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Protein

Anti-sigma-B factor antagonist

Gene

rsbV

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma-B factor antagonist
Alternative name(s):
Anti-anti-sigma-B factor
Gene namesi
Name:rsbV
Ordered Locus Names:SE_1670
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000001411 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001941961 – 108Anti-sigma-B factor antagonistAdd BLAST108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei57PhosphoserineBy similarity1

Post-translational modificationi

Phosphorylated by RsbW on a serine residue.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi176280.SE1670.

Structurei

3D structure databases

ProteinModelPortaliP0C0Q8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 108STASPROSITE-ProRule annotationAdd BLAST106

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105WN5. Bacteria.
COG1366. LUCA.
KOiK04749.
OMAiHLLVNME.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0C0Q8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLNIETITH DDFYEVKVGG ELDVYTVPEL EEVLVPMRQE GTHDVHVNLA
60 70 80 90 100
NVSYMDSTGL GLFVGTLKAL NQNDKNLYIL GVSERIGRLF DITGLKDLMH

VNEGTEVE
Length:108
Mass (Da):12,093
Last modified:November 22, 2005 - v1
Checksum:iDE3C2F0EC160D1B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO05269.1.
RefSeqiNP_765225.1. NC_004461.1.
WP_001829952.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO05269; AAO05269; SE_1670.
GeneIDi1057168.
KEGGisep:SE1670.
PATRICi19609204. VBIStaEpi113981_1631.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO05269.1.
RefSeqiNP_765225.1. NC_004461.1.
WP_001829952.1. NC_004461.1.

3D structure databases

ProteinModelPortaliP0C0Q8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176280.SE1670.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO05269; AAO05269; SE_1670.
GeneIDi1057168.
KEGGisep:SE1670.
PATRICi19609204. VBIStaEpi113981_1631.

Phylogenomic databases

eggNOGiENOG4105WN5. Bacteria.
COG1366. LUCA.
KOiK04749.
OMAiHLLVNME.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRSBV_STAES
AccessioniPrimary (citable) accession number: P0C0Q8
Secondary accession number(s): Q8VSV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.