Reviewed,
UniProtKB/Swiss-Prot P0C0W1 (RS22A_YEAST)
Last modified
December 15, 2009.
Version 42.
History...
Clusters with 100%,
90%,
50% identity |
Documents (5) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: 40S ribosomal protein S22-A Alternative name(s): S24 YS22 RP50 YP58 | ||||||||
| Gene names |
| ||||||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 130 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subunit structure | Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.5 |
| Subcellular location | Cytoplasm By similarity. |
| Miscellaneous | Present with 40400 molecules/cell in log phase SD medium. Ref.7 There are 2 genes for S22 in yeast. |
| Sequence similarities | Belongs to the ribosomal protein S8P family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Ribonucleoprotein Ribosomal protein |
| Technical term | 3D-structure Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | translation Ref.4 Inferred by curator. Source: SGD |
| Cellular component | cytosolic small ribosomal subunit Ref.4 Inferred from direct assay. Source: SGD |
| Molecular function | structural constituent of ribosome Ref.4 Inferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed." Leer R.J., van Raamsdonk-Duin M.M.C., Kraakman P., Mager W.H., Planta R.J. Nucleic Acids Res. 13:701-709(1985) [PubMed: 4000930] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes." Purnelle B., Coster F., Goffeau A. Yeast 10:1235-1249(1994) [PubMed: 7754713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [3] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. Karpfinger-Hartl L.EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [4] | "Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast." Otaka E., Higo K., Osawa S. Biochemistry 21:4545-4550(1982) [PubMed: 6814480] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-44. |
| [5] | "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed: 9559554] [Abstract] Cited for: NOMENCLATURE, SUBUNIT. |
| [6] | "The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed: 10601260] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE. |
| [7] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [8] | "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions." Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J. Cell 107:373-386(2001) [PubMed: 11701127] [Abstract] Cited for: 3D-STRUCTURE MODELING OF 4-130, ELECTRON MICROSCOPY. |
| [9] | "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation." Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J. EMBO J. 23:1008-1019(2004) [PubMed: 14976550] [Abstract] Cited for: 3D-STRUCTURE MODELING, ELECTRON MICROSCOPY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| X01962 Genomic DNA. Translation: CAA25998.1. X77688 Genomic DNA. Translation: CAA54770.1. Z49465 Genomic DNA. Translation: CAA89485.1. | |||||||||||||||||||
| PIR | R4BY24. A23082. | ||||||||||||||||||
| RefSeq | NP_012345.1. | ||||||||||||||||||
3D structure databases | |||||||||||||||||||
| |||||||||||||||||||
| SMR | P0C0W1. Positions 4-130. | ||||||||||||||||||
| ModBase | Search... | ||||||||||||||||||
Protein-protein interaction databases | |||||||||||||||||||
| DIP | DIP-5473N. | ||||||||||||||||||
| IntAct | P0C0W1. 49 interactions. | ||||||||||||||||||
| STRING | P0C0W1. | ||||||||||||||||||
Proteomic databases | |||||||||||||||||||
| PeptideAtlas | P0C0W1. | ||||||||||||||||||
| PRIDE | P0C0W1. | ||||||||||||||||||
Genome annotation databases | |||||||||||||||||||
| Ensembl | YJL190C; YJL190C; YJL190C; Saccharomyces cerevisiae. [Genome view] | ||||||||||||||||||
| GeneID | 853249. | ||||||||||||||||||
| KEGG | sce:YJL190C. | ||||||||||||||||||
| NMPDR | fig|4932.3.peg.3309. | ||||||||||||||||||
Organism-specific databases | |||||||||||||||||||
| CYGD | YJL190c. | ||||||||||||||||||
| SGD | S000003726. RPS22A. | ||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||
| HOGENOM | HBG735443. | ||||||||||||||||||
| OMA | IKPRFPV. | ||||||||||||||||||
| OrthoDB | EOG9J12S5. | ||||||||||||||||||
Gene expression databases | |||||||||||||||||||
| ArrayExpress | P0C0W1. | ||||||||||||||||||
| Genevestigator | P0C0W1. | ||||||||||||||||||
Family and domain databases | |||||||||||||||||||
| InterPro | IPR000630. Ribosomal_S8. [Graphical view] | ||||||||||||||||||
| PANTHER | PTHR11758. Ribosomal_S8. 1 hit. | ||||||||||||||||||
| Pfam | PF00410. Ribosomal_S8. 1 hit. [Graphical view] | ||||||||||||||||||
| PROSITE | PS00053. RIBOSOMAL_S8. 1 hit. [Graphical view] | ||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||
Other Resources | |||||||||||||||||||
| NextBio | 973490. | ||||||||||||||||||
Entry information
| Entry name | RS22A_YEAST | ||||||||
| Accession | Primary (citable) accession number: P0C0W1 Secondary accession number(s): P04648 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| Ribosomal proteins Ribosomal proteins families and list of entries |
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome X Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names |

Clusters with


