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Protein

RNA polymerase II transcription factor B subunit 5

Gene

TFB5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the general transcription and DNA repair factor IIH (TFIIH), which is essential for both basal and activated transcription, as well as for nucleotide excision repair (NER) of DNA. TFB5 is required for stable recruitment of TFIIH to a promoter, but not for stability of TFIIH subunits (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processDNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase II transcription factor B subunit 5
Alternative name(s):
General transcription and DNA repair factor IIH subunit 5
Short name:
TFIIH subunit 5
Gene namesi
Name:TFB5
Ordered Locus Names:CAALFM_C107280CA
ORF Names:CaO19.11919.1, CaO19.4439.1
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 1

Organism-specific databases

CGDiCAL0000181098. orf19.4439.1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001192781 – 69RNA polymerase II transcription factor B subunit 5Add BLAST69

Interactioni

Subunit structurei

Component of the core TFIIH complex.By similarity

Structurei

3D structure databases

ProteinModelPortaliP0C0X3.
SMRiP0C0X3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TFB5 family.Curated

Phylogenomic databases

InParanoidiP0C0X3.
KOiK10845.
OrthoDBiEOG092C5WAI.

Family and domain databases

Gene3Di3.30.70.1220. 1 hit.
InterProiView protein in InterPro
IPR035935. TFB5-like_sf.
IPR009400. TFIIH_TTDA/Tfb5.
PANTHERiPTHR28580. PTHR28580. 1 hit.
PfamiView protein in Pfam
PF06331. Tfb5. 1 hit.
SMARTiView protein in SMART
SM01395. Tbf5. 1 hit.
SUPFAMiSSF142897. SSF142897. 1 hit.

Sequencei

Sequence statusi: Complete.

P0C0X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVASKGVLV QCDPSIKALI IQIDSSSSGI ILEELDETHL LIQHDKVNFV
60
KSELNRLLSK NIYNPFEEE
Length:69
Mass (Da):7,767
Last modified:January 10, 2006 - v1
Checksum:iFB2E15632254DA25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017623 Genomic DNA. Translation: AOW26380.1.
RefSeqiXP_019330670.1. XM_019475125.1.

Genome annotation databases

GeneIDi30515021.
KEGGical:CAALFM_C107280CA.

Similar proteinsi

Entry informationi

Entry nameiTFB5_CANAL
AccessioniPrimary (citable) accession number: P0C0X3
Secondary accession number(s): A0A1D8PE18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 22, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families