65.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAF0007011.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

CGDCAF0007011. orf19.4439.1.

Phylogenomic databases

eggNOGNOG148452.
OrthoDBEOG7VTF1M.

Family and domain databases

Gene3D3.30.70.1220. 1 hit.
InterProIPR009400. TFIIH_TTDA/Tfb5.
[Graphical view]
PfamPF06331. Tbf5. 1 hit.
[Graphical view]
SUPFAMSSF142897. SSF142897. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTFB5_CANAL
AccessionPrimary (citable) accession number: P0C0X3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names