Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RNA polymerase II transcription factor B subunit 5

Gene

TFB5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the general transcription and DNA repair factor IIH (TFIIH), which is essential for both basal and activated transcription, as well as for nucleotide excision repair (NER) of DNA. TFB5 is required for stable recruitment of TFIIH to a promoter, but not for stability of TFIIH subunits (By similarity).By similarity

GO - Biological processi

  1. nucleotide-excision repair Source: InterPro
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase II transcription factor B subunit 5
Alternative name(s):
General transcription and DNA repair factor IIH subunit 5
Short name:
TFIIH subunit 5
Gene namesi
Name:TFB5
ORF Names:CaO19.11919.1, CaO19.4439.1
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559 Componenti: Unassembled WGS sequence

Organism-specific databases

CGDiCAF0007011. orf19.4439.1.

Subcellular locationi

  1. Nucleus By similarity

GO - Cellular componenti

  1. core TFIIH complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6969RNA polymerase II transcription factor B subunit 5PRO_0000119278Add
BLAST

Interactioni

Subunit structurei

Component of the core TFIIH complex.By similarity

Protein-protein interaction databases

STRINGi5476.CAF0007011.

Structurei

3D structure databases

ProteinModelPortaliP0C0X3.
SMRiP0C0X3. Positions 4-65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TFB5 family.Curated

Phylogenomic databases

eggNOGiNOG148452.
InParanoidiP0C0X3.
OrthoDBiEOG7VTF1M.

Family and domain databases

Gene3Di3.30.70.1220. 1 hit.
InterProiIPR009400. TFIIH_TTDA/Tfb5.
[Graphical view]
PfamiPF06331. Tbf5. 1 hit.
[Graphical view]
SUPFAMiSSF142897. SSF142897. 1 hit.

Sequencei

Sequence statusi: Complete.

P0C0X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVASKGVLV QCDPSIKALI IQIDSSSSGI ILEELDETHL LIQHDKVNFV
60
KSELNRLLSK NIYNPFEEE
Length:69
Mass (Da):7,767
Last modified:January 10, 2006 - v1
Checksum:iFB2E15632254DA25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000111 Genomic DNA. No translation available.
AACQ01000115 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000111 Genomic DNA. No translation available.
AACQ01000115 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliP0C0X3.
SMRiP0C0X3. Positions 4-65.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5476.CAF0007011.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

CGDiCAF0007011. orf19.4439.1.

Phylogenomic databases

eggNOGiNOG148452.
InParanoidiP0C0X3.
OrthoDBiEOG7VTF1M.

Family and domain databases

Gene3Di3.30.70.1220. 1 hit.
InterProiIPR009400. TFIIH_TTDA/Tfb5.
[Graphical view]
PfamiPF06331. Tbf5. 1 hit.
[Graphical view]
SUPFAMiSSF142897. SSF142897. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiTFB5_CANAL
AccessioniPrimary (citable) accession number: P0C0X3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: January 7, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.